Results 81 to 90 of about 18,784 (212)

Exploring Associations of Different Types of Childhood Trauma With Symptomatology in Irritable Bowel Syndrome

Neurogastroenterology &Motility, EarlyView.
The current cross‐sectional study aimed to elucidate the impact of different types of childhood trauma on IBS symptomatology. Our findings strongly support the significant role of childhood trauma in IBS pathology and indicate the specific relevance of emotional abuse influencing not only gastrointestinal symptoms but also extraintestinal and ...
Tetyana Bureychak, Jenny Sjödahl, Nawroz Barazanji, Gustav Orell, Olivia Book, Rozalyn Simon, Olga Bednarska, Adriane Icenhour, Susanna Walter   +8 more
wiley   +1 more source

Intestinal metabolite homocysteine participates in the regulation of irritable bowel syndrome [PDF]

Jichu yixue yu linchuang
Objective To investigate the role of homocysteine (Hcy) in the pathogenesis of irritable bowel syndrome (IBS) and its effects on intestinal motility, visceral hypersensitivity, and barrier function.
LU Shaochong, YE Haozhen, HOU Songyuan, ZHOU Yesheng, LIU Si, ZHU Shengtao
doaj   +1 more source

Antinociceptive effect of berberine on visceral hypersensitivity in rats

World Journal of Gastroenterology, 2013
To assess the protective effect of berberine administration and the role of nitric oxide (NO) in visceral hypersensitivity.Fifty male Sprague-Dawley rats were randomly assigned to five groups. An inflammatory bowel disease model was induced in rats by intracolonic instillation of 1 mL 4% acetic acid at 8 cm proximal to the anus for 30 s and restraint ...
Tang, Qing-Lin, Lai, Min-Ling, Zhong, Yuan-Fu, Wang, Ai-Min, Su, Jun-Kai, Zhang, Ming-Qing   +5 more
openaire   +3 more sources

Beyond Malabsorption: The Need for Symptom‐Based Assessment in Suspected Lactose Intolerance. Lessons From a Test‐Specific Symptom Assessment

Neurogastroenterology &Motility, EarlyView.
Breath test–proven malabsorption does not reliably predict symptoms. Many patients without malabsorption still develop significant symptoms. Symptoms after lactose ingestion are linked to fructose sensitivity and functional GI disorders. Validated, test‐specific symptom assessment is required to identify patients who may benefit from treatment ...
Johann Hammer, Heinz F. Hammer
wiley   +1 more source

Effects of Electroacupuncture at ST36 on Visceral Pain and Inflammatory Markers in IBS Rats

Neurogastroenterology &Motility, EarlyView.
Electroacupuncture (EA) at ST36 significantly reduced visceral pain and colonic inflammation in IBS model rats. EA increased pain thresholds, lowered AWR scores, and downregulated key inflammatory mediators (IL‐1β, IL‐6, TNF‐α, TRPV1, NF‐κB). These findings highlight ST36‐targeted EA as a promising therapeutic strategy for IBS visceral hypersensitivity
Ya‐bo Hao, Yan‐lin Liu, Xiao‐mei Wang, Kai Cheng, Qing‐yu Tu, Fei Dai, Xi‐bing Yang   +6 more
wiley   +1 more source

Effect of Linaclotide on Colonic Motility Assessed With Intraluminal Colonic High‐Resolution Manometry in Healthy Subjects. An Acute, Open Label, Randomized, Crossover, Reader‐Blinded Study

Neurogastroenterology &Motility, EarlyView.
Our study showed that, in healthy controls, acute administration of linaclotide increased the total number of long‐distance propagating and the pre‐prandial pancolonic pressurizations. Further studies need to address whether the observed effects are directly or indirectly mediated by the mechanism of action of this useful medication to treat chronic ...
Christian Lambiase, Giuseppe Pagliaro, Silvia Cocca, Eveline Deloose, Ingrid Demedts, Riccardo Morganti, Jan Tack, Maura Corsetti   +7 more
wiley   +1 more source

Brain functional connectivity is associated with visceral sensitivity in women with Irritable Bowel Syndrome

NeuroImage: Clinical, 2017
Increased perception of visceral stimuli is a key feature of Irritable Bowel Syndrome (IBS). While altered resting-state functional connectivity (rsFC) has been also reported in IBS, the relationship between visceral hypersensitivity and aberrant rsFC is
Adriane Icenhour, Suzanne T. Witt, Sigrid Elsenbruch, Mats Lowén, Maria Engström, Kirsten Tillisch, Emeran A. Mayer, Susanna Walter   +7 more
doaj   +1 more source

Haplotype‐Resolved Genome Assembly and Population Genomics Reveal Evolutionary History and Agronomic Traits of Mulberry

Plant Biotechnology Journal, EarlyView.
ABSTRACT Mulberry is a representative economic tree species valued for both poverty alleviation and medicinal use. To advance the understanding of mulberry genomics and demography, we assembled high‐quality haploid genomes of two widely cultivated mulberry varieties NS14 and QS1, and analysed 376 accessions from 12 countries, including 39 ancient trees
Zhifeng Wang, Peigang Liu, Chengzhi Jiao, Yazhou Zhang, Zilong Xu, Tianbao Lin, Yan Zhu, Xin Jing, Yuan Huang, Nan Chao, Mengjie Zhao, Yan Liu, Huizi Liu, Bo Sun, Fen Zhang, Quanzi Li, Zhiqiang Lv, Xuepeng Sun, Ying‐Chung Jimmy Lin, Jia Wei   +19 more
wiley   +1 more source

Dissecting the Cell‐Type‐Specific Response to an Emerging Tobamovirus in Tomato Reveals Cultivar‐Dependent Involvement of Brassinosteroid Signalling

Plant Biotechnology Journal, EarlyView.
ABSTRACT Plant viruses drive widespread crop epidemics, yet the host plant responses across different cell types, particularly how these responses are influenced by cultivars with varying genetic backgrounds, including the presence of resistance (R) genes, remain poorly understood. Using tomato brown rugose fruit virus (ToBRFV) and two tomato cultivars,
Yuhong Zhang, Shan Bu, Yuxin Nie, Luyou Wang, Jiayi Liu, Junchen Xu, Jiejun Peng, Fei Yan, Jian Wu   +8 more
wiley   +1 more source

Living in the Mycelial World

Topics in Cognitive Science, EarlyView.
Abstract This manuscript documents a systematic ethnomycological analysis of ethnographic archives. Focusing on texts describing human–fungi interactions, I conduct a global, cross‐cultural review of mushroom use, covering 193 societies worldwide. The study reveals diverse mushroom‐related cultural practices, emphasizing the significance of fungi ...
Roope O. Kaaronen
wiley   +1 more source