Results 21 to 30 of about 2,401,730 (258)

Gac two-component system in Pseudomonas syringae pv. tabaci is required for virulence but not for hypersensitive reaction [PDF]

, 2008
Pseudomonas syringae pv. tabaci 6605 causes wildfire disease on host tobacco plants. To investigate the regulatory mechanism of the expression of virulence, Gac two-Component system-defective mutants, Delta gacA and Delta gacS, and a double mutant, Delta
Ichinose, Yuki, Marutani, Mizuri, Ogawa, Yujiro, Yoshishige, Inagaki, Toyoda, Kazuhiro, Shiraishi, Tomonori, Taguchi, Fumiko, Hossain, Mijan Md.   +7 more
core   +1 more source

FNR Regulates the Expression of Important Virulence Factors Contributing to the Pathogenicity of Avian Pathogenic Escherichia coli

Frontiers in Cellular and Infection Microbiology, 2017
Avian pathogenic Escherichia coli (APEC) is the etiologic agent of colibacillosis, an important cause of morbidity and mortality in poultry. Though, many virulence factors associated with APEC pathogenicity are known, their regulation remains unclear ...
Nicolle L. Barbieri, Jessica A. Vande Vorde, Alison R. Baker, Fabiana Horn, Ganwu Li, Catherine M. Logue, Lisa K. Nolan, Lisa K. Nolan   +7 more
doaj   +1 more source

TroA of Streptococcus suis is required for manganese acquisition and full virulence [PDF]

, 2011
Streptococcus suis causes infections in pigs and occasionally in humans resulting in 23 manifestations as meningitis, sepsis, arthritis and septic shock. For survival within the 24 host, S. suis requires numerous nutrients including trace metals.
Smith, H.E., Rebel, M.J., Wichers Schreur, P.J., Rebel, J.M.J., van Putten, J.P.M., Jos P. M. van Putten, Johanna M. J. Rebel, Mari A. Smits, Paul J. Wichgers Schreur, Smits, M.A., Hilde E. Smith, Wichgers Schreur, P.J., Putten, J.P.M., van   +12 more
core   +1 more source

Selection of virulence-associated determinants of Streptococcus suis serotype 2 by in vivo complementation [PDF]

, 2001
Within Streptococcus suis serotype 2, pathogenic, weakly pathogenic, and nonpathogenic strains can be found. We introduced a genomic library of a pathogenic strain into a weakly pathogenic strain.
Smith, H.E., Henk J. Wisselink, Wisselink, H.J., Mari A. Smits, Smits, M.A., Hilde E. Smith, Herma Buijs, Norbert Stockhofe-Zurwieden, Buijs, H., Stockhofe Zurwieden, N.   +9 more
core   +1 more source

Optimal Response to Quorum-Sensing Signals Varies in Different Host Environments with Different Pathogen Group Size

mBio, 2020
The persistence of genetic variation in master regulators of gene expression, such as quorum-sensing systems, is hard to explain. Here, we investigated two alternative hypotheses for the prevalence of polymorphic quorum sensing in Gram-positive bacteria,
Liqin Zhou, Leyla Slamti, Didier Lereclus, Ben Raymond   +3 more
doaj   +1 more source

Predicting the virulence of MRSA from its genome sequence [PDF]

, 2014
This work is supported by the EC-FP7 program no. 245500 and the BBSRCMicrobial virulence is a complex and often multifactorial phenotype, intricately linked to a pathogen's evolutionary trajectory.
Josefsson, Elisabet,, Hawkins, E., Josefsson, Elisabet, Holden, M., Yajjala, Vijaya Kumar, Feil, E. J., Read, T. D., Recker, Mario, Rudkin, Justine K., P. D. Fey, Z. Gulay, Kumar Yajjala, Vijaya, Wilson, D., E. J. Feil, Williams, P., T. Widhelm, Sloan, Tim J, Fey, P. D., Gulay, Zeynep, Parfett, S., Gulay, Z., Endres, Jennifer L, M. Recker, Priest, Nicholas K, Hurst, Laurence D, E. Josefsson, Lewis, K., Fey, Paul D, Sloan, Tim J., van den Elsen, J., M. Laabei, Peacock, Sharon J., Priest, Nicholas K., Feil, Edward J., Read, Timothy D., Aldeljawi, Mona, Parfett, Sara, J. K. Rudkin, L. Scowen, Hurst, Laurence D., P. Williams, Widhelm, Todd, S. Parfett, J. L. Endres, N. K. Priest, S. J. Peacock, Massey, R. C., Holden, Matthew, Peacock, Sharon J, J. van den Elsen, Bayles, Kenneth W., M. Holden, Massey, Ruth C., Scowen, L., Feil, Edward J, Rudkin, J. K., Hurst, L. D., E. Hawkins, M. Aldeljawi, Rudkin, Justine K, Read, Timothy D, K. W. Bayles, V. K. Yajjala, Wilson, Daniel, T. J. Sloan, L. D. Hurst, Recker, M., Aldeljawi, M., D. Wilson, Bayles, K. W., Laabei, Maisem, K. Lewis, Bayles, Kenneth W, Scowen, Lucy, Endres, J. L., Laabei, M., Hawkins, Erica, Yajjala, V. K., Williams, Paul, Sloan, T. J., Massey, Ruth C, Lewis, Katie, Endres, Jennifer L., Fey, Paul D., Peacock, S. J., Priest, N. K., van den Elsen, Jean, R. C. Massey, T. D. Read, Widhelm, T.   +89 more
core   +1 more source

