Results 71 to 80 of about 187,700 (310)
RNA Phage VLP-Based Vaccine Platforms
Virus-like particles from a variety of RNA bacteriophages have turned out to be useful platforms for delivery of vaccine antigens in a highly immunogenic format.
David S. Peabody +3 more
doaj +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
White spot syndrome virus envelope protein VP28 is involved in the systemic infection of shrimp [PDF]
White spot syndrome virus (WSSV) is a large DNA virus infecting shrimp and other crustaceans. The virus particles contain at least five major virion proteins, of which three (VP26, VP24, and VP15) are present in the rod-shaped nucleocapsid and two (VP28 ...
van Hulten, Mariëlle C W +8 more
core +1 more source
Particle-like topologies in light [PDF]
Three-dimensional (3D) topological states resemble truly localised, particle-like objects in physical space. Among the richest such structures are 3D skyrmions and hopfions that realise integer topological numbers in their configuration via homotopic ...
Ramon Droop (10290716) +7 more
core +1 more source
Background Marburg virus (MARV) causes severe haemorrhagic fever in humans and nonhuman primates and has a high mortality rate. However, effective drugs or licensed vaccines are not currently available to control the outbreak and spread of this disease ...
Weiwei Gai +16 more
doaj +1 more source
Virus-like particles as vaccine adjuvants
Virus-like particles (VLPs) consist of one or more viral coat proteins that assemble into particles. They can be taken up by antigen presenting cells (APC), peptides derived from them are presented on MHC class I molecules at the cell surface, and thereby prime a CD8+ T cell response, either against the particle-forming protein itself (such as ...
openaire +3 more sources
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Virus-Like Particles Assembled Using Respiratory Syncytial Virus Matrix Protein Elicit Protective Immunity in Mice [PDF]
Su-Hwa Lee,1,* Ki-Back Chu,2,* Min-Ju Kim,3 Fu-Shi Quan1,2 1Department of Medical Zoology, School of Medicine, Kyung Hee University, Seoul, Republic of Korea; 2Medical Research Center for Bioreaction to Reactive Oxygen Species and Biomedical ...
Chu KB, Quan FS, Lee SH, Kim MJ
core
Towards an improved platform for dengue and Zika virus virus-like particle production [PDF]
FAME analysis Using GC-QTOF with HP-88 (100m) column for the manuscript entitled Towards an improved platform for dengue and Zika virus virus-like particle productionTHIS DATASET IS ARCHIVED AT DANS/EASY, BUT NOT ACCESSIBLE HERE.
Panya, A (via Mendeley Data)
core +1 more source
Marburg virus (MARV) was the first filovirus to be identified following an outbreak of viral hemorrhagic fever disease in Marburg, Germany in 1967. Due to several factors inherent to filoviruses, they are considered a potential bioweapon that could be ...
John M. Dye +8 more
doaj +1 more source

