Results 101 to 110 of about 75,185 (247)

Molecular Basis of Epstein-Barr Virus Latency Establishment and Lytic Reactivation. [PDF]

Viruses, 2021
Murata T, Sugimoto A, Inagaki T, Yanagi Y, Watanabe T, Sato Y, Kimura H.   +6 more
europepmc   +1 more source

Multidimensional and Multifunctional Laser‐Induced Graphene (LIG) for Point‐of‐Care and Wearable Biosensing, Theranostics, and Bioactive Interfaces Toward Personalized Healthcare and Regenerative Medicine

Advanced Science, EarlyView.
Multidimensional laser‐induced graphene (LIG) spanning from 0D to 3D architectures is comprehensively reviewed for multifunctional biomedical platforms, including biosensing, theranostics, and bioactive interface applications, which highlights its potentials for point‐of‐care diagnostics, wearable health monitoring, smart drug delivery, and tissue ...
Li Zhang, Yurou Yuan, Xiaohong Ding, Wing Cheung Mak   +3 more
wiley   +1 more source

Purging viral latency by a bifunctional HSV-vectored therapeutic vaccine in chronically SIV-infected macaques

eLife
The persistence of latent viral reservoirs remains the major obstacle to eradicating human immunodeficiency virus (HIV). We herein found that ICP34.5 can act as an antagonistic factor for the reactivation of HIV latency by herpes simplex virus type I ...
Ziyu Wen, Pingchao Li, Yue Yuan, Congcong Wang, Minchao Li, Haohang Wang, Minjuan Shi, Yizi He, Mingting Cui, Ling Chen, Caijun Sun   +10 more
doaj   +1 more source

MLL1 is regulated by KSHV LANA and is important for virus latency. [PDF]

Nucleic Acids Res, 2021
Tan M, Li S, Juillard F, Chitas R, Custódio TF, Xue H, Szymula A, Sun Q, Liu B, Álvarez ÁL, Chen S, Huang J, Simas JP, McVey CE, Kaye KM.   +14 more
europepmc   +1 more source

A Dual‐Functional Biohybrid Nanorobot to Synergistically Eradicate Biofilm and Degrade Antibiotic Resistance Genes

Advanced Science, EarlyView.
A biohybrid nanorobot integrating lytic bacteriophage N4 with Pd nanozymes is developed for targeted eradication of multidrug‐resistant E. coli biofilms. Synergistic bacterial lysis and ROS‐mediated oxidation enable simultaneous biofilm removal and antibiotic resistance genes degradation, maintaining high efficacy in complex wastewater environments ...
Junzheng Zhang, Tong Dou, Luokai Wang, Jingxian Yang, Wenrui Wang, Shuaitian Guo, Xiangyu Li, Xuefang Huang, Yunlei Xianyu, Dongsheng Wang   +9 more
wiley   +1 more source

DLK-Dependent Biphasic Reactivation of Herpes Simplex Virus Latency Established in the Absence of Antivirals. [PDF]

J Virol, 2022
Dochnal S, Merchant HY, Schinlever AR, Babnis A, Depledge DP, Wilson AC, Cliffe AR.   +6 more
europepmc   +1 more source

Paternal Caffeine Exposure Programs Offspring Stress Vulnerability via Sperm Dlk1‐Dio3 Imprinting‐Directed Remodeling of a Novel Neural Circuit

Advanced Science, EarlyView.
The study elucidates that paternal preconception stress can drive offspring hyperresponsivity of the stress system via hypomethylation of a specific DNA region in sperm. This key link is confirmed in a cohort of prospective fathers: the epigenetic alteration is associated with elevated stress hormone levels.
Mengxi Lu, Gaole Dai, Sen Zhu, Shuai Zhang, Tingting Wang, Yuan Meng, Fang Yang, Xiaoyi Han, Hui Wang, Hao Kou, Dan Xu   +10 more
wiley   +1 more source

Retraction: ‘RNA editing of microRNA prevents RNA-induced silencing complex recognition of target mRNA’ (2015), by Cui et al.

Open Biology, 2023
doaj   +1 more source

The anti-apoptotic function of HSV-1 LAT in neuronal cell cultures but not its function during reactivation correlates with expression of two small non-coding RNAs, sncRNA1&2.

PLoS Pathogens
Multiple functions are associated with HSV-1 latency associated transcript (LAT), including establishment of latency, virus reactivation, and antiapoptotic activity.
Jay J Oh, Ujjaldeep Jaggi, Kati Tormanen, Shaohui Wang, Satoshi Hirose, Homayon Ghiasi   +5 more
doaj   +1 more source

Marek’s disease virus-encoded microRNA-M6-5p facilitates viral latent infection by targeting histone demethylase KDM2B

Journal of Virology
Marek’s disease virus (MDV), a highly contagious and oncogenic avian alphaherpesvirus, establishes a latent infection primarily in CD4+ T cells. Latent infections are necessary for both persistent lifelong MDV infection and viral tumorigenesis. MicroRNAs
Linyi Zhou, Runan Zhu, Bo Jiang, Jing Cheng, Wenxiao Liu, Yongxiu Yao, Yongqing Li   +6 more
doaj   +1 more source