Results 221 to 230 of about 243,139 (310)
Identification of a pocket factor that is critical to Zika virus assembly. [PDF]
Nat Commun, 2020 DiNunno NM +7 more
europepmc +1 more source
Identification of a Conserved Residue of Foamy Virus Gag Required for Intracellular Capsid Assembly
, 2001 Scott W. Eastman, Maxine L. Linial
openalex +1 more source
Fine mapping and characterization of the Rous sarcoma virus Pr76gag late assembly domain [PDF]
, 1996 Yan Xiang +3 more
openalex +1 more source
Advanced Science, EarlyView.Phosphorylation of Optineurin by TBK1 induces the formation of filaments that condensate upon binding to linear polyubiquitin. Membrane‐anchored LC3 partitions into these condensates, suggesting that phase separation of filamentous Optineurin with ubiquitylated cargo promotes the sequestration of cargo and its subsequent alignment with LC3‐positive ...
Maria G. Herrera +10 more
wiley +1 more source
Identification of a critical role for ZIKV capsid α3 in virus assembly and its genetic interaction with M protein. [PDF]
PLoS Negl Trop DisJablunovsky A, Narayanan A, Jose J.
europepmc +1 more source
Lactylation‐Driven YTHDC1 Alleviates MASLD by Suppressing PTPN22‐Mediated Dephosphorylation of NLRP3
Advanced Science, EarlyView.In MASLD, YTHDC1 undergoes increased lactylation and ubiquitination, reducing its expression. AARS1 mediates lactylation at lysine 565, while disrupted binding to LDHA further promotes lactylation, suppressing YTHDC1. This downregulation enhances PTPN22 mRNA stability, leading to NLRP3 dephosphorylation and activation, which exacerbates inflammation ...
Feng Zhang +16 more
wiley +1 more source
Advanced Science, EarlyView.By profiling the spatiotemporal hepatic landscape of CHB mouse models, the originally peri‐portal localized KCs migrated to the peri‐central in a CXCL9‐CXCR3‐dependent manner, facilitating their interaction with HBV+ hepatocytes. The interaction promoted LMD in KCs through ASGR1‐induced LXRα degradation, which, in turn, induced CSC formation via Stat3 ...
Jingqi Shi +18 more
wiley +1 more source
Cryo-ET of infected cells reveals that a succession of two lattices drives vaccinia virus assembly
, 2022 Hernandez-Gonzalez M +4 more
europepmc +1 more source
Advanced Science, EarlyView.This study finds that CD8⁺ TSCM cells exhibit superior self‐renewal, differentiation, and antiviral activity. Transcriptome and epigenome analyses highlight MAPK cascade regulation in TSCM cells. In vivo, virus‐specific TSCM cells show enhanced persistence and tumor protection.
Xun‐Hong Cao +13 more
wiley +1 more source