Results 91 to 100 of about 773,516 (423)

PSMD14 Stabilizes SLC7A11 to Ameliorate Glucocorticoid‐Induced Osteoporosis by Suppressing Osteocyte Ferroptosis

open access: yesAdvanced Science, EarlyView.
Glucocorticoid‐induced osteoporosis (GIOP) triggers osteocyte ferroptosis via SLC7A11 degradation. PSMD14 stabilizes SLC7A11 by counteracting glucocorticoid‐driven ubiquitination, preserving cystine uptake and glutathione synthesis. AAV‐mediated PSMD14 delivery or its agonist Pantethine rescues osteocyte survival and bone loss in GIOP mice.
Yifeng Shi   +20 more
wiley   +1 more source

Vaccination rates modulate the correlation between country latitude and covid-19 surge date arising this autumn 2021 [PDF]

open access: yesarXiv, 2021
A clear linear correlation of covid-19 surge date with country latitude was observed last autumn 2020, but not with temperature, nor with humidity, pointing the seasonal vitamin D status decline as a contributor factor. Well vaccinated European countries are this autumn 2021 repeating explosive surges.
arxiv  

The prevalence of vitamin B12 deficiency in a random sample from the Australian population

open access: yes, 2014
 Objective: Vitamin B12 deficiency is common in older adults, and may increase the risk of cognitive impairment. The distribution of vitamin B12 insufficiency in younger age groups is less studied. This study aims to assess the prevalence of vitamin
Ames,D   +9 more
core   +1 more source

Shape‐Selective Molecular Separations Enabled by Rigid and Interconnected Confinements Engineered in Conjugated Microporous Polymer Membranes

open access: yesAdvanced Science, EarlyView.
Conjugated microporous polymer membranes with narrowly distributed network pores are prepared by diffusion‐modulated electropolymerization. This approach precisely controls the monomer diffusion and coupling processes, regulating the crosslinking degree to prevent broad aggregate pores and microporous defects.
Yanqiu Lu   +4 more
wiley   +1 more source

Microporous Polymer Membranes: Molecular Stents Enhanced Solvent‐Accessibility for Organic Solvent Transport

open access: yesAdvanced Science, EarlyView.
A novel microporous polyimide (PI‐TB‐NDI) is designed for enhanced organic solvent nanofiltration. By incorporating o‐methyl groups into the Tröger's base (TB) unit to create molecular stents, the polymer's intrinsic free volume is effectively increased without the need for post‐treatment.
Shuang Guo   +9 more
wiley   +1 more source

First principles investigations of electronic and magnetic properties of new rh.-B12N3 [PDF]

open access: yes, 2020
Considering rhombohedral alpha-boron, rh-B12 as a matrix hosting interstitials particularly triatomic linear ones as in B12C3 better known as B4C, the subnitride B12N3 is proposed herein. The N3 triatomic linear alignment labeled N2-N1-N2 resembles that found in the ionic sodium azide NaN3 characterized by a very short d(N1-N2)= 1.16 A.
arxiv   +1 more source

Folic Acid and Vitamin B12 Administration in CKD, Why Not?

open access: yesNutrients, 2019
Patients affected by chronic kidney disease (CKD) or end-stage renal disease (ESRD) experience a huge cardiovascular risk and cardiovascular events represent the leading causes of death.
I. Capelli   +6 more
semanticscholar   +1 more source

Effect of a Klamath algae product ("AFA-B12") on blood levels of vitamin B12 and homocysteine in vegan subjects: a pilot study [PDF]

open access: yes, 2009
none8Vitamin B12 is a critical nutrient that is often inadequate in a plant-based (vegan) diet, thus the inclusion of a reliable vitamin B12 source in a vegan diet is recommended as essential.
BENEDETTI, SERENA   +7 more
core   +1 more source

A Human Engineered Heart Tissue‐Derived Lipotoxic Diabetic Cardiomyopathy Model Revealed Early Benefits of Empagliflozin

open access: yesAdvanced Science, EarlyView.
This study develops a human engineered heart tissue‐derived model of diabetic cardiomyopathy that accurately replicates the dynamic changes in the structural, contractile, and electrophysiological properties of the myocardium. Furthermore, this model is used to confirm the direct protective effects of empagliflozin on the heart through an SGLT2 off ...
Lin Cai   +9 more
wiley   +1 more source

B12C2N Interstitial Boron subcarbonitride with peculiar magnetic properties: First principles investigations [PDF]

open access: yesarXiv, 2021
The subcarbides B12C3 and B13C2 known for their abrasive properties, can be structurally considered as carbon inserted rhombohedral alpha-B12 and expressed as B12{C-C-C} and B12(C-B-C). Using density functional theory DFT computations, the substitution of the central atom in the linear triatomic interstitials by N leads to an original new boron ...
arxiv  

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