Results 251 to 260 of about 2,750,709 (301)

NeuroSuite for Long‐Term Functional and Structural Studies of Air‐Liquid Interface Cerebral Organoids

Advanced Science, EarlyView.
NeuroSuite provides a modular hardware‐software platform integrating Neuroweb and NeuroMaps to enable long‐term, in situ electrophysiological interrogation of air–liquid interface organoid slices while preserving tissue architecture. Its components can be used together or independently to capture real‐time activity, spatial network dynamics, and ...
Belquis Haider, Sagnik Middya, Daniel J. Lloyd‐Davies‐Sánchez, Nino F. Läubli, Sulay Vora, Jakob Träuble, Rohan N. Krajeski, Yuqing Feng, Daniel Duncko, Josiah S. Riley, Rubén Ruiz‐Mateos Serrano, Ole Paulsen, Madeline A. Lancaster, George G. Malliaras, Gabriele S. Kaminski Schierle   +14 more
wiley   +1 more source

Early Transcriptomic Response of Human Iris Stromal Cells During Herpes Simplex Virus Entry Reveals Interplay Between Cell Glycocalyx and Viral Exploitation. [PDF]

Int J Mol Sci
Elste J, Zanotti B, Schnurr M, Papanikolas MJ, Stephenson EJ, Swanson-Mungerson M, Volin MV, Freeman R, Tiwari V.   +8 more
europepmc   +1 more source

BAP31 Drives Cartilage Calcification through Disruption of Autophagosome–Lysosome Fusion in Osteoarthritis

Advanced Science, EarlyView.
Mechanical stress activates BAP31 in chondrocytes. BAP31 competes with ATG14 for binding to STX17, disrupting the STX17–ATG14 complex required for autophagosome–lysosome fusion. The resultant autophagic flux blockade drives the generation of autophagy‐derived exosomes, which mediate pathological cartilage calcification in OA. Chondrocyte‐targeted BAP31
Zhi‐hua Xu, Ruo‐xin Wang, Feng He, Qian Liu, Fu‐yin Li, Min Hui, Yu‐qian Shi, Yu Jiang, Qing‐hua Li, Jun‐wen Jing, Shi‐bin Yu, Li‐tian Ma, Qian‐nan Niu, Mian Zhang   +13 more
wiley   +1 more source

In Silico Redesign of Epstein-Barr Virus Entry Glycoproteins to Redirect Cellular Tropism as a Foundation for a Novel B Cell Oncolytic Therapy. [PDF]

Cureus
Ahluwalia J, Katakam A, Satish S.
europepmc   +1 more source

Transcription Factor Promiscuity Drives Regulatory Rewiring and Evolvability in Gene Networks in Bacteria

Advanced Science, EarlyView.
When a master transcription factor (TF) is lost, bacteria can rapidly rewire gene regulatory networks by co‐opting related regulators. Using experimental evolution in Pseudomonas fluorescens, we show that TF promiscuity (low‐level, non‐cognate binding) provides the raw material for rewiring. Successful co‐option follows a predictable hierarchy governed
Tiffany B. Taylor, Alan M. Rice
wiley   +1 more source

Cellular SLC35B4 promotes internalization during influenza A virus entry. [PDF]

mBio
Wang G, Jiang L, Yan Y, Kong F, Li Q, Zhang J, Hou S, Wang B, Wang X, Kong H, Deng G, Shi J, Tian G, Zeng X, Chen H, Li C.   +15 more
europepmc   +1 more source

ICAM-1-mediated Src signaling pathway plays a pivotal role in encephalomyocarditis virus entry. [PDF]

J Virol
Lian R, Dou X, Wang N, Li S, Xie J, Li X, Yang Y, Wen Y, Li H, Feng R.   +9 more
europepmc   +1 more source

The Virus Entry Pathway Determines Sensitivity to the Antiviral Peptide TAT-I24. [PDF]

Viruses
Kicker E, Kouros A, Zatloukal K, Harant H.   +3 more
europepmc   +1 more source

Hepatitis B virus entry, assembly, and egress. [PDF]

Microbiol Mol Biol Rev
Chuang Y-C, Ou J-HJ.
europepmc   +1 more source