Results 11 to 20 of about 309,484 (272)
Frontiers in Neuroscience, 2022 Patients with irritable bowel syndrome (IBS) experience not only enhanced visceral pain but also emotional comorbidities, such as anxiety and depression. Early life stress (ELS) is a high-risk for the development of IBS.
Le Guan +10 more
doaj +2 more sources
Frontiers in Pharmacology, 2021 Visceral hypersensitivity as a common clinical manifestation of irritable bowel syndrome (IBS) may contribute to the development of chronic visceral pain.
Si-Ting Huang +6 more
doaj +2 more sources
Clostridium butyricum relieve the visceral hypersensitivity in mice induced by Citrobacter rodentium infection with chronic stress [PDF]
PeerJ, 2021 Background Visceral hypersensitivity is a common symptom in patients with post-infectious irritable bowel syndrome (PI-IBS), and change of the microbiota is a vital etiological factor of it. Clostridium butyricum (C.
Tengfei Wang +6 more
doaj +3 more sources
Frontiers in Neuroscience, 2022 Early life stress (ELS) disposes to functional gastrointestinal diseases in adult, such as irritable bowel syndrome (IBS). Maternal separation (MS) is a well-known animal model of IBS and has been shown to induce visceral hypersensitivity in adult rats ...
Enfu Tao +8 more
doaj +2 more sources
Neural Plasticity, 2020 Background. Visceral hypersensitivity is a common occurrence of gastrointestinal diseases such as irritable bowel syndrome (IBS), wherein early-life stress (ELS) may have a high predisposition to the development of visceral hypersensitivity in adulthood,
Ke Wu +5 more
doaj +2 more sources
The Importance of Visceral Hypersensitivity in Irritable Bowel Syndrome-Plant Metabolites in IBS Treatment. [PDF]
Pharmaceuticals (Basel), 2023 The visceral stimuli from the digestive tract are transmitted via afferent nerves through the spinal cord to the brain, where they are felt as pain. The overreaction observed in the brain of irritable bowel syndrome (IBS) patients may be due to increased
Dudzińska E +4 more
europepmc +2 more sources
Enteric glia promote visceral hypersensitivity during inflammation through intercellular signaling with gut nociceptors. [PDF]
Sci Signal, 2023 Inflammation in the intestines causes abdominal pain that is challenging to manage. The terminals of sensory neurons innervating the gut are surrounded by glia. Here, using a mouse model of acute colitis, we found that enteric glia contribute to visceral
Morales-Soto W +3 more
europepmc +2 more sources
Long-lasting visceral hypersensitivity in a model of DSS-induced colitis in rats. [PDF]
Neurogastroenterol Motil, 2022 Persistent visceral hypersensitivity is a key component of functional and inflammatory gastrointestinal diseases. Current animal models fail to fully reproduce the characteristics of visceral pain in humans, particularly as it relates to persistent ...
López-Estévez S +3 more
europepmc +2 more sources
Spinal P2X4 Receptors Involved in Visceral Hypersensitivity of Neonatal Maternal Separation Rats. [PDF]
Purinergic Signal, 2023 Tang Y +8 more
europepmc +2 more sources
Acta Pharmacologica Sinica, 2021 Accumulating evidence shows that agents targeting gut dysbiosis are effective for improving symptoms of irritable bowel syndrome (IBS). However, the potential mechanisms remain unclear.
Jindong Zhang +13 more
semanticscholar +1 more source