Results 21 to 30 of about 21,147 (220)
The Importance of Visceral Hypersensitivity in Irritable Bowel Syndrome—Plant Metabolites in IBS Treatment [PDF]
Pharmaceuticals, 2023 Ewa Dudzińska +2 more
exaly +2 more sources
Frontiers in Pharmacology, 2021 Visceral hypersensitivity is one of the pivotal pathophysiological features of visceral pain in irritable bowel syndrome (IBS). Small-conductance Ca2+-activated K+ channel (SK) is critical for a variety of functions in the central nervous system (CNS ...
Ning-Ning Ji +7 more
doaj +1 more source
Pathophysiology of stress-induced visceral hypersensitivity [PDF]
, 2014 Visceral hypersensitivity is observed in the majority of patients with IBS and considered a pathophysiological mechanism. The aim of the work described in this thesis was to obtain a better understanding of the stress-related pathophysiology of visceral hypersensitivity. Investigations were carried out in the rat model of maternal separation.
Stanisor, O.I.
core +6 more sources
Electroacupuncture at ST36 Alleviates Visceral Hypersensitivity and Anxiety via ACC-AIC Circuit Modulation in IBS Rats. [PDF]
Neuropsychiatr Dis TreatDan Wang,1 Yixuan Guo,2 Zhichun Wu,3 Haiyan Zhang4 1College of Traditional Chinese Medicine, Shandong University of Traditional Chinese Medicine, Jinan, Shandong, 250355, People’s Republic of China; 2College of Acupuncture-Moxibustion and Tuina, Shandong
Wang D, Guo Y, Wu Z, Zhang H.
europepmc +3 more sources
Effect of the 5-HT4 receptor and serotonin transporter on visceral hypersensitivity in rats [PDF]
Brazilian Journal of Medical and Biological Research, 2012 Visceral hypersensitivity plays an important role in motor and sensory abnormalities associated with irritable bowel syndrome, but the underlying mechanisms are not fully understood.
Chi Yan +4 more
doaj +3 more sources
Frontiers in Cellular Neuroscience, 2022 Irritable bowel syndrome (IBS) is a common gastrointestinal disorder characterized by recurrent visceral pain and altered bowel habits (diarrhea or constipation). However, the molecular and pathological mechanisms are poorly understood.
Yuan Liu +10 more
doaj +1 more source
Detection and Evaluation Methods of Visceral Sensitivity in Irritable Bowel Syndrome: a Review of the Latest Developments [PDF]
Zhongguo quanke yixue, 2023 Visceral hypersensitivity is one major pathophysiological characteristic of irritable bowel syndrome (IBS) , a common functional bowel disorder. The detection and evaluation of visceral hypersensitivity are of practical significance for the guidance of ...
HOU Yujun, ZHAO Ying, JIANG Huiling, TAN Yu, ZHANG Wei, LI Ying, ZHENG Qianhua
doaj +1 more source
Contemporary management of pain in cirrhosis: Toward precision therapy for pain
Hepatology, EarlyView., 2022 Abstract Chronic pain is highly prevalent in patients with cirrhosis and is associated with poor health‐related quality of life and poor functional status. However, there is limited guidance on appropriate pain management in this population, and pharmacologic treatment can be harmful, leading to adverse outcomes, such as gastrointestinal bleeding ...
Alexis Holman +4 more
wiley +1 more source
Gut pain & visceral hypersensitivity [PDF]
British Journal of Pain, 2013 Visceral pain is a highly complex entity whose experience is variable in health and disease. It can occur in patients with organic disease and also in those without any readily identifiable structural or biochemical abnormality such as in the functional gastrointestinal disorders (FGID).
Adam D, Farmer, Qasim, Aziz
openaire +2 more sources
Frontiers in Neuroscience, 2022 Patients with irritable bowel syndrome (IBS) experience not only enhanced visceral pain but also emotional comorbidities, such as anxiety and depression. Early life stress (ELS) is a high-risk for the development of IBS.
Le Guan +10 more
doaj +1 more source