Results 121 to 130 of about 21,147 (220)
The Dual Roles of Regulatory B Cells in Infection, Cancer, and Immunity
MedComm, Volume 7, Issue 7, July 2026.Regulatory B cells maintain immune homeostasis via suppressive cytokines and surface molecules like PD‐L1. While beneficially suppressing autoimmunity and promoting transplant tolerance, these identical mechanisms detrimentally attenuate antipathogen and antitumor immune responses.
Anni Feng +3 more
wiley +1 more source
United European Gastroenterology Journal, Volume 14, Issue 6, July 2026.ABSTRACT Background Noncoeliac gluten sensitivity (NCGS) remains a controversial clinical entity at the intersection between disorders of gut–brain interaction (DGBI) and disordered eating. We aimed to determine the prevalence of self‐reported NCGS and to characterise its association with DGBI and avoidant/restrictive food intake disorder (ARFID ...
Mohamed G. Shiha +5 more
wiley +1 more source
Emotional and Behavioural Problems in Children With Functional Gastrointestinal Disorders
Acta Paediatrica, Volume 115, Issue 7, Page 1510-1518, July 2026.ABSTRACT Aim Functional gastrointestinal disorders (FGIDs) are common in childhood, but psychological correlates remain poorly understood. We compared emotional and behavioural functioning in children with FGIDs with somatic and healthy controls. Methods Parents of children aged 2–12 years were recruited at the University Children's Hospital Basel ...
Sebastian Weber +4 more
wiley +1 more source
Alimentary Pharmacology &Therapeutics, Volume 64, Issue 2, Page 208-221, July 2026.In a cohort of IBS‐D patients recruited to the TRITON study, faecal metabolomic profiling reveals a SCFA‐enriched metabotype associated with increased pain and urgency, altered stool characteristics and accelerated intestinal transit. ABSTRACT Background Metabolomic analysis in irritable bowel syndrome (IBS) has identified metabotypes enriched in ...
T. E. Conley +8 more
wiley +1 more source
Psilocybin as a novel treatment for chronic pain
British Journal of Pharmacology, Volume 183, Issue 14, Page 3992-4005, July 2026.Abstract Psychedelic drugs are under active consideration for clinical use and have generated significant interest for their potential as anti‐nociceptive treatments for chronic pain, and for addressing conditions like depression, frequently co‐morbid with pain.
Tate Askey +3 more
wiley +1 more source
Cancer Science, Volume 117, Issue 7, Page 1985-1995, July 2026.In patients with mCSPC treated with apalutamide plus ADT, baseline ctDNA predicted earlier progression to CRPC and worse overall survival. Exploratory genome‐wide analysis identified 12 SNPs associated with apalutamide‐related skin rash. ABSTRACT Despite promising evidence of the efficacy of the androgen deprivation therapy (ADT) plus apalutamide in ...
Masaki Shiota +8 more
wiley +1 more source
Headache: The Journal of Head and Face Pain, Volume 66, Issue 7, Page 1628-1643, July/August 2026.Abstract Background Calcitonin gene‐related peptide (CGRP) is a key mediator in migraine pathophysiology, and the development of gepants, novel CGRP receptor antagonists, has expanded therapeutic options for both acute and preventive treatment. This scoping review aims to synthesize current evidence on the pharmacology, clinical applications, safety ...
Luigi Francesco Iannone +5 more
wiley +1 more source
Nature CommunicationsVisceral pain represents an unmet clinical need due to the lack of safe and generalizable therapies. Given the analgesic potential of music and the underlying crosstalk between auditory and nociceptive pathways, this study aims to delineate the neural ...
Yang Yu +7 more
doaj +1 more source
Journal of Gastroenterology and Hepatology, Volume 41, Issue 7, Page 2043-2061, July 2026.The first Australian guidance document on the assessment and management of idiopathic gastroparesis (IGP) reconceptualises IGP as a sensorimotor disorder. It proposes a novel multidisciplinary treatment algorithm and 20 high‐consensus recommendations, addressing common overlapping disorders, and providing clear guidance on associated disordered eating ...
Trina Kellar +11 more
wiley +1 more source
Neurogastroenterology &Motility, Volume 38, Issue 7, July 2026.The Auckland Classification, derived by international consensus, presents a structured framework for BSGM‐defined patient phenotypes. This classification forms a foundation for research, further validation, and a pathway for integrating BSGM into clinical care. ABSTRACT Introduction Chronic gastroduodenal disorders remain challenging to manage, and new
Chris Varghese +66 more
wiley +1 more source