Results 41 to 50 of about 421,443 (284)

Exploring associations between perceived HCV status and injecting risk behaviors among recent initiates to injecting drug use in Glasgow

, 2008
The aim of this study was to explore the influence of testing for hepatitis C virus (HCV) and perceived HCV status on injecting risk behavior. A cross-sectional, community-wide survey was undertaken at multiple sites throughout Greater Glasgow during ...
Hutchinson, S.J.; id_orcid, Palmateer, N., Wadd, S., Taylor, Avril, Palmateer, Norah, Wadd, Sarah, Goldberg, David, Palmateer, Norah; id_orcid, Anderson, N., Goldberg, D.J., Hutchinson, Sharon, Anderson, Niall, Hutchinson, S.J., Taylor, A.   +13 more
core   +1 more source

Drug-induced Hypersensitivity Syndrome Associated with a Marked Increase in Anti-paramyxovirus Antibody Titers in a Scleroderma Patient

Allergology International, 2007
Background: Drug-induced hypersensitivity syndrome (DIHS) is characterized by a severe multiorgan hypersensitivity reaction that usually appears after prolonged exposure to certain drugs and may be related to reactivation of herpes viruses.
Taio Naniwa, Shinji Maeda, Hiroo Sawada, Yuko Watanabe, Tomoyo Osawa, Yoshihito Hayami, Shogo Banno, Akimichi Morita, Ryuzo Ueda   +8 more
doaj   +1 more source

The Role of Hematopoietic Cell Transplantation in Ataxia‐Telangiectasia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Ataxia‐telangiectasia (A‐T) is a DNA repair disorder characterized by neurodegeneration, immunodeficiency, and cancer predisposition. Hematopoietic cell transplantation (HCT) is an established therapy in related disorders such as Fanconi anemia (FA) and Nijmegen breakage syndrome (NBS), but its role in A‐T is unclear.
Laila Alkhouli, Seth Rotz, Masatoshi Takagi, Richa Sharma   +3 more
wiley   +1 more source

The processes of reform in Victoria’s alcohol and other drug sector, 2011-2014 [PDF]

, 2014
This paper explores issues and concerns related to the 2014 alcohol and other drug sector recommissioning process in Victoria. Overview In mid-2014, the Victorian Alcohol and Drug Association approached the Drug Policy Modelling Program, at the ...
Drug Policy Modelling Program
core  

Harm reduction among injecting drug users - evidence of effectiveness

, 2010
This chapter synthesises and evaluates the available direct evidence relating to the impact of needle and syringe programmes (NSPs), opioid substitution treatment (OST), drug consumption rooms (DCRs), and peer naloxone distribution (PND) on HIV/hepatitis
Rhodes, T., Kerr, Thomas, Palmateer, N., Goldberg, David J., Hedrich, Dagmar, Palmateer, Norah, Fry, Craig L, Goldberg, David, Palmateer, Norah; id_orcid, Rhodes, Tim, Goldberg, D.J., Stöver, H., Hickman, Matthew, Hutchinson, Sharon, Hall, Wayne, Hickman, M., Brentari, C., Kimber, J., Kimber, Jo, Fischer, Benedikt, Hutchinson, S.J., Stevens, Alex, Dubois-Arber, Françoise, Hutchinson, Sharon J.; id_orcid   +23 more
core   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Hepatitis C virus infection among non-IDU HIV-infected and uninfected men who have sex with men.

Mediterranean Journal of Hematology and Infectious Diseases, 2011
In the Mediterranean countries, hepatitis C virus infection affect nearly 45% of HIV-1 infected individuals, consistently to the high proportion of patients with a history of intravenous drug use and exposed to the two viruses by parenteral route.
Massimo Giuliani, Lorenzo Nosotti, Alessandra Latini, Concetta Mirisola, Fulvia Pimpinelli, Sabrina Volpi, Fabrizio Ensoli, Gianpaolo Impara, Guido Palamara   +8 more
doaj   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Reduced susceptibility of human immunodeficiency virus type 1 (HIV-1) from patients with primary HIV infection to nonnucleoside reverse transcriptase inhibitors is associated with variation at novel amino acid sites [PDF]

, 2000
Recently, significant numbers of individuals with primary human immunodeficiency virus (HN) infection have been found to harbor viral strains with reduced susceptibility to antiretroviral drugs.
Jeannette M. Whitcomb, Susan J. Little, Philip H. Keiser, Hellmann, N S, Connick, E, D'Aquila, R T, Elizabeth Connick, Douglas D. Richman, Christos J. Petropoulos, Richard T. D'Aquila, Whitcomb, J M, Joseph K. Wong, Keiser, P H, Brown, A J, Wong, J K, Richman, D D, Heather M. Precious, Eric S. Daar, Huang, W, Wei Huang, Precious, H M, Nicholas S. Hellmann, Marlynne Quigg, Quigg, M, Daar, E S, Little, S J, Andrew J. Leigh Brown, Petropoulos, C J   +27 more
core   +1 more source

Antiviral Effects of Hydroxychloroquine and Type I Interferon on In Vitro Fatal Feline Coronavirus Infection

Viruses, 2020
Feline infectious peritonitis (FIP) is a viral disease with a high morbidity and mortality by the FIP virus (FIPV, virulent feline coronavirus). Several antiviral drugs for FIP have been identified, but many of these are expensive and not available in ...
Tomomi Takano, Kumi Satoh, Tomoyoshi Doki, Taishi Tanabe, Tsutomu Hohdatsu   +4 more
doaj   +1 more source