Results 31 to 40 of about 421,443 (284)

2020 Taiwan consensus statement on the management of hepatitis C: Part (II) special populationsRecommendationsRecommendationsRecommendationsRecommendationsRecommendationsRecommendationsRecommendationsRecommendationsRecommendationsRecommendationsRecommendationsRecommendationsRecommendationsRecommendations

Journal of the Formosan Medical Association, 2020
Hepatitis C virus (HCV) infection is a silent killer that leads to rapid progression of liver cirrhosis and hepatocellular carcinoma (HCC). High prevalence of HCV infection has been reported in Taiwan, especially in high-risk populations including people
Ming-Lung Yu, Pei-Jer Chen, Chia-Yen Dai, Tsung-Hui Hu, Chung-Feng Huang, Yi-Hsiang Huang, Chao-Hung Hung, Chun-Yen Lin, Chen-Hua Liu, Chun-Jen Liu, Cheng-Yuan Peng, Han-Chieh Lin, Jia-Horng Kao, Wan-Long Chuang   +13 more
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Substitution at rt269 in Hepatitis B Virus Polymerase Is a Compensatory Mutation Associated with Multi-Drug Resistance. [PDF]

PLoS ONE, 2015
The emergence of compensatory mutations in the polymerase gene of drug resistant hepatitis B virus (HBV) is associated with treatment failure. We previously identified a multi-drug resistant HBV mutant, which displayed resistance towards lamivudine (LMV),
Sung Hyun Ahn, Doo Hyun Kim, Ah Ram Lee, Beom Kyung Kim, Yong Kwang Park, Eun-Sook Park, Sang Hoon Ahn, Gu-Choul Shin, Soree Park, Hong Seok Kang, Jin-Kyu Rhee, Sung-Il Yang, Youhoon Chong, Kyun-Hwan Kim   +13 more
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Evaluation of Non-HIV-Related, Drug-Sensitive Cluster Outbreaks of Tuberculosis with PCR-based DNA Fingerprinting

Canadian Respiratory Journal, 1996
OBJECTIVES: To characterize two cluster outbreaks of tuberculosis by DNA fingerprinting and to evaluate the possibility of their association with human immunodeficiency virus (HIV) infection and multiple drug-resistant Mycobacterium tuberculosis.
JM FitzGerald, WA Black, D Kunimoto
doaj   +1 more source

Protease mediated maturation of HIV: Inhibitors of protease and the maturation process [PDF]

, 2012
Protease-mediated maturation of HIV-1 virus particles is essential for virus infectivity. Maturation occurs concomitant with immature virus particle release and is mediated by the viral protease (PR), which sequentially cleaves the Gag and Gag-Pol ...
Catherine S. Adamson, Adamson, Catherine S   +1 more
core   +1 more source

Efficacy of glecaprevir and pibrentasvir treatment for genotype 1b hepatitis C virus drug resistance-associated variants in humanized mice

Journal of General Virology, 2019
Combination therapy with glecaprevir (GLE) and pibrentasvir (PIB) has high efficacy for pan-genotypic hepatitis C virus (HCV)-infected patients. However, the efficacy for patients who acquired potent NS5A inhibitor resistance-associated variants (RAVs) as a result of failure to respond to previous direct-acting antiviral (DAA) therapies is unclear.
Mitsutaka Osawa, Takuro Uchida, Michio Imamura, Yuji Teraoka, Hatsue Fujino, Takashi Nakahara, Atsushi Ono, Eisuke Murakami, Tomokazu Kawaoka, Daiki Miki, Masataka Tsuge, Akira Hiramatsu, Hiromi Abe-Chayama, C. Nelson Hayes, Grace Naswa Makokha, Hiroshi Aikata, Yuji Ishida, Chise Tateno, Yohei Miyayama, Makoto Hijikata, Kazuaki Chayama   +20 more
openaire   +2 more sources

Identification of Plant Peptides as Novel Inhibitors of Orthohepevirus A (HEV) Capsid Protein by Virtual Screening

