Results 71 to 80 of about 258,080 (265)

Infection Dynamics and Coexistence of Two Novel Arctic Phytoplankton Viruses

Viruses
Marine algal viruses exhibit a high level of diversity, and closely related viruses targeting the same algal host species can stably coexist. Here we report an example of a single virus–host system concealing hidden complexity.
Claudia Meyer, Victoria L. N. Jackson, Floris de Haan, Henk Bolhuis, Michael J. Allen, Adam Monier, Corina P. D. Brussaard   +6 more
doaj   +1 more source

Wide Diversity of Coronaviruses in Frugivorous and Insectivorous Bat Species: A Pilot Study in Guinea, West Africa

Viruses, 2020
Zoonoses can constitute a threat for public health that can have a global importance, as seen with the current COVID-19 pandemic of severe acute respiratory syndrome coronavirus (SARS-CoV2). Bats have been recognized as an important reservoir of zoonotic
Audrey Lacroix, Nicole Vidal, Alpha K. Keita, Guillaume Thaurignac, Amandine Esteban, Hélène De Nys, Ramadan Diallo, Abdoulaye Toure, Souana Goumou, Abdoul Karim Soumah, Moriba Povogui, Joel Koivogui, Jean-Louis Monemou, Raisa Raulino, Antoine Nkuba, Vincent Foulongne, Eric Delaporte, Ahidjo Ayouba, Martine Peeters   +18 more
doaj   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Plant Virus Diversity and Evolution

, 2016
Historically, the majority of plant virology focused on agricultural systems. Recent efforts have expanded our knowledge of the true diversity of plant viruses by studying those viruses that infect wild, undomesticated plants. Those efforts have provided answers to basic ecological questions regarding viruses in the wild, and insights into evolutionary
Stobbe, Anthony, Roossinck, Marilyn J.
openaire   +1 more source

A Tutorial Toolbox to Simplify Bioinformatics and Biostatistics Analyses of Microbial Omics Data in an Island Context

BioMedInformatics
Background: Bioinformatics is increasingly used in various scientific works. Large amounts of heterogeneous data are being generated these days. It is difficult to interpret and analyze these data effectively.
Isaure Quétel, Sourakhata Tirera, Damien Cazenave, Nina Allouch, Chloé Baum, Yann Reynaud, Degrâce Batantou Mabandza, Virginie Nerrière, Serge Vedy, Matthieu Pot, Sébastien Breurec, Anne Lavergne, Séverine Ferdinand, Vincent Guerlais, David Couvin   +14 more
doaj   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source

Unlocking the potential of cell‐permeable nanobodies for intracellular applications

FEBS Letters, EarlyView.
This review outlines current strategies for delivery of nanobodies into cells and highlights recent examples of functional applications. By addressing and manipulating intracellular targets, these molecules hold great potential for treating cancer, respiratory diseases and neurological disorders, making this a vibrant area of research in the biomedical
Mariona Gené‐Verdés, Luise Franz, Christian P.R. Hackenberger   +2 more
wiley   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Increased Diversity of Citrus Tristeza Virus in Europe

Plant Disease
This study investigated the genetic diversity of Citrus tristeza virus (CTV) isolates from Montenegro and Croatia, European countries with the northernmost citrus-growing regions situated on the Eastern Adriatic coast. Fifteen complete or nearly complete CTV genomes were reconstructed by high-throughput sequencing of samples collected in distinct ...
Jelena Zindović, Miroslav Čizmović, Ana Vučurović, Paolo Margaria, Dijana Škorić   +4 more
openaire   +4 more sources

Viral diversity of Junín virus field strains

Virus Research, 2011
The Argentine Hemorrhagic Fever, an endemic disease present in a much of Argentina, is caused by the Junín virus (JUNV). Currently, there are sequences available from several strains of this virus, like those belonging to the vaccine lineage (XJ13, XJ#44 and Candid#1), as well as MC2 (rodent isolate) and IV4454 (human isolate).
Goñi, Sandra Elizabeth, Stephan, Betina Inés, Iserte, Javier Alonso, Contigiani de Minio, Marta Silvia, Lozano, Mario Enrique, Antonio Tenorio   +5 more
openaire   +3 more sources