Results 201 to 210 of about 203,768 (257)

Transcutaneous vaccination with virus-like particles

Vaccine, 2006
Virus-like particles (VLP) are inert, empty capsids of viruses, which contain no DNA/RNA from the virus itself. However they retain the structure of a virus and they can be engineered to have antigens attached. We have constructed VLP, derived from Rabbit hemorrhagic disease virus, and shown they are highly immunogenic.
Sarah L Young   +2 more
exaly   +4 more sources

Virus-like Particles: Measures and Biological Functions

open access: yesViruses, 2022
Virus-like particles resemble infectious virus particles in size, shape, and molecular composition; however, they fail to productively infect host cells.
Tara Bhat, John Yin, Yin John
exaly   +3 more sources

Virus-like particles as immunogens

Trends in Microbiology, 2003
Subunit vaccines based on recombinant proteins can suffer from poor immunogenicity owing to incorrect folding of the target protein or poor presentation to the immune system. Virus-like particles (VLPs) represent a specific class of subunit vaccine that mimic the structure of authentic virus particles.
Rob, Noad, Polly, Roy
openaire   +2 more sources

Virus-like particles in leukaemia

Experimental pathology, 1984
Hitherto intracytoplasmic virus-like particles have not been observed simultaneously in nucleus and cytoplasm in human lymphoblasts. We analysed 20 cases of lymphoblastic leukaemia in children and found some virus-like particles in cytoplasm (12 cases) and both in nucleus and cytoplasm (4 cases).
T, Slubowski, M, Kujawa
openaire   +2 more sources

Bioengineering virus‐like particles as vaccines

Biotechnology and Bioengineering, 2013
ABSTRACTVirus‐like particle (VLP) technology seeks to harness the optimally tuned immunostimulatory properties of natural viruses while omitting the infectious trait. VLPs that assemble from a single protein have been shown to be safe and highly efficacious in humans, and highly profitable.
Lua, Linda H. L.   +5 more
openaire   +5 more sources

Recent Progress on the Versatility of Virus-Like Particles

open access: yesVaccines, 2020
Virus-like particles (VLPs) are multimeric nanostructures composed of one or more structural proteins of a virus in the absence of genetic material. Having similar morphology to natural viruses but lacking any pathogenicity or infectivity, VLPs have ...
Ciying Qian, Xinlin Liu, Tingting Li
exaly   +3 more sources

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