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Parainfluenza virus entry at the onset of infection

2021
Parainfluenza viruses, members of the enveloped, negative-sense, single stranded RNA Paramyxoviridae family, impact global child health as the cause of significant lower respiratory tract infections. Parainfluenza viruses enter cells by fusing directly at the cell surface membrane. How this fusion occurs via the coordinated efforts of the two molecules
Tara C, Marcink   +2 more
openaire   +2 more sources

Zika virus entry inhibitors

Bioorganic & Medicinal Chemistry
Viral entry step involves of complex host-virus interactions. Research progress of viral entry inhibitors lags significantly behind that of viral replication inhibitors targeting viral non-structural proteins. Here we take Zika virus (ZIKV), a neglected flavivirus currently lacking effective therapeutic drugs, as an example of enveloped RNA viruses to ...
Weiyi, Yin   +3 more
openaire   +2 more sources

Mechanisms of cell entry by influenza virus

Expert Reviews in Molecular Medicine, 2001
A wide range of viruses, including many human and animal pathogens representing various taxonomic groups, contain genomes that are enclosed in lipid envelopes. These envelopes are generally acquired in the final stages of assembly, as viruses bud from regions of the membrane of the infected cell at which virally encoded membrane proteins have ...
K J, Cross   +2 more
openaire   +2 more sources

Virus Entry and Innate Immune Activation

2008
Human cytomegalovirus (HCMV) exhibits an exceptionally broad cellular tropism as it is capable of infecting most major organ systems and cell types. Definitive proof of an essential role for a cellular molecule that serves as an entry receptor has proven very challenging.
M K, Isaacson, L K, Juckem, T, Compton
openaire   +2 more sources

Virus entry pathways

2012
To deliver tehir genetic material and accessory proteins, viruses must enter host cells. Endocytosis provides viruses this opportunity. However, endocytosis is a complex process that includes several distinct pathways, such as clathrin-mediated endocytosis, caveolin-mediated endocytosis, macropinocytosis, and phagocytosis.
MOTTOLA, GIOVANNA, E. Ghigo
openaire   +1 more source

Lessons in self-defence: inhibition of virus entry by intrinsic immunity

Nature Reviews Immunology, 2021
Saliha Majdoul, Alex A Compton
exaly  

Cervical cancer prevention and control in women living with human immunodeficiency virus

Ca-A Cancer Journal for Clinicians, 2021
Vikrant V Sahasrabuddhe   +2 more
exaly  

The oncologic burden of hepatitis C virus infection: A clinical perspective

Ca-A Cancer Journal for Clinicians, 2017
Felipe Samaniego   +2 more
exaly  

The ins and outs of hepatitis C virus entry and assembly

Nature Reviews Microbiology, 2013
Charles M. Rice, Brett Lindenbach
exaly  

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