Results 51 to 60 of about 18,784 (212)

A Systematic Review and Meta‐Analysis of Cardiac Interoceptive Accuracy in Anorexia Nervosa

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Interoceptive impairments have been suggested as an etiological factor in anorexia nervosa (AN) but have not been consistently confirmed across interoceptive dimensions and bodily systems. This systematic review and meta‐analysis provides a focused investigation of cardiac interoceptive accuracy (IAcc) in AN.
Claire Gend, Laure Remy, Annika P. C. Lutz   +2 more
wiley   +1 more source

NMDA receptor subunit expression and PAR2 receptor activation in colospinal afferent neurons (CANs) during inflammation induced visceral hypersensitivity

Molecular Pain, 2009
Background Visceral hypersensitivity is a clinical observation made when diagnosing patients with functional bowel disorders. The cause of visceral hypersensitivity is unknown but is thought to be attributed to inflammation.
Caudle Robert M, Suckow Shelby K
doaj   +1 more source

Symptom cluster profiles in adolescents with inflammatory bowel disease: Cross‐sectional study using ImproveCareNow data

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Sleep disturbance, pain, anxiety, depression, and fatigue are prevalent in adolescents and young adults with inflammatory bowel disease (IBD). These symptoms often present in co‐occurring sets, known as symptom clusters. We aimed to identify distinct symptom clusters and factors associated with symptom profiles in adolescents with ...
Caeli Malloy, Kurt Kroenke, Patrick O. Monahan, Susan M. Rawl, Steven J. Steiner, Wendy R. Trueblood Miller, for the ImproveCareNow Pediatric IBD Learning Health System   +6 more
wiley   +1 more source

New insights into visceral hypersensitivity—clinical implications in IBS [PDF]

Nature Reviews Gastroenterology & Hepatology, 2011
A subset of patients with IBS have visceral hypersensitivity and/or somatic hypersensitivity. Visceral hypersensitivity might have use as a clinical marker of IBS and could account for symptoms of urgency for bowel movements, bloating and abdominal pain. The mechanisms that lead to chronic visceral hypersensitivity in patients who have IBS are unclear.
QiQi, Zhou, G Nicholas, Verne
openaire   +2 more sources

Prevalence of disorders of gut–brain‐interaction in pediatric patients with in‐remission inflammatory bowel disease: An Italian multicenter study

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Pediatric patients with in‐remission inflammatory bowel disease (IBD) often report persistent gastrointestinal symptoms, suggesting a potential overlap with disorders of gut–brain‐interaction (DGBIs). While DGBIs affect up to 40% of the general population, their prevalence in quiescent IBD children remains limited.
Giovanna Quatrale, Niccolo’ Chirico, Luigi Colecchia, Giuseppe Stella, Francesco Proli, Pietro Pisano, Erminia Romeo, Paola De Angelis, Licia Pensabene, Giovanni Marasco, Giovanni Di Nardo, Giovanni Barbara, Antonio Gasbarrini, Franco Scaldaferri, Valentina Giorgio   +14 more
wiley   +1 more source

Visceral pain: gut microbiota, a new hope?

Journal of Biomedical Science, 2018
Background Visceral pain is a complex and heterogeneous disorder, which can range from the mild discomfort of indigestion to the agonizing pain of renal colic. Regulation of visceral pain involves the spinal cord as well as higher order brain structures.
Matteo M Pusceddu, Melanie G Gareau
doaj   +1 more source

Negative allosteric modulation of the mGlu7 receptor reduces visceral hypersensitivity in a stress-sensitive rat strain

Neurobiology of Stress, 2015
Glutamate, the main excitatory neurotransmitter in the central nervous system, exerts its effect through ionotropic and metabotropic receptors.
Rachel D. Moloney, Anna V. Golubeva, Richard M. O'Connor, Mikhail Kalinichev, Timothy G. Dinan, John F. Cryan   +5 more
doaj   +1 more source

Regional brain activation during rectal distention and attenuation with alosetron in a nonhuman primate model of irritable bowel syndrome

FASEB BioAdvances, 2022
Greater understanding of the mechanism that mediates visceral pain and hypersensitivity associated with irritable bowel syndrome (IBS) would facilitate the development of effective therapeutics to manage these symptoms.
Rintaro Fujii, Yuji Awaga, Kenya Nozawa, Mayumi Matsushita, Aldric Hama, Takahiro Natsume, Hiroyuki Takamatsu   +6 more
doaj   +1 more source

Focused Ultrasound for the Treatment of Circuit and Molecular Pathology in Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Focused ultrasound is rapidly emerging as a novel technology for the development of symptomatic therapies and supporting disease‐modifying treatments for Parkinson's disease (PD). At the forefront of this development is thermoablation using high‐intensity focused ultrasound, an incisionless treatment that has been extensively tested in ...
Rikke Hahn Kofoed, Victor Schwartz Hvingelby, Jose A. Pineda‐Pardo, Javier Blesa, Steffen Paschen, Anurag Tandon, Juho Joutsa, Andreas Nørgaard Glud   +7 more
wiley   +1 more source

Cytokines in the colon, central nervous system and serum of irritable bowel syndrome rats

European Journal of Medical Research, 2021
Objective The aim of this study was to detect the expression of interleukin (IL)-1β and transforming growth factor (TGF)-β1 in the colonic tissue and serum of irritable bowel syndrome (IBS) rats, as well as the distribution and expression of ...
Guanqun Chao, Zhaojun Wang, Xinli Chen, Shuo Zhang   +3 more
doaj   +1 more source