Results 131 to 140 of about 797,518 (380)

Genetic Associations with Plasma B12, B6, and Folate Levels in an Ischemic Stroke Population from the Vitamin Intervention for Stroke Prevention (VISP) Trial [PDF]

, 2014
Background: B vitamins play an important role in homocysteine metabolism, with vitamin deficiencies resulting in increased levels of homocysteine and increased risk for stroke.
Al-Tahan, Aminoff, Aminoff, Donato, Fyfe, Grarup, Grasbeck, Hazra, Hazra, Hsu, Imerslund, Kamatani, Kirsch, Koury, Krintel, Kristiansen, Laurie, Lee, Li, Lin, Manichaikul, Matchar, McDowell, Nguyen, Ntaios, Owczarek-Lipska, Pennypacker, Pruim, Rajan, Reynolds, Selhub, Spence, Spinneker, Stabler, Stone, Stover, Tanaka, Tanner, Toole, Toole, Toprak, Van Den Bossche, Vardy, Wald, Wang, Wang, Webb, Yetley   +47 more
core   +2 more sources

Is high vitamin B12 status a cause of lung cancer?

International Journal of Cancer, 2019
Vitamin B supplementation can have side effects for human health, including cancer risk. We aimed to elucidate the role of vitamin B12 in lung cancer etiology via direct measurements of pre‐diagnostic circulating vitamin B12 concentrations in a nested ...
A. Fanidi, R. Carreras-Torres, Tricia L. Larose, Jian-Min Yuan, V. Stevens, S. Weinstein, D. Albanes, R. Prentice, M. Pettinger, Q. Cai, W. Blot, A. Arslan, A. Zeleniuch‐Jacquotte, M. McCullough, L. Le Marchand, L. Wilkens, C. Haiman, Xuehong Zhang, M. Stampfer, S. Smith-Warner, E. Giovannucci, G. Giles, A. Hodge, G. Severi, Mikael Johansson, K. Grankvist, A. Langhammer, B. Brumpton, Renwei Wang, Yu-Tang Gao, U. Ericson, S. Bojesen, S. Arnold, W. Koh, X. Shu, Y. Xiang, Hong-Lan Li, W. Zheng, Q. Lan, K. Visvanathan, Judith A. Hoffman-Bolton, P. Ueland, Ø. Midttun, N. Caporaso, M. Purdue, N. Freedman, J. Buring, I. Lee, H. Sesso, J. Michael Gaziano, J. Manjer, C. Relton, R. Hung, C. Amos, M. Johansson, P. Brennan   +55 more
semanticscholar   +1 more source

B12‐Cofactor Inactivation by Cobalt to Rhodium Mutation in Methylrhodibalamin: An Antivitamin B12 and Antibiotic

ChemistryEurope, EarlyView.
Replacement of cobalt in the organometallic B12‐cofactor methylcobalamin (MeCbl) by rhodium furnishes a structural mimic with a significantly stronger metal–carbon bond. This synthetically challenging formal metal‐mutation converts the naturally optimized biological methyl‐transfer catalyst MeCbl into a designed antivitamin B12, an inactivated B12 ...
Florian J. Widner, Klaus Wurst, Markus Ruetz, Christoph Kieninger, Christoph Kreutz, Michael D. Paxhia, Evelyne Deery, Martin J. Warren, Bernhard Kräutler   +8 more
wiley   +1 more source

Thiocarbamoylimidates as Precursors of New 5‐Amino‐1,2,4‐Triazole and Oxadiazole Derivatives In Silico Prediction of Absorption, Distribution, Metabolism, and Excretion Parameters

ChemPlusChem, EarlyView.
1,2,4‐triazole and oxadiazole motifs are synthesized from thiocarbamoylimidates precursors, under mild conditions (40 °C) in the environmentally friendly water/ethanol reaction medium. The reaction is highly versatile and allows for the introduction of a wide variety of functional groups.
Oumaima Gatri, Thierry Roisnel, Marie Cordier, Vincent Dorcet, Mohamed Lotfi Efrit, Cédric Fischmeister   +5 more
wiley   +1 more source

Déficit subclinique en vitamine B12 chez les nouveau-nés [PDF]

, 2014
Background: In the past years, we diagnosed subclinical vitamin B12 deficiency in infants with hypotonia, motor delay and/or infant malaise. These infants had elevated methylmalonic acid (MMA) in plasma and urine and plasma B12 in the low normal range ...
WILD, M.
core  

Association of maternal and cord vitamin B12 levels with anthropometry in term neonates born to malnourished mothers in coastal South India [version 2; peer review: 2 approved]

F1000Research
Background Malnourished pregnant women are at increased risk of micronutrient deficiency. We assessed the vitamin B12 status in both malnourished and normally nourished pregnant women and their neonates.
Poornima Manjrekar, Suchetha Rao, Sugapradha GR, Ramesh Holla   +3 more
doaj   +1 more source

Blood Concentrations of Homocysteine and Methylmalonic Acid among Demented and Non-Demented Swedish Elderly with and without Home Care Services and Vitamin B12 Prescriptions

Dementia and Geriatric Cognitive Disorders Extra, 2012
Background and Aims: Total plasma homocysteine (tHcy) has been suggested as a risk factor of dementia. Our aim was to investigate potential differences in tHcy status in relation to the prescription of vitamin B12 and dementia diagnosis.
Nils-Olof Hagnelius, Lars-Olof Wahlund, Jörn Schneede, Torbjörn K. Nilsson   +3 more
doaj   +1 more source

Assessing Severity in Anorexia Nervosa Using Alternative Criteria to the DSM‐5 in a Cross‐Sectional Study

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective This study compared overvaluation of weight and shape (OWS), drive for thinness (DT), and their combination (OWS‐DT) as alternative severity classifications for anorexia nervosa (AN) to the fifth edition of the Diagnostic and Statistical Manual of Mental Disorders (DSM‐5) severity classification.
Esther Henriet, Joanna Norton, Maude Seneque, Laurent Maimoun, Philippe Courtet, Sébastien Guillaume   +5 more
wiley   +1 more source

Vitamin B12 as a Treatment for Pain.

Pain Physician, 2019
BACKGROUND First isolated as cyanocobalamin in 1948, vitamin B12 has been explored for pain treatment almost since its discovery. With the advent of the opioid epidemic, safer treatments for pain are needed.
S. Buesing, M. Costa, Jan M. Schilling, T. Moeller‐Bertram   +3 more
semanticscholar   +1 more source