Results 11 to 20 of about 294,058 (261)
Targeting Surveillance for Zoonotic Virus Discovery
Emerging Infectious Diseases, 2013 We analyzed a database of mammal–virus associations to ask whether surveillance targeting diseased animals is the best strategy to identify potentially zoonotic pathogens.
Jordan Levinson +6 more
doaj +3 more sources
Evolving strategies for virus discovery. [PDF]
Microb GenomViruses interact with all domains of life and play fundamental roles in shaping biological systems from individual hosts to global ecosystems. Yet their identification remains difficult due to a lack of a universal marker gene and the extensive diversity of viral genomes.
Araujo Serrao de Andrade A +3 more
europepmc +2 more sources
Plant Virus Metagenomics: Advances in Virus Discovery [PDF]
Phytopathology®, 2015 In recent years plant viruses have been detected from many environments, including domestic and wild plants and interfaces between these systems—aquatic sources, feces of various animals, and insects. A variety of methods have been employed to study plant virus biodiversity, including enrichment for virus-like particles or virus-specific RNA or DNA ...
Roossinck, Marilyn J. +2 more
openaire +3 more sources
Pathogens and Passengers: Roles for Crustacean Zooplankton Viruses in the Global Ocean
Microorganisms, 2023 Viruses infect all living organisms, but the viruses of most marine animals are largely unknown. Crustacean zooplankton are a functional lynchpin in marine food webs, but very few have been interrogated for their associated viruses despite the profound ...
Alastair J. Roberts, Curtis A. Suttle
doaj +1 more source
Zika Virus Replicons for Drug Discovery [PDF]
EBioMedicine, 2016 The current epidemic of Zika virus (ZIKV) has underscored the urgency to establish experimental systems for studying viral replication and pathogenesis, and countermeasure development. Here we report two ZIKV replicon systems: a luciferase replicon that can differentiate between viral translation and RNA synthesis; and a stable luciferase replicon ...
Xie, Xuping +7 more
openaire +4 more sources
Lethal Encephalitis of Unknown Origin—Elucidation by Metagenomics
Proceedings, 2020 Novel and (re)emerging viruses cause frequent threats to both human and animal health. Diagnostic metagenomics using unbiased next-generation sequencing (NGS) is the key method for the identification of new pathogens.
Martin Beer
doaj +1 more source
No Evidence of Ntwetwe Virus Infections in Children Presenting to Kiboga Hospital, Uganda
Tropical Medicine and Infectious Disease, 2022 We investigated whether Ntwetwe virus—a novel orthobunyavirus discovered in a Ugandan girl with a fatal encephalopathy—was a common reason for hospital admission for children to Kiboga hospital, Uganda. A case–control was conducted between September 2019
Arthur W. D. Edridge +10 more
doaj +1 more source
Metagenomics in virus discovery [PDF]
ISBT Science Series, 2013 Virus infections are a continuous threat to the human population. Apart from infections with known viruses, there is a world of yet unknown viruses which may cause new emerging diseases, or cause known infectious diseases. Discovery of unknown viruses requires serious efforts since there is no universal viral genomic sequence to amplify an unknown ...
S. M. Jazaeri Farsani +4 more
openaire +1 more source
Viruses, 2020 The Asian tiger mosquito Aedes albopictus is a competent vector for several human arboviruses including dengue, chikungunya and Zika viruses. Mosquitoes also harbor insect-specific viruses (ISVs) that may modulate host physiology and potentially affect ...
Mosè Manni, Evgeny M. Zdobnov
doaj +1 more source
Viruses, 2021 Rubella virus (RuV) is the causative agent of rubella (“German measles”) and remains a global health concern. Until recently, RuV was the only known member of the genus Rubivirus and the only virus species classified within the Matonaviridae family of ...
Rebecca M. Grimwood +2 more
doaj +1 more source