Results 61 to 70 of about 6,680,139 (200)

Comparative Molecular Biology Approaches for the Production of Poliovirus Virus-Like Particles Using Pichia pastoris

mSphere, 2020
For enteroviruses such as poliovirus (PV), empty capsids, which are antigenically indistinguishable from mature virions, are produced naturally during viral infection.
Lee Sherry, Keith Grehan, Joseph S. Snowden, Michael L. Knight, Oluwapelumi O. Adeyemi, David J. Rowlands, Nicola J. Stonehouse   +6 more
doaj   +1 more source

Cellular phosphoinositides and the maturation of bluetongue virus, a non-enveloped capsid virus. [PDF]

, 2013
BACKGROUND: Bluetongue virus (BTV), a member of Orbivirus genus in the Reoviridae family is a double capsid virus enclosing a genome of 10 double-stranded RNA segments. A non-structural protein of BTV, NS3, which is associated with cellular membranes and
Roy, Polly, Bishnupriya Bhattacharya, Bhattacharya, Bishnupriya, Polly Roy   +3 more
core   +1 more source

High-speed imaging of ESCRT recruitment and dynamics during HIV virus like particle budding.

PLoS ONE, 2020
Endosomal sorting complexes required for transport proteins (ESCRT) catalyze the fission of cellular membranes during budding of membrane away from the cytosol.
Shilpa Gupta, Josh Bromley, Saveez Saffarian   +2 more
doaj   +1 more source

Identification and characterization of a novel non-structural protein of bluetongue virus [PDF]

, 2011
Bluetongue virus (BTV) is the causative agent of a major disease of livestock (bluetongue). For over two decades, it has been widely accepted that the 10 segments of the dsRNA genome of BTV encode for 7 structural and 3 non-structural proteins.
Rixon, F., Palmarini, M., Ratinier Maxime, Ratinier, Maxime, Golder, Matthew, Nunes, S.F., Alessia Armezzani, Sandro Filipe Nunes, Kathryn Allan, Allan Kathryn, Allan, K., Rixon, Frazer, Golder, M., Allan, Kathryn, Nunes Sandro Filipe, Frazer Rixon, Bayoumy, Amr, Shaw, A., Matthew Golder, Franzoni, G., Caporale Marco, Giulia Franzoni, Golder Matthew, Nunes, Sandro Filipe, Bayoumy Amr, Shaw, Andrew, Amr Bayoumy, Palmarini Massimo, Armezzani, A., Shaw Andrew, Palmarini, Massimo, Ratinier, M., Armezzani, Alessia, Franzoni Giulia, Franzoni, Giulia, Maxime Ratinier, Andrew Shaw, Rixon Frazer, Marco Caporale, Massimo Palmarini, Armezzani Alessia, Bayoumy, A., Caporale, Marco, Caporale, M.   +43 more
core   +1 more source

Immunogenicity assessment for vidutolimod: a risk-driven approach for a simplified 1-tiered, singlicate anti-drug antibody testing strategy

Frontiers in Immunology
The bioanalytical strategy for a therapeutic should be driven by the overall immunogenicity risk of the molecule. Vidutolimod, a virus-like particle therapeutic, is being developed with a unique mechanism of action that requires the generation of a ...
Jenny L. Valentine, Stacey Shank, Lisette M. Fred Lucena, Zhiqiang Wang, Colleen McLaughlin Stern, Byung Chul Kim, Kun Lu, Saileta Prabhu, Michael A. Partridge   +8 more
doaj   +1 more source

Role of lipids on entry and exit of bluetongue virus, a complex non-enveloped virus. [PDF]

, 2010
Non-enveloped viruses such as members of Picornaviridae and Reoviridae are assembled in the cytoplasm and are generally released by cell lysis. However, recent evidence suggests that some non-enveloped viruses exit from infected cells without lysis ...
Roy, Polly, Bishnupriya Bhattacharya, Bhattacharya, Bishnupriya, Polly Roy, Bhattacharya, Roy   +5 more
core   +1 more source

Monoclonal antibodies against Hepatitis C genotype 3a virus like particle inhibit virus entry in cell culture system.

PLoS ONE, 2013
The envelope protein (E1-E2) of Hepatitis C virus (HCV) is a major component of the viral structure. The glycosylated envelope protein is considered to be important for initiation of infection by binding to cellular receptor(s) and also known as one of ...
Soma Das, Rohini K Shetty, Anuj Kumar, Radhika Nagamangalam Shridharan, Ranjitha Tatineni, Giriprakash Chi, Anirban Mukherjee, Saumitra Das, Shaila Melkote Subbarao, Anjali Anoop Karande   +9 more
doaj   +1 more source

Defective interfering particles of parainfluenza virus subtype 5 and interferon induction [PDF]

, 2015
The innate immune response is the first line of defence against virus infection. Cells contain a diverse array of pathogen recognition receptors (PRRs) that are able to recognise multiple pathogen associated molecular patterns (PAMPS) that present ...
Short, John A. L.
core   +2 more sources

Immunogenicity of Virus Like Particle Forming Baculoviral DNA Vaccine against Pandemic Influenza H1N1.

PLoS ONE, 2016
An outbreak of influenza H1N1 in 2009, representing the first influenza pandemic of the 21st century, was transmitted to over a million individuals and claimed 18,449 lives.
Yong-Dae Gwon, Sehyun Kim, Yeondong Cho, Yoonki Heo, Hansam Cho, Kihoon Park, Hee-Jung Lee, Jiwon Choi, Haryoung Poo, Young Bong Kim   +9 more
doaj   +1 more source

Tomato spotted wilt virus glycoproteins induce the formation of endoplasmic reticulum- and Golgi-derived pleomorphic membrane structures in plant cells [PDF]

, 2008
Tomato spotted wilt virus (TSWV) particles are spherical and enveloped, an uncommon feature among plant infecting viruses. Previous studies have shown that virus particle formation involves the enwrapment of ribonucleoproteins with viral glycoprotein ...
Kormelink, R.J.M., Foresti, O., Denecke, J., Wellink, J., Goldbach, R.W., Ribeiro, D.M.O.G.   +5 more
core   +1 more source