Results 51 to 60 of about 2,624 (181)
Application of multiplex realtime PCR detection for hemorrhagic fever syndrome viruses
Journal of Infection and Public Health, 2023 Background: Multiplex real-time PCR is a quick and cost effective method for detection of various gene simultaneously. HFSV (Hemorrhagic Fever Syndrome Virus) is a newly emerging infectious disease because of globalization and climate change. We tried to
Yoonhyuk Choi, Younghee Kim
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Journal of Biochemical and Molecular Toxicology, Volume 39, Issue 6, June 2025.ABSTRACT Favipiravir is a selective RNA polymerase inhibitor and a broad‐spectrum antiviral drug. Favipiravir reduces cell proliferation by inhibiting RNA transcription, particularly in rapidly proliferating cells such as spermatogonia. The aim of this study was to investigate the effects and mechanism of action of favipiravir (T‐705) on sperm quality ...
Ali Doğan Ömür +6 more
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Nipah Virus Infection Generates Ordered Structures in Cellulo
Viruses, 2022 Nipah virus (NiV) is a zoonotic paramyxovirus with a fatality rate of up to 92% in humans. While several pathogenic mechanisms used by NiV to counteract host immune defense responses have been described, all of the processes that take place in cells ...
Cecilia Alejandra Vázquez +12 more
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Protection Conferred against Junin Virus Infection in Rats
Intervirology, 1984 2-day-old Wistar rats intracerebrally infected with the XJC13 strain of virus exhibited a 5% survival rate which rose to 71% after immune serum treatment. Brain viral titers were relatively unaffected by this treatment. Histologic studies showed necrosis in the cerebellum and brain cortex with mononuclear cell infiltration in both treated and ...
J L, Blejer +3 more
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WIREs RNA, Volume 16, Issue 2, March/April 2025.Stress granules emerging during viral infection can play both pro‐ and antiviral roles. RNA viruses use various strategies to antagonize their formation, including the degradation, inhibition, or sequestration of G3BP1, a key stress granule protein. However, biochemical and structural insights into these mechanisms have been reported for only a handful
Moh Egy Rahman Firdaus +3 more
wiley +1 more source
Журнал микробиологии, эпидемиологии и иммунобиологии, 2015 Aim. Experience of study and possible ways of elimination of false positive and false negative results during execution of polymerase chain reaction on an example of Junin virus RNA detection. Materials and methods.
T. E Sizikova +4 more
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Frontiers in Immunology, 2019 The New World arenavirus Junin (JUNV) is the etiological agent of Argentine hemorrhagic fever (AHF). Previous studies of human macrophage infection by the Old-World arenaviruses Mopeia and Lassa showed that while the non-pathogenic Mopeia virus ...
María F. Ferrer +12 more
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Exploring the druggability of the UEV domain of human TSG101 in search for broad‐spectrum antivirals
Protein Science, Volume 34, Issue 1, January 2025.Abstract The ubiquitin E2 variant domain of TSG101 (TSG101‐UEV) plays a pivotal role in protein sorting and virus budding by recognizing PTAP motifs within ubiquitinated proteins. Disruption of TSG101‐UEV/PTAP interactions has emerged as a promising strategy for the development of host‐oriented broad‐spectrum antivirals with low susceptibility to ...
Fernando Montero +17 more
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Activation of the STAT3 Signaling Pathway by the RNA-Dependent RNA Polymerase Protein of Arenavirus
Viruses, 2021 Arenaviruses cause chronic and asymptomatic infections in their natural host, rodents, and several arenaviruses cause severe hemorrhagic fever that has a high mortality in infected humans, seriously threatening public health.
Qingxing Wang +5 more
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Advances in Pharmacological and Pharmaceutical Sciences, Volume 2025, Issue 1, 2025.Due to its intricacy and long‐term usefulness, traditional medicine continues to be practiced in several nations. Among the many medicinal plants found in the Dhofar region of Oman, the aromatic oleo‐gum resin generated by Boswellia sacra, commonly referred to as frankincense, stands out for its medical and commercial significance. Resin‐carrying ducts
Foziya Khan, Luay Rashan, Kuldeep Singh
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