Results 81 to 90 of about 21,147 (220)
Paneth cell defects induce microbiota dysbiosis In mice and promote visceral hypersensitivity [PDF]
, 2017 Separation of newborn rats from their mothers induces visceral hypersensitivity and impaired epithelial secretory cell lineages when they are adults. Little is known about the mechanisms by which maternal separation causes visceral hypersensitivity or ...
Marion Gillet +31 more
core +1 more source
The Role of Polyphenols in Respiratory and Gut Health: From the Perspective of Gut‐Lung Axis
Phytotherapy Research, EarlyView.ABSTRACT The gut‐lung axis constitutes a dynamic, multidirectional communication platform between the gastrointestinal and respiratory tracts. Its complexity arises from the integrated crosstalk among the microbiota, immune system, and redox homeostasis, collectively influencing disease susceptibility and progression.
Jian Kang +7 more
wiley +1 more source
Novel therapeutic targets for chronic visceral pain in gastrointestinal disorders
British Journal of Pharmacology, EarlyView.Chronic visceral pain imposes a major clinical challenge in gastroenterology and beyond, profoundly impacting patients' quality of life. However, limited understanding of its complex, multifaceted pathophysiology, encompassing both peripheral and central mechanisms, continues to impede the development of effective management strategies.
Fleur Veldman +3 more
wiley +1 more source
Molecular Pain, 2009 Background Visceral hypersensitivity is a clinical observation made when diagnosing patients with functional bowel disorders. The cause of visceral hypersensitivity is unknown but is thought to be attributed to inflammation.
Caudle Robert M, Suckow Shelby K
doaj +1 more source
British Journal of Pharmacology, EarlyView.The κ opioid receptor (κ receptor, KOR) is a G protein‐coupled receptor with well established roles in analgesia and immune modulation. Although historically studied primarily in the central nervous system (CNS), growing evidence indicates that κ signalling in peripheral tissues plays an important role in regulating pain, inflammation and immune ...
Rumsha Khan +3 more
wiley +1 more source
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.Summary Background and Objectives Teledermatology has become an essential part of dermatological care, although challenges in its implementation remain. We conducted a real‐life survey on video consultations over a one‐year period to assess satisfaction and identify barriers.
Felix von Krogh +4 more
wiley +1 more source
Data_Sheet_1_Small-Conductance Ca2+-Activated K+ Channel 2 in the Dorsal Horn of Spinal Cord Participates in Visceral Hypersensitivity in Rats.docx [PDF]
, 2018 Visceral hypersensitivity is a highly complex and subjective phenomenon associated with multiple levels of the nervous system and a wide range of neurotransmission.
Si-Ting Huang (5591432) +7 more
core +1 more source
JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.Summary Background The teaching of elementary skin lesions and the ABCDE rule are central components of undergraduate medical education in dermatology. This content is typically taught using photographs, moulages, or patient examples. Independent practice under supervision, however, is often difficult to implement in everyday clinical work ...
Conrad Hempel +3 more
wiley +1 more source
Visceral hypersensitivity in Irritable Bowel Syndrome:pathophysiological mechanisms [PDF]
, 2009 Irritable Bowel Syndrome (IBS) is a functional bowel disease characterized by abdominal pain or discomfort associated with a disordered defecation. No unique pathophysiological mechanism has been identified.
Kerckhoffs, A.P.M.
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