Results 31 to 40 of about 599,985 (268)

Anti-RNA virus activity of polyoxometalates

open access: yesBiomedicine & Pharmacotherapy, 2006
The anti-RNA virus activity of polyoxometalates (POM) is reviewed, with a special emphasis on the anti-respiratory virus activities. There are many causative agents of acute viral respiratory infections; and it is rather difficult to identify the relevant agent in a given case by rapid clinical means.
Shiroh Shigeta   +4 more
openaire   +2 more sources

Interferon-beta pretreatment of conventional and plasmacytoid human dendritic cells enhances their activation by influenza virus. [PDF]

open access: yesPLoS Pathogens, 2008
Influenza virus produces a protein, NS1, that inhibits infected cells from releasing type I interferon (IFN) and blocks maturation of conventional dendritic cells (DCs).
Hannah Phipps-Yonas   +4 more
doaj   +1 more source

Map3k14 as a Regulator of Innate and Adaptive Immune Response during Acute Viral Infection

open access: yesPathogens, 2020
The replication of virus in secondary lymphoid organs is crucial for the activation of antigen-presenting cells. Balanced viral replication ensures the sufficient availability of antigens and production of cytokines, and both of which are needed for ...
Thamer A. Hamdan   +10 more
doaj   +1 more source

Endosymbiotic RNA virus inhibits Leishmania-induced caspase-11 activation

open access: yesiScience, 2021
Summary: New World species of the intracellular protozoan parasites of the Leishmania genus can cause mucocutaneous leishmaniases. The presence of an endosymbiotic Leishmania RNA virus (LRV) in Leishmania guyanensis (L.g.) promotes disease exacerbation ...
Renan V.H. de Carvalho   +3 more
doaj   +1 more source

Activation of TLR4 by viral glycoproteins: A double-edged sword?

open access: yesFrontiers in Microbiology, 2022
Recognition of viral infection by pattern recognition receptors is paramount for a successful immune response to viral infection. However, an unbalanced proinflammatory response can be detrimental to the host.
Emily A. Halajian   +3 more
doaj   +1 more source

Virus-based vaccine vectors with distinct replication mechanisms differentially infect and activate dendritic cells

open access: yesnpj Vaccines, 2021
The precise mechanism by which many virus-based vectors activate immune responses remains unknown. Dendritic cells (DCs) play key roles in priming T cell responses and controlling virus replication, but their functions in generating protective immunity ...
Carolina Chiale   +3 more
doaj   +1 more source

Chronic active varicella zoster virus infection [PDF]

open access: yesNeurology, 2012
This case report illustrates previously undescribed features of chronic active varicella zoster virus (VZV) infection, including a 4-month delay between the onset of zoster and zoster sine herpete, involvement of 9 dermatomes on progression of zoster to zoster sine herpete, and the presence of both VZV DNA and anti-VZV immunoglobulin G (IgG) in the CSF.
James, Wolf   +5 more
openaire   +2 more sources

Human Pegivirus Type 1: A Common Human Virus That Is Beneficial in Immune-Mediated Disease?

open access: yesFrontiers in Immunology, 2022
Two groups identified a novel human flavivirus in the mid-1990s. One group named the virus hepatitis G virus (HGV) and the other named it GB Virus type C (GBV-C).
Jack T. Stapleton, Jack T. Stapleton
doaj   +1 more source

Adjunctive Therapeutic Plasma Exchange in Refractory Adult‐Onset Still's Disease Complicated by Secondary Macrophage Activation Syndrome: A Single‐Center Experience

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Adult‐onset Still's disease (AOSD) complicated by macrophage activation syndrome (MAS) carries substantial mortality. The role of therapeutic plasma exchange (TPE) remains uncertain. Methods We retrospectively analyzed patients with AOSD‐MAS treated with TPE at a single‐center.
Masataka Ueda   +15 more
wiley   +1 more source

The Chikungunya Virus nsP3 Macro Domain Inhibits Activation of the NF-κB Pathway

open access: yesViruses
The role of the chikungunya virus (CHIKV) non-structural protein 3 (nsP3) in the virus lifecycle is poorly understood. The protein comprises three domains.
Grace C. Roberts   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy