Results 81 to 90 of about 309,484 (272)

The use of drug calendars for the diagnosis of cutaneous drug eruptions in the age of electronic medical records [PDF]

open access: yes, 2020
A morbilliform drug eruption is the most common condition leading to a dermatology consultation for a patient in the hospital. Timing is an important diagnostic tool since the onset of a skin rash usually takes place within days-to-weeks of the start of ...
Cohen, Philip R, Grossman, Marc E
core  

Symptom cluster profiles in adolescents with inflammatory bowel disease: Cross‐sectional study using ImproveCareNow data

open access: yesJournal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Sleep disturbance, pain, anxiety, depression, and fatigue are prevalent in adolescents and young adults with inflammatory bowel disease (IBD). These symptoms often present in co‐occurring sets, known as symptom clusters. We aimed to identify distinct symptom clusters and factors associated with symptom profiles in adolescents with ...
Caeli Malloy   +6 more
wiley   +1 more source

Diet–microbial cross–talk underlying increased visceral perception

open access: yesGut Microbes, 2023
Visceral hypersensitivity, a fundamental mechanism of chronic visceral pain disorders, can result from both central or peripheral factors, or their combination. As an important regulator of normal gut function, the gut microbiota has been implicated as a
Giada De Palma   +2 more
doaj   +1 more source

Functional bowel disease : a challenging frontier in gastroenterology [PDF]

open access: yes, 1999
The last 30 years have seen incredible advances in the science and practice of gastroenterology and hepatology. In the 1970s, the fiberoptic endoscopic revolution facilitated the visualization of the mucosa of a large segment of the gastrointestinal ...
Camilleri, Michael
core  

Blockade of BDNF signalling attenuates chronic visceral hypersensitivity in an IBS‐like rat model

open access: yesEuropean Journal of Pain, 2020
Irritable bowel syndrome (IBS) is a common functional disease characterized by chronic abdominal pain and changes in bowel movements. Effective therapy for visceral hypersensitivity in IBS patients remains challenging.
F. Fan   +7 more
semanticscholar   +1 more source

Fundamentals of neurogastroenterology: Basic science [PDF]

open access: yes, 2016
This review examines the fundamentals of neurogastroenterology that may underlie the pathophysiology of functional GI disorders (FGIDs). It was prepared by an invited committee of international experts and represents an abbreviated version of their ...
Artis   +52 more
core   +1 more source

Bifidobacterium longum alleviates irritable bowel syndrome-related visceral hypersensitivity and microbiota dysbiosis via Paneth cell regulation

open access: yesGut microbes, 2020
Although the oral administration of Bifidobacterium longum (B. longum) relieves the signs of irritable bowel syndrome (IBS) in clinical settings, the mechanisms underlying its effects are unclear.
Chunhua Zhou   +11 more
semanticscholar   +1 more source

Focused Ultrasound for the Treatment of Circuit and Molecular Pathology in Parkinson's Disease

open access: yesMovement Disorders, EarlyView.
Abstract Focused ultrasound is rapidly emerging as a novel technology for the development of symptomatic therapies and supporting disease‐modifying treatments for Parkinson's disease (PD). At the forefront of this development is thermoablation using high‐intensity focused ultrasound, an incisionless treatment that has been extensively tested in ...
Rikke Hahn Kofoed   +7 more
wiley   +1 more source

Pronociceptive changes in response properties of rostroventromedial medullary neurons in a rat model of peripheral neuropathy [PDF]

open access: yes, 2007
The spared nerve injury (SNI) model of peripheral neuropathy produces a robust and long-lasting hypersensitivity. Previous behavioural studies suggest that brainstem–spinal pathways originating in or relaying through the rostroventromedial medulla (RVM)
Almeida, Armando   +2 more
core   +1 more source

Histamine antagonism and postinflammatory visceral hypersensitivity

open access: yesGut, 2014
Abdominal pain is one of the most difficult to treat symptoms in patients suffering from IBS. Recent evidence shows that abnormal perception of visceral stimuli, or visceral hypersensitivity, represents an important underlying mechanism. Of interest, similar mechanisms may be involved in abdominal pain reported by UC and Crohn's disease patients in ...
openaire   +3 more sources

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