Molecules, 2023
Hepatitis E virus (HEV) is the notable causative agent of acute and chronic hepatic, renal, pancreatic, neurological, and hematopoietic blood cell infections with high risk in immunocompromised patients. Hepatic failure is mostly documented among adults,
Ghulam Mustafa, Hafiza Salaha Mahrosh, Syed Awais Attique, Rawaba Arif, Mohammad Abul Farah, Khalid Mashay Al-Anazi, Sajad Ali   +6 more
doaj   +1 more source

Hepatitis C virus infection epidemiology among people who inject drugs in Europe: a systematic review of data for scaling up treatment and prevention. [PDF]

, 2014
BACKGROUND: People who inject drugs (PWID) are a key population affected by hepatitis C virus (HCV). Treatment options are improving and may enhance prevention; however access for PWID may be poor.
Mcdonald, B, Hope, V, Basso, M, Eramova, I, Abel-Ollo, Katri, Sperle, Ida, Michot, I, Sperle, Ide, Hatzakis Angelos, Van Houdt, Sabine, Ferri, Marica, Griffiths, Paul, Lazarus Jeffrey V., Vickerman Peter, Částková, Jitka, Rosińska, Magdalena, Tarjan, A, Maria Prins, Aleixandre, Noelia Llorens, Vivian D. Hope (605401), Klavs, I, Fouchard, Jan, Brummer-Korvenkontio, Henrikki, Grady, Bart, Matheï, Catharina, Brummer-Korvenkontio, H, Berglund, T, Kantzanou Maria, Ncube, F, Lopes, Sofia, Eramova, Irina, Struzik, M, Catharina Matheï (605402), Kostrikis, L, Abagiu, Adrian Octavian, Vickerman, P, Fouchard, J, Goldberg, David, Jauffret-Roustide, Marie, Rehak, V, Fotsiou, Nasia, Mravcik, V, Caplinskiene, Irma, Folch, Cinta, Fotiou, A, Melillo, Jackie, Kustec, T, Hobstová, Jiřina, Lazarus, JV, Lazarus, Jeffrey V., Bravo, Maria Jose, Tarján, Anna, Mathei, C, Brisacier, A-C, Prins, Maria, Demanuele, Carlo Olivari, Isabelle Giraudon, EK, Wiessing, Lucas, Fotiou, Anastasios, Martins, Helena Cortes, Nechanska, B, Hope, Vivian D., Hobstova, J, Marica Ferri (605396), Grady, B, Wiessing, L, Bollaerts, Kaat, Giraudon, Isabelle, Rosinska, M, Fotsiou, N, Bogdanova, V, Struzik, Marta, Hutchinson, Sharon, Cullen, Katelyn J., Wiessing Lucas, Ruta, S, Kustec, Tanja, Catharina Matheï, Vilar, G, Hutchinson, S, Bogdanova, Violeta, Croes, Esther, Op De Coul, Eline, Ida Sperle (605399), Origer, A, Michot, Isabelle, Klavs, Irena, Palladino, C, Angelos Hatzakis (146074), Hatzakis, Angelos, Peter Vickerman, Nesheva, E, Katelyn J Cullen, Lazarus, Jeffrey V, Camilleri, M, Tallo, Tatjana, Brisacier, Anne Claire, Hope Vivian D., Martins, HC, Bollaerts, K, Hope, Vivian D, Goldberg, D, Cullen, KJ, Prins, M, Maria Prins (339491), Gómez, Rosario Sendino, Platt, Lucy, Kantzanou, Maria, EMCDDA DRID group, Hotho, Daphne, Van Houdt, S, Martins, M, Cullen, Katelyn J, Low, Andrea, Thornton, Lelia, Hutchinson, Sharon; id_orcid, Prins Maria, Palladino, Claudia, Tefanova, Valentina, Resende, Maria Emília, Resende, E, Marica Ferri, Kalamara, Eleni, Galvin, B, Karnite, A, Gomez, RS, Zimmermann, R, Ferri, M, Strandberg, J, Bart Grady (605397), Tallo, T, Busch, M, Folch, C, Gazdag, Gábor, Strandberg, Joakim, Jeffrey V Lazarus, Maria Kantzanou (605398), Jeffrey V. Lazarus (250583), Grady Bart, Abel-Ollo, K, Mcdonald, Bethan, Nechanská, Blanka, Lopes, S, Castkova, J, Maria Kantzanou, Ferri Marica, Kopilovic, B, Ruta, Simona, Vivian D. Hope, Gazdag, G, Duran, Domingos, Galvin, Brian, Groshkova, Teodora, Arama, V, Caplinskiene, I, Jeffrey V. Lazarus, Ida Sperle, Kantzanou, M, Croes, E, Garavan, C, Busch, Martin, Cruciani, Mario, Berglund, Torsten, Origer, Alain, Vilar, Graça, Melillo, J, Kopilovic, Boris, Řehák, Vratislav, Hope, VD, Cullen Katelyn J., Low, A, Matheï Catharina, Martins, Mário, Vicente, J, Angelos Hatzakis, Sperle, I, Nesheva, Elmira, Mravčík, Viktor, Platt, L, Demanuele, CO, Ncube, Fortune, Cruciani, M, Zimmermann, Ruth, Tefanova, V, Lucas Wiessing (483360), Lucas Wiessing, Thornton, L, Aleixandre, NL, Groshkova, T, Arama, Victoria, Bravo, MJ, Katelyn J. Cullen (605400), Jauffret-Roustide, M, Abagiu, AO, Sperle Ida, Op de Coul, E, Vivian D Hope, Duran, D, Kostrikis, Leontios, Karnite, Anda, Hotho, D, Yury E. Khudyakov, Bart Grady, Vickerman, Peter, BASSO, MONICA, Griffiths, P, Vicente, Julian, Peter Vickerman (210007), Katelyn J. Cullen, Hatzakis, A, Camilleri, Moses   +210 more
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An Ensemble Matrix Completion Model for Predicting Potential Drugs Against SARS-CoV-2

