Results 31 to 40 of about 253,283 (242)
Scientific Reports, 2022 Although many studies have observed genome-wide host transposon expression alteration during viral infection, the mechanisms of induction and the impact on the host remain unclear. Utilizing recently published influenza A virus (IAV) time series data and
Steven S. Shen +3 more
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Paradoxical Interplay of Viral and Cellular Functions
Viruses, 2011 Some cellular editing functions can restrict the replication of some viruses but contribute to completion of the life cycle of others. A recent study has identified an isoform of the adenosine deaminase acting on RNA type 1 (ADAR 1) as required for ...
Esteban Domingo
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Functional Landscape of African Swine Fever Virus–Host and Virus–Virus Protein Interactions
Viruses, 2023 Viral replication fully relies on the host cell machinery, and physical interactions between viral and host proteins mediate key steps of the viral life cycle.
Katarzyna Magdalena Dolata +3 more
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mSystems, 2021 Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a positive-strand RNA virus. The viral genome is capped at the 5′ end, followed by an untranslated region (UTR). There is a poly(A) tail at the 3′ end, preceded by a UTR.
Rohit Verma +5 more
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Sensing the danger in mosquito spit
The EMBO JournalFactors contained within mosquito saliva enhance transmission of mosquito-borne viruses to the mammalian host. In this issue, Wang et al (2024) identify AaNRP as a crucial pro-viral factor in Aedes aegypti mosquito saliva that promotes recruitment of ...
Yonca Keskek Turk +2 more
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Host restriction factors in retroviral infection: promises in virus-host interaction
Retrovirology, 2012 Retroviruses have an intricate life cycle. There is much to be learned from studying retrovirus-host interactions. Among retroviruses, the primate lentiviruses have one of the more complex genome structures with three categories of viral genes ...
Zheng Yong-Hui +2 more
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Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
FEBS Letters, EarlyView.This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
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Recognition of human oncogenic viruses by host pattern recognition receptors
Frontiers in Immunology, 2014 Human oncogenic viruses include Epstein-Barr virus (EBV), hepatitis B virus (HBV), hepatitis C virus (HCV), human papilloma virus (HPV), human T-cell lymphotropic virus (HTLV-1), Kaposi’s associated sarcoma virus (KSHV), and Merkel cell polyomavirus ...
Nelson C Di Paolo
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Early Virus–Host Cell Interactions
Journal of Molecular Biology, 2018 International ...
openaire +4 more sources
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source