Results 1 to 10 of about 253,283 (242)

Virus-host interactions predictor (VHIP): Machine learning approach to resolve microbial virus-host interaction networks. [PDF]

open access: yesPLoS Comput Biol, 2023
Viruses of microbes are ubiquitous biological entities that reprogram their hosts’ metabolisms during infection in order to produce viral progeny, impacting the ecology and evolution of microbiomes with broad implications for human and environmental health.
Bastien GE   +5 more
europepmc   +3 more sources

Virus-host interaction networks as new antiviral drug targets for IAV and SARS-CoV-2 [PDF]

open access: yesEmerging Microbes and Infections, 2022
Currently, SARS-CoV-2, especially the Omicron strain, is ravaging the world and even co-infecting human beings with IAV, which is a serious threat to human public health. As of yet, no specific antiviral drug has been discovered for SARS-CoV-2.
Na Chen   +4 more
doaj   +2 more sources

Emerging translation strategies during virus-host interaction. [PDF]

open access: yesWiley Interdiscip Rev RNA, 2021
AbstractTranslation control is crucial during virus–host interaction. On one hand, viruses completely rely on the protein synthesis machinery of host cells to propagate and have evolved various mechanisms to redirect the host's ribosomes toward their viral mRNAs.
Hoang HD, Neault S, Pelin A, Alain T.
europepmc   +4 more sources

Bioinformatics approaches for unveiling virus-host interactions

open access: yesComputational and Structural Biotechnology Journal, 2023
The coronavirus disease-2019 (COVID-19) pandemic has elucidated major limitations in the capacity of medical and research institutions to appropriately manage emerging infectious diseases.
Hitoshi Iuchi   +8 more
doaj   +3 more sources

Viruses.STRING: A Virus-Host Protein-Protein Interaction Database [PDF]

open access: yesViruses, 2018
As viruses continue to pose risks to global health, having a better understanding of virus–host protein–protein interactions aids in the development of treatments and vaccines.
Helen Victoria Cook   +4 more
doaj   +6 more sources

Virus–Host Cell Interactions [PDF]

open access: yesCells, 2022
As obligate intracellular parasites, viruses are intimately interconnected with their host cells [...]
Thomas Hoenen, Allison Groseth
openaire   +3 more sources

Role of Lipid Transfer Proteins (LTPs) in the Viral Life Cycle

open access: yesFrontiers in Microbiology, 2021
Viruses are obligate parasites that depend on the host cell machinery for their replication and dissemination. Cellular lipids play a central role in multiple stages of the viral life cycle such as entry, replication, morphogenesis, and egress.
Kiran Avula   +6 more
doaj   +1 more source

HIV-1 Natural Antisense Transcription and Its Role in Viral Persistence

open access: yesViruses, 2021
Natural antisense transcripts (NATs) represent a class of RNA molecules that are transcribed from the opposite strand of a protein-coding gene, and that have the ability to regulate the expression of their cognate protein-coding gene via multiple ...
Rui Li   +3 more
doaj   +1 more source

High throughput screening of novel AAV capsids identifies variants for transduction of adult NSCs within the subventricular zone

open access: yesMolecular Therapy: Methods & Clinical Development, 2021
The adult mammalian brain entails a reservoir of neural stem cells (NSCs) generating glial cells and neurons. However, NSCs become increasingly quiescent with age, which hampers their regenerative capacity. New means are therefore required to genetically
Lukas P.M. Kremer   +12 more
doaj   +1 more source

Genotype and phenotype of COVID-19: Their roles in pathogenesis

open access: yesJournal of Microbiology, Immunology and Infection, 2021
COVID-19 is a novel coronavirus with an outbreak of unusual viral pneumonia in Wuhan, China, and then pandemic. Based on its phylogenetic relationships and genomic structures the COVID-19 belongs to genera Betacoronavirus.
Leila Mousavizadeh, Sorayya Ghasemi
doaj   +1 more source

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