Results 21 to 30 of about 19,308 (251)

SIRT6 overexpression retards renal interstitial fibrosis through targeting HIPK2 in chronic kidney disease

Frontiers in Pharmacology, 2022
Introduction: Renal interstitial fibrosis is a common pathophysiological change in the chronic kidney disease (CKD). Nicotinamide adenine dinucleotide (NAD)-dependent deacetylase sirtuin 6 (SIRT6) is demonstrated to protect against kidney injury. Vitamin
Xiaoxue Li, Wenxin Li, Zhengzhipeng Zhang, Weidong Wang, Hui Huang   +4 more
doaj   +1 more source

Variable Selection in Untargeted Metabolomics and the Danger of Sparsity

Metabolites, 2020
The goal of metabolomics is to measure as many metabolites as possible in order to capture biomarkers that may indicate disease mechanisms. Variable selection in chemometric methods can be divided into the following two groups: (1) sparse methods that ...
Gerjen H. Tinnevelt, Udo F.H. Engelke, Ron A. Wevers, Stefanie Veenhuis, Michel A. Willemsen, Karlien L.M. Coene, Purva Kulkarni, Jeroen J. Jansen   +7 more
doaj   +1 more source

RELATIONSHIP BETWEEN GENDER, TRYPTOPHAN AND VITAMIN B3 CONSUMPTION PATTERNS WITH EMOTIONAL EATING IN OVERWEIGHT ADOLESCENTS

Media Gizi Indonesia, 2021
Emotional eating is the propensity to eat in response of negative emotions such as stress, anxiety and depression. Adolescents with overweight may experience an increase in leptin levels as well as disruption of serotonin resulting in disruption of ...
Kinanthi Dewi Mutiek, Mohammad Fanani, Adi Magna Patriadi Nuhriawangsa   +2 more
doaj   +1 more source

Niacin Enhancement for Parkinson’s Disease: An Effectiveness Trial

Frontiers in Aging Neuroscience, 2021
We previously reported that individuals with Parkinson’s disease (PD) present with lower vitamin B3 levels compared to controls. It may be related to carbidopa interaction, defective tryptophan metabolism, and stresses of night sleep disorder. Vitamin B3
Raymond Chong, Raymond Chong, Chandramohan Wakade, Chandramohan Wakade, Chandramohan Wakade, Chandramohan Wakade, Marissa Seamon, Marissa Seamon, Marissa Seamon, Banabihari Giri, Banabihari Giri, John Morgan, John Morgan, Sharad Purohit, Sharad Purohit   +14 more
doaj   +1 more source

Nature-inspired remodeling of (aza)indoles to meta-aminoaryl nicotinates for late-stage conjugation of vitamin B3 to (hetero)arylamines

Nature Communications, 2020
Vitamin B3 derivatives display a range of biological activities. Here, the authors report the synthesis of meta-aminoaryl nicotinates, derivatives of vitamin B3, and their late-stage conjugation with (hetero)arylamines, ultimately expanding the chemical ...
Begur Vasanthkumar Varun, Kannan Vaithegi, Sihyeong Yi, Seung Bum Park   +3 more
doaj   +1 more source

Insights into vitamin B3, B6 and C as inhibitor of steel reinforcement: A DFT + U study

, 2021
The adsorption behaviors of vitamin B3, B6 and C on γ-FeOOH surface are investigated by DFT + U approach. Vitamin B3 formed the most stable adsorption structure with the lowest adsorption energy.
Sun, Guoxing, Xiong, Chuansheng, Zhang, Yue, Xu, Qingqing, Sun, Ming, Wang, Pan, Hou, Dongshuai, Guan, Jing, Li, Mengmeng, Chen, Zheng, Ding, Zhiheng   +10 more
core   +1 more source

Vitamin B3 deficiency

, 2015
Vitamin B3, also referred to as niacin, is the generic term for nicotinic acid, its amide and their biologically active derivatives. These are essential in all cells for energy production, metabolism and DNA repair.
Labadarios, D., Parker, W., Steyn, N.P.
core   +3 more sources

The effect of in vitro simulated gastrointestinal digestive system on the biodegradation of B group vitamins in bread

Heliyon, 2022
Today, there is a growing interest in the consumption of whole grain products and the development of bread enriched with vitamins that have functional properties. Considerable losses arise in naturally found vitamins with food processing.
Jale Çatak, Merve Nur Gizlici
doaj   +1 more source

Synthesis of Mixed Dinucleotides by Mechanochemistry

Molecules, 2022
We report the synthesis of vitamin B1, B2, and B3 derived nucleotides and dinucleotides generated either through mechanochemical or solution phase chemistry.
Faisal Hayat, Mikhail V. Makarov, Luxene Belfleur, Marie E. Migaud   +3 more
doaj   +1 more source

Determination of niacin profiles in some animal and plant based foods by high performance liquid chromatography: association with healthy nutrition

Journal of Animal Science and Technology, 2019
Vitamin B3 (niacin) is essential for all living cells and plays a central role in energy metabolism and oxidative phosphorylation. Vitamin B3, a water-soluble vitamin, is present in the form of nicotinic
Jale Çatak
doaj   +1 more source