The palmitoyl-CoA ligase Fum16 is part of a Fusarium verticillioides fumonisin subcluster involved in self-protection

mBio
Fusarium verticillioides produces the mycotoxin fumonisin B1 (FB1), which disrupts sphingolipid biosynthesis by inhibiting ceramide synthase and affects the health of plants, animals, and humans. The means by which F. verticillioides protects itself from
Fabio Gherlone, Katarina Jojić, Ying Huang, Sandra Hoefgen, Vito Valiante, Slavica Janevska   +5 more
doaj   +1 more source

The genome of a pathogenic rhodococcus : cooptive virulence underpinned by key gene acquisitions [PDF]

, 2010
We report the genome of the facultative intracellular parasite Rhodococcus equi, the only animal pathogen within the biotechnologically important actinobacterial genus Rhodococcus. The 5.0-Mb R.
Parkhill Julian, Cherevach, Inna, Iain Macarthur, Sanders Mandy, Leadon, Desmond, Prescott John F., Navas, Jesús, Michal Letek, González Patricia, Tom C. Freeman, Navas Méndez, Jesús, Valero-Rello, Ana, Ruth Fahey, Leadon Desmond, Bentley, Stephen D., Holdstock Jolyon, Ursula Fogarty, Scortti, Mariela M., Hapeshi, Alexia, José A. Vázquez-Boland, Inna Cherevach, Buckley, Tom, Rodríguez, Héctor M., Rodríguez Héctor, Ocampo Alain, Valero-Rello Ana, Fogarty Ursula, Valero Rello, Ana, Prescott, John F., Quail Michael A., Rodríguez, Héctor, Jolyon Holdstock, Alain Ocampo, Sanders, Mandy, Héctor Rodríguez, Fogarty, Ursula, Vázquez-Boland José A., Ana Valero-Rello, MacArthur Iain, Freeman Tom C., González, Patricia, Ocampo, Alain, Ana Valero-Rello, Fahey Ruth, Desmond Leadon, Cherevach Inna, Blanco, Mónica, Mariela M. Scortti, MacArthur, Iain, Vázquez Boland, José A., Bentley Stephen D., John F Prescott, Wim G. Meijer, Quail, Michael A., John F. Prescott, Stephen D. Bentley, Vázquez-Boland, José A., José A Vázquez-Boland, Holdstock, Jolyon, Stephen D Bentley, Letek Michal, Meijer, Wim G., Blanco Mónica, Meijer Wim G., Mónica Blanco, Ocampo Sosa, Alain Antonio, Tom C Freeman, Julian Parkhill, Jolyon Holdstock, Hapeshi Alexia, Tom Buckley, Wim G Meijer, Mandy Sanders, Michael A. Quail, Letek, Michal, Michael A Quail, Alexia Hapeshi, Scortti Mariela M., Parkhill, Julian, Navas Jesús, Patricia González, Mariela M Scortti, González, Patricia Jiménez, Buckley Tom, Freeman, Tom C., Fahey, Ruth, Jesús Navas   +86 more
core   +1 more source

A Conserved Cysteine Residue in Coxsackievirus B3 Protein 3A with Implication for Elevated Virulence

Viruses, 2022
Enteroviruses (EV) are implicated in an extensive range of clinical manifestations, such as pancreatic failure, cardiovascular disease, hepatitis, and meningoencephalitis.
Martin Voss, Sandra Pinkert, Meike Kespohl, Niclas Gimber, Karin Klingel, Jan Schmoranzer, Michael Laue, Matthias Gaida, Peter-Michael Kloetzel, Antje Beling   +9 more
doaj   +1 more source

Evolution of Salmonella-Host Cell Interactions through a Dynamic Bacterial Genome

Frontiers in Cellular and Infection Microbiology, 2017
Salmonella Typhimurium has a broad arsenal of genes that are tightly regulated and coordinated to facilitate adaptation to the various host environments it colonizes. The genome of Salmonella Typhimurium has undergone multiple gene acquisition events and
Bushra Ilyas, Bushra Ilyas, Caressa N. Tsai, Caressa N. Tsai, Brian K. Coombes   +4 more
doaj   +1 more source