Results 21 to 30 of about 253,283 (242)
Cellular Lipids—Hijacked Victims of Viruses
Over the millions of years-long co-evolution with their hosts, viruses have evolved plenty of mechanisms through which they are able to escape cellular anti-viral defenses and utilize cellular pathways and organelles for replication and production of ...
Bozena Omasta, Jana Tomaskova
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Roles of lncRNAs in influenza virus infection
Recent studies have identified host long noncoding RNAs (lncRNAs) as key regulators of host-virus interactions during viral infection. The influenza A virus (IAV) remains a serious threat to public health and economic stability.
Jing Wang, Shan Cen
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Viruses display remarkable specificity in both the host species and the cell types that they infect. Understanding this specificity reveals insight into the basic host components that are required for the viral life cycle and host restriction factors that limit the virus.
openaire +1 more source
Virogenomics: the virus–host interaction revisited
Genomics tools allow us to assess gene expression 'genome wide' providing an unprecedented view on the host-side of the virus-host interaction. The success of the application of these tools crucially depends on our ability to reduce the total information load while increasing the information density of the data collected.
Andeweg, Arno +2 more
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AAV vector-mediated in vivo reprogramming into pluripotency
In vivo reprogramming of somatic cells is hampered by the need for vectors to express the OKSM factors in selected organs. Here the authors report new AAV-based vectors capable of in vivo reprogramming at low doses.
Elena Senís +12 more
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MotivationBeside socio-economic issues, coronavirus pandemic COVID-19, the infectious disease caused by the newly discovered coronavirus SARS-CoV-2, has caused a deep impact in the scientific community, that has considerably increased its effort to ...
Mercè Llabrés, Gabriel Valiente
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Comprehensive host-pathogen protein-protein interaction network analysis
Background Infectious diseases are a cruel assassin with millions of victims around the world each year. Understanding infectious mechanism of viruses is indispensable for their inhibition.
Babak Khorsand +2 more
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Macrophage Polarization in Virus-Host Interactions [PDF]
Macrophage involvement in viral infections and antiviral states is common. However, this involvement has not been well-studied in the paradigm of macrophage polarization, which typically has been categorized by the dichotomy of classical (M1) and alternative (M2) statuses.
Sang, Yongming +2 more
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Mycophenolic acid (MPA) is an effective antiviral drug in plants, and its action in modulating the activity of KATP channels is already known in animals.
Andrea Luvisi +2 more
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Plus-stranded RNA viruses recruit cellular vesicles and co-opt cellular proteins involved in cellular metabolism and lipid biosynthesis to build viral replicase complexes (VRCs) within the large viral replication compartments. We use tombusviruses (TBSV),
Peter D. Nagy
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