Results 61 to 70 of about 231,821 (301)

Recombinant Virus-like Particles of Human Parvovirus B19 with the Internal Location of VP1 Unique Region Produced by Hansenula polymorpha

Viruses, 2022
Human parvovirus B19 (HPV B19) is pathogenic to human, which can cause fifth disease, transient aplastic crisis, arthritis, myocarditis, autoimmune disorders, hydrops fetalis, and so on.
Shuai Shao, Qingqing Wang, Yuqin Jin, Xuefeng Zhang, Zhaoming Liu, Shi Chen, Hailan Wu, Sensen Yang, Fang Tang, Jiguo Su, Yu Liang, Jing Zhang, Qiming Li   +12 more
doaj   +1 more source

Mechanical tuning of virus-like particles

Journal of Colloid and Interface Science, 2023
Journal of Colloid and Interface Science ...
Radiom, Milad, Keys, Tim, Turgay, Yagmur, Ali, Ahmed, Preet, Swapan, Chesnov, Serge, Lutz-Bueno, Viviane, Slack, Emma, Mezzenga, Raffaele   +8 more
openaire   +3 more sources

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

High-speed imaging of ESCRT recruitment and dynamics during HIV virus like particle budding.

PLoS ONE, 2020
Endosomal sorting complexes required for transport proteins (ESCRT) catalyze the fission of cellular membranes during budding of membrane away from the cytosol.
Shilpa Gupta, Josh Bromley, Saveez Saffarian   +2 more
doaj   +1 more source

Beyond icosahedral symmetry in packings of proteins in spherical shells [PDF]

, 2017
The formation of quasi-spherical cages from protein building blocks is a remarkable self-assembly process in many natural systems, where a small number of elementary building blocks are assembled to build a highly symmetric icosahedral cage.
Fletcher, Jordan M., Linden, Noah, Liverpool, Tanniemola B., Mosayebi, Majid, Sessions, Richard B., Shoemark, Deborah K., Woolfson, Derek N.   +6 more
core   +4 more sources

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Design Concepts of Virus-Like Particle-Based HIV-1 Vaccines

Frontiers in Immunology, 2020
Prophylactic vaccines remain the best approach for controlling the human immunodeficiency virus-1 (HIV-1) transmission. Despite the limited efficacy of the RV144 trial in Thailand, there is still no vaccine candidate that has been proven successful ...
Chun-Wei Chen, Narcís Saubi, Narcís Saubi, Joan Joseph-Munné, Joan Joseph-Munné, Joan Joseph-Munné   +5 more
doaj   +1 more source

Neuraminidase in Virus-like Particles Contributes to the Protection against High Dose of Avian Influenza Virus Challenge Infection

Pathogens, 2021
Neuraminidase is an important target for influenza vaccination. In this study, we generated avian influenza VLPs, expressing hemagglutinin (HA), neuraminidase (NA), HA and NA co-expressed (HANA), to evaluate the protective role of NA against a high ...
Hae-Ji Kang, Ki-Back Chu, Keon-Woong Yoon, Gi-Deok Eom, Jie Mao, Min-Ju Kim, Su-Hwa Lee, Eun-Kyung Moon, Fu-Shi Quan   +8 more
doaj   +1 more source

Viral Evolution and Adaptation as a Multivariate Branching Process

, 2013
In the present work we analyze the problem of adaptation and evolution of RNA virus populations, by defining the basic stochastic model as a multivariate branching process in close relation with the branching process advanced by Demetrius, Schuster and ...
Antoneli, Fernando, Bosco, Francisco, Castro, Diogo, Janini, Luiz Mário Ramos, Mondaini, R. P.   +4 more
core   +1 more source

Influenza virus-like particle vaccines

Expert Review of Vaccines, 2009
Enveloped virus-like particle (VLP) vaccines containing influenza hemagglutinin (HA) and neuraminidase (NA) antigens are produced easily in insect or mammalian cells via the simultaneous expression of HA and NA along with a viral core protein, such as influenza matrix (M1) or a retroviral Gag protein.
openaire   +2 more sources