Results 51 to 60 of about 309,484 (272)
Mechanisms contributing to visceral hypersensitivity : focus on splanchnic afferent nerve signalling [PDF]
, 2015 This is the peer reviewed version of the following article: Deiteren, A., De Man, J. G., Keating, C., Jiang, W., De Schepper, H. U., Pelckmans, P. A., Francque, S. M. and De Winter, B. Y.
de Man, Joris +7 more
core +1 more source
Neurotrophin signaling and visceral hypersensitivity [PDF]
Frontiers in Biology, 2014 Neurotrophin family are traditionally recognized for their nerve growth promoting function and are recently identified as crucial factors in regulating neuronal activity in the central and peripheral nervous systems. The family members including nerve growth factor (NGF), brain-derived neurotrophic factor (BDNF), and neurotrophin-3 (NT-3) are reported ...
openaire +2 more sources
Stress-related alterations of visceral sensation: animal models for irritable bowel syndrome study. [PDF]
, 2011 Stressors of different psychological, physical or immune origin play a critical role in the pathophysiology of irritable bowel syndrome participating in symptoms onset, clinical presentation as well as treatment outcome.
Larauche, Muriel +2 more
core +2 more sources
Frontiers in Cellular Neuroscience, 2022 Tandospirone, a third-generation of antianxiety agent with fewer side effects, has been widely used in the treatment of anxiety. Moreover, it is interesting that tandospirone has been found to relieve gastrointestinal symptoms in patients with refractory
Ting-Ting Zhan +9 more
doaj +1 more source
Contemporary views on inflammatory pain mechanisms: TRPing over innate and microglial pathways. [PDF]
, 2016 Tissue injury, whether by trauma, surgical intervention, metabolic dysfunction, ischemia, or infection, evokes a complex cellular response (inflammation) that is associated with painful hyperalgesic states.
Guan, Zhonghui +2 more
core +2 more sources
Aluminum Ingestion Promotes Colorectal Hypersensitivity in RodentsSummary
Cellular and Molecular Gastroenterology and Hepatology, 2019 Background & Aims: Irritable bowel syndrome (IBS) is a multifactorial disease arising from a complex interplay between genetic predisposition and environmental influences. To date, environmental triggers are not well known.
Nicolas Esquerre +9 more
doaj +1 more source
Am J Physiol Gastrointest Liver Physiol, 2023 Sex differences in visceral nociception have been reported in clinical and preclinical studies, but the potential differences in sensory neural encoding of the colorectum between males and females are not well understood. In this study, we systematically
Guo T +5 more
europepmc +2 more sources
Perioperative and anesthetic deaths: toxicological and medico legal aspects [PDF]
, 2019 Background: Anesthesia has become safer during decades, though there is still a preventable mortality; the complexity of medical and surgical interventions, increasingly older and sicker patients, has created a host of new hazards in anesthesiology.
Argo A. +5 more
core +1 more source
Bioengineered, 2021 The current study aimed to investigate the effects of sodium butyrate on the level of colonic protein IRAK1 (interleukin-1 receptor-associated kinase 1) in irritable bowel syndrome (IBS) models as well as revealing the relationship between IRAKI level ...
Yuqin He +7 more
semanticscholar +1 more source
Journal of Pharmacological Sciences, 2023 Visceral hypersensitivity and leaky gut, which are mediated via corticotropin-releasing factor (CRF) and Toll-like receptor 4 are key pathophysiology of irritable bowel syndrome (IBS). Metformin was reported to improve these gastrointestinal (GI) changes.
Tsukasa Nozu +4 more
doaj +1 more source