Frontiers in Microbiology, 2021
Because of the catastrophic outbreak of global coronavirus disease 2019 (COVID-19) and its strong infectivity and possible persistence, computational repurposing of existing approved drugs will be a promising strategy that facilitates rapid clinical ...
Wen Li, Shulin Wang, Junlin Xu
doaj   +1 more source

Molecular monitoring of HIV-1 drug resistance in Ifakara HIV-1 Cohort, Tanzania [PDF]

, 2013
HIV-1 resistance is one of the problems affecting success of antiretroviral therapy programmes worldwide. Many studies on efficacy of ART programmes, specifically on drug resistance, have been conducted in developed countries but not in developing ...
Masimba, Pax Jessey
core   +1 more source

Cryotomography of budding influenza a virus reveals filaments with diverse morphologies that mostly do not bear a genome at their distal end [PDF]

, 2013
Influenza viruses exhibit striking variations in particle morphology between strains. Clinical isolates of influenza A virus have been shown to produce long filamentous particles while laboratory-adapted strains are predominantly spherical.
Swetha Vijayakrishnan, Vijayakrishnan Swetha, Jackson David, Worawit Suphamungmee, David Bhella, Loney Colin, Bhella, D., Swetha Vijayakrishnan (418947), Colin Loney (418948), David Jackson (84936), Frazer J. Rixon (129686), Colin Loney, Suphamungmee Worawit, Rixon, F.J., Jackson, David, Worawit Suphamungmee (418949), Rixon Frazer J., Vijayakrishnan, Swetha, Rixon, Frazer J., Loney, Colin, Bhella David, David Jackson, Loney, C., Suphamungmee, W., Jackson, D., Bhella, David, Vijayakrishnan, S., David Bhella (129684), Suphamungmee, Worawit, Frazer J Rixon   +29 more
core   +1 more source