Results 11 to 20 of about 18,784 (212)
Frontiers in Pharmacology, 2021 Visceral hypersensitivity as a common clinical manifestation of irritable bowel syndrome (IBS) may contribute to the development of chronic visceral pain.
Si-Ting Huang +6 more
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Frontiers in Neuroscience, 2022 Patients with irritable bowel syndrome (IBS) experience not only enhanced visceral pain but also emotional comorbidities, such as anxiety and depression. Early life stress (ELS) is a high-risk for the development of IBS.
Le Guan +10 more
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Gut pain & visceral hypersensitivity [PDF]
British Journal of Pain, 2013 Visceral pain is a highly complex entity whose experience is variable in health and disease. It can occur in patients with organic disease and also in those without any readily identifiable structural or biochemical abnormality such as in the functional gastrointestinal disorders (FGID).
Adam D, Farmer, Qasim, Aziz
openaire +2 more sources
Contemporary management of pain in cirrhosis: Toward precision therapy for pain
Hepatology, EarlyView., 2022 Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman +4 more
wiley +1 more source
The role of visceral hypersensitivity in the pathogenesis of irritable bowel syndrome
Терапевтический архив, 2021 This research includes visceral sensitivity and its mechanisms involved in the development of irritable bowel syndrome. Visceral hypersensitivity occupies the key place.
Alina A. Makarova +4 more
doaj +1 more source
Visceral hypersensitivity: facts, speculations, and challenges [PDF]
Gut, 2001 Visceral hypersensitivity is currently the holy grail....it is widely regarded as the reason for the development of functional gastrointestinal diseases, including functional dyspepsia and irritable bowel syndrome.1 Although the field has advanced considerably in the past decade, it is necessary to take stock and realistically appraise our current ...
M, Camilleri, B, Coulie, J F, Tack
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Adrenergic β2-receptors mediates visceral hypersensitivity induced by heterotypic intermittent stress in rats. [PDF]
PLoS ONE, 2014 Chronic visceral pain in patients with irritable bowel syndrome (IBS) has been difficult to treat effectively partially because its pathophysiology is not fully understood.
Chunhua Zhang +7 more
doaj +1 more source
Visceral hypersensitivity in irritable bowel syndrome [PDF]
Journal of Gastroenterology and Hepatology, 2011 AbstractAltered central processing, abnormal gastrointestinal motility and visceral hypersensitivity may be possible major pathophysiology of irritable bowel syndrome (IBS). These factors affect each other and are probably associated with development of IBS symptoms.It has been confirmed that lower pain threshold to colonic distention was observed in ...
Motoyori, Kanazawa +2 more
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NaV1.1 inhibition can reduce visceral hypersensitivity [PDF]
JCI Insight, 2018 Functional bowel disorder patients can suffer from chronic abdominal pain, likely due to visceral hypersensitivity to mechanical stimuli. As there is only a limited understanding of the basis of chronic visceral hypersensitivity (CVH), drug-based management strategies are ill defined, vary considerably, and include NSAIDs, opioids, and even ...
Juan Salvatierra +15 more
openaire +5 more sources
Frontiers in Microbiology, 2022 BackgroundIt is well-established that several features of modern lifestyles, such as shift work, jet lag, and using electronics at night, disturb normal circadian rhythm and increase the risk of suffering from functional gastrointestinal disease ...
Lilin Hu +5 more
doaj +1 more source