Results 81 to 90 of about 263,373 (311)

Metatranscriptome-based strategy reveals the existence of novel mycoviruses in the plant pathogenic fungus Fusarium oxysporum f. sp. cubense

Frontiers in Microbiology, 2023
Fusarium oxysporum f. sp. cubense (Foc) is a devastating plant pathogen that caused a great financial loss in the banana’s source area. Metatranscriptomic analysis was used to determine the diversity of mycoviruses in 246 isolates of F. oxysporum f.
Yiting Ye, Yingying Liu, Yifei Zhang, Xin Wang, Huaping Li, Pengfei Li   +5 more
doaj   +1 more source

The transmission dynamics of groups A and B human respiratory syncytial virus (hRSV) in England & Wales and Finland: seasonality and cross-protection [PDF]

, 2005
Human respiratory syncytial virus (hRSV) transmission dynamics are inherently cyclical, and the observed genetic diversity (between groups A and B) also appears to have a repeating pattern.
Waris, M, White, Lisa, Medley, GF, White, L. J., Medley, Graham, Waris, M., Cane, Patricia, Nokes, D. James, Nokes, DJ, White, LJ, Cane, PA   +10 more
core   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Geographical and chronological origin and evolution of Hepatitis C Virus.

, 2011
Hepatitis C Virus (HCV) infection is a major health problem that leads to cirrhosis and hepatocellular carcinoma. World over, more than 270-300 million people are estimated to be infected with the virus.
Sugunan V.S., amjesh revikumar, Achuthsankar S. Nair   +2 more
core   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Sequence diversity of hepatitis D virus in Mongolia

Frontiers in Medicine, 2023
IntroductionThe Hepatitis Delta Virus (HDV) is a defective, single-stranded RNA virusoid encoding for a single protein, the Hepatitis Delta Antigen (HDAg), which requires the hepatitis B virus (HBV) envelope protein (HBsAg) for its transmission. Currently, hepatitis D is the most aggressive form of viral hepatitis and treatment options are limited ...
Battur Magvan, Anne Alina Kloeble, Johannes Ptok, Daniel Hoffmann, Daniel Habermann, Anuujin Gantumur, Martha Paluschinski, Gerelmaa Enebish, Vera Balz, Johannes C. Fischer, Battogtokh Chimeddorj, Battogtokh Chimeddorj, Andreas Walker, Jörg Timm   +13 more
openaire   +4 more sources

Global distributions and strain diversity of avian infectious bronchitis virus: a review [PDF]

, 2017
The poultry industry faces challenge amidst global food security crisis. Infectious bronchitis is one of the most important viral infections that cause huge economic loss to the poultry industry worldwide. The causative agent, infectious bronchitis virus
Mahmuda, Aliyu, Venugopal Nair, Omar, Abdul Rahman, Bejo, Mohd Hair, Mohd Hair-Bejo, Bande, Faruku, Abdul Rahman Omar, Aliyu Mahmuda, Arshad, Siti Suri, Siti Suri Arshad, Nair, Venugopal, Faruku Bande   +11 more
core   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Metagenomic and whole-genome analysis reveals new lineages of gokushoviruses and biogeographic separation in the sea

Frontiers in Microbiology, 2013
Much remains to be learned about single-stranded (ss) DNA viruses in natural systems, and the evolutionary relationships among them. One of the eight recognized families of ssDNA viruses is the Microviridae, a group of viruses infecting bacteria. In this
Jessica Myriam Labonté, Jessica Myriam Labonté, Curtis A Suttle, Curtis A Suttle, Curtis A Suttle, Curtis A Suttle   +5 more
doaj   +1 more source

Investigation of denugue virus envelope gene quasispecies variation in patient samples : implications for virus virulence and disease pathognesis [PDF]

, 2011
Due to the error-prone nature of RNA virus replication, each dengue virus (DV) exists as a quasispecies within the host. To investigate the hypothesis that DV quasispecies populations affect disease severity, serum samples were obtained from dengue ...
Love, Hannah
core