Results 91 to 100 of about 119,689 (246)

Effect of Serum Vitamin B12 Levels on Brain Volumes

Current Research in MRI
Objective: To research the relationship between brain volumes and serum vitamin B12 markers. Methods: To investigate the volume changes of serum vitamin B12 markers in brain magnetic resonance imaging measurements of 62 participants admitted to the
Hatice Cakir, Mukadder Sunar, Ozlem Celik Aydin, Osman Kagan Cakir   +3 more
doaj   +1 more source

Thiocarbamoylimidates as Precursors of New 5‐Amino‐1,2,4‐Triazole and Oxadiazole Derivatives In Silico Prediction of Absorption, Distribution, Metabolism, and Excretion Parameters

ChemPlusChem, EarlyView.
1,2,4‐triazole and oxadiazole motifs are synthesized from thiocarbamoylimidates precursors, under mild conditions (40 °C) in the environmentally friendly water/ethanol reaction medium. The reaction is highly versatile and allows for the introduction of a wide variety of functional groups.
Oumaima Gatri, Thierry Roisnel, Marie Cordier, Vincent Dorcet, Mohamed Lotfi Efrit, Cédric Fischmeister   +5 more
wiley   +1 more source

Multivariate modular metabolic engineering and medium optimization for vitamin B12 production by Escherichia coli

Synthetic and Systems Biotechnology
Vitamin B12 is a complex compound synthesized by microorganisms. The industrial production of vitamin B12 relies on specific microbial fermentation processes. E.
Feitao Chen, Huan Fang, Jianghua Zhao, Pingtao Jiang, Huina Dong, Ying Zhao, Huiying Wang, Tongcun Zhang, Dawei Zhang   +8 more
doaj   +1 more source

Exploring a causal role of DNA methylation in the relationship between maternal vitamin B12 during pregnancy and child’s IQ at age 8, cognitive performance and educational attainment:a two-step Mendelian randomization study [PDF]

, 2017
An adequate intake of vitamin B12 during pregnancy plays an important role in offspring neurodevelopment, potentially via epigenetic processes. We used a two-step Mendelian randomization approach to assess whether DNA methylation plays a mediating and ...
Berryman, Katie, Caramaschi, Doretta, Davey Smith, George, Lewis, Sarah, Nohr, Ellen, Relton, Caroline, Sharp, Gemma   +6 more
core   +2 more sources

The Prevalence and Implications of Polypharmacy in Individuals With Type 1 Diabetes

Clinical Pharmacology &Therapeutics, EarlyView.
Polypharmacy is increasingly recognized as a relevant issue in diabetes care, but its prevalence and clinical relevance in individuals with type 1 diabetes remain underexplored. This study aimed to determine the prevalence of polypharmacy and to identify associated clinical and psychological factors. Participants were recruited from a tertiary diabetes
Namam Ali, Stephan van Erp, Cornelis Kramers, Cornelis J. Tack, Bastiaan E. de Galan   +4 more
wiley   +1 more source

Association of maternal and cord vitamin B12 levels with anthropometry in term neonates born to malnourished mothers in coastal South India [version 2; peer review: 2 approved]

F1000Research
Background Malnourished pregnant women are at increased risk of micronutrient deficiency. We assessed the vitamin B12 status in both malnourished and normally nourished pregnant women and their neonates.
Poornima Manjrekar, Suchetha Rao, Sugapradha GR, Ramesh Holla   +3 more
doaj   +1 more source

Blood Concentrations of Homocysteine and Methylmalonic Acid among Demented and Non-Demented Swedish Elderly with and without Home Care Services and Vitamin B12 Prescriptions

Dementia and Geriatric Cognitive Disorders Extra, 2012
Background and Aims: Total plasma homocysteine (tHcy) has been suggested as a risk factor of dementia. Our aim was to investigate potential differences in tHcy status in relation to the prescription of vitamin B12 and dementia diagnosis.
Nils-Olof Hagnelius, Lars-Olof Wahlund, Jörn Schneede, Torbjörn K. Nilsson   +3 more
doaj   +1 more source

Assessing Severity in Anorexia Nervosa Using Alternative Criteria to the DSM‐5 in a Cross‐Sectional Study

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective This study compared overvaluation of weight and shape (OWS), drive for thinness (DT), and their combination (OWS‐DT) as alternative severity classifications for anorexia nervosa (AN) to the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM‐5) severity classification.
Esther Henriet, Joanna Norton, Maude Seneque, Laurent Maimoun, Philippe Courtet, Sébastien Guillaume   +5 more
wiley   +1 more source

High-folate-low-vitamin B12 interaction syndrome

European Journal of Case Reports in Internal Medicine
Introduction: Vitamin B12 deficiency is characterised by haematological and neurological complications, from mild symptoms (e.g. fatigue and paraesthesia), to severe symptoms (e.g. pancytopenia and combined degeneration of the spinal cord).
Claudia Cicchini, Antonio De Magistris, Alberto Del Sasso, Donatella Livoli, Francesco Rocco Pugliese   +4 more
doaj   +1 more source

The Many Faces of Cobalamin (Vitamin B12) Deficiency

Mayo Clinic Proceedings: Innovations, Quality & Outcomes, 2019
Although cobalamin (vitamin B12) deficiency was described over a century ago, it is still difficult to establish the correct diagnosis and prescribe the right treatment.
Bruce H.R. Wolffenbuttel, MD, PhD, Hanneke J.C.M. Wouters, BSc, M. Rebecca Heiner-Fokkema, PhD, Melanie M. van der Klauw, MD, PhD   +3 more
doaj   +1 more source