Results 91 to 100 of about 309,484 (272)
The Role of Intestinal Microbiota and Mast Cell in a Rat Model of Visceral Hypersensitivity
Journal of Neurogastroenterology and Motility, 2020 Background/Aims To explore the role of intestinal flora and mast cells in visceral hypersensitivity (VH). Methods The experimental animals were divided into 4 groups control group, VH group, VH + VSL#3 group, and VH + ketotifen group.
Ying-Jie Li, Jing Li, C. Dai
semanticscholar +1 more source
Neurourology and Urodynamics, EarlyView.ABSTRACT Aims While many patients with lower urinary tract symptoms (LUTS) improve by treating peripheral causes, a substantial proportion continue to experience symptoms despite apparently successful interventions. Central nervous system (CNS) mechanisms could potentially contribute to persisting symptoms after the initial peripheral cause has been ...
Mathijs M. de Rijk +7 more
wiley +1 more source
Molecular Pain, 2009 Background Visceral hypersensitivity is a clinical observation made when diagnosing patients with functional bowel disorders. The cause of visceral hypersensitivity is unknown but is thought to be attributed to inflammation.
Caudle Robert M, Suckow Shelby K
doaj +1 more source
Neuroimmune cross talk in the gut. Neuroendocrine and neuroimmune pathways contribute to the pathophysiology of irritable bowel syndrome [PDF]
, 2016 Irritable bowel syndrome (IBS) is a common disorder characterized by recurrent abdominal pain, bloating, and disturbed bowel habit, symptoms that impact the quality of life of sufferers.
O'Malley, Dervla
core +1 more source
Pediatric Discovery, EarlyView.Through network pharmacology and molecular docking, it has been discovered that CA can target MAOB, among other proteins, to exert a therapeutic effect in IBS. In vivo, CA lowered visceral hypersensitivity, anxiety and depression‐like behaviors, and fecal water content, highlighting its therapeutic potential for IBS via anti‐inflammatory pathways ...
Qingyang Yu +4 more
wiley +1 more source
Return to competition in a chronic low back pain runner: beyond a therapeutic exercise approach, a case report [PDF]
, 2014 Chronic low back pain (CLBP) is a disabling condition affecting both quality of life and performance in athletes. Several approaches have been proposed in the field of physiotherapy, manual therapy, physical exercise and counseling.
Castelli C.C. +4 more
core +4 more sources
The Prostate, EarlyView.ABSTRACT Background Methyl Methanesulfonate‐Sensitivity Protein 22‐Like (MMS22L) plays a key role in homology‐directed DNA repair, and experimental models have shown that its loss confers sensitivity to Poly (ADP‐ribose) polymerase inhibitors (PARPi).
Mayuko Kanayama +12 more
wiley +1 more source
Journal of Pharmacological Sciences, 2021 Visceral hypersensitivity and impaired gut barrier are crucial pathophysiology of irritable bowel syndrome (IBS), and injection of lipopolysaccharide or corticotropin-releasing factor, and repeated water avoidance stress simulate these gastrointestinal ...
Tsukasa Nozu +5 more
doaj +1 more source
Towards multiple interactions of inner and outer sensations in corporeal awareness [PDF]
, 2015 Under normal circumstances, different inner- and outer-body sources are integrated to form coherent and accurate mental experiences of the state of the body, leading to the phenomenon of corporeal awareness. How these processes are affected by changes in
LUCCI, Giuliana, PAZZAGLIA, Mariella
core +1 more source
Evidence-Based Complementary and Alternative Medicine, 2020 Changes in gut motility and visceral hypersensitivity are two major features of irritable bowel syndrome (IBS). Current drug treatments are often poorly efficacious, with many side effects for patients with IBS.
Bo Li +9 more
semanticscholar +1 more source