Results 61 to 70 of about 50,549 (249)

Relationship Between Diet and Tinnitus: Korea National Health and Nutrition Examination Survey [PDF]

Clinical and Experimental Otorhinolaryngology, 2018
Objectives This study aimed to analyze the association between nutritional intake and tinnitus prevalence by evaluating a large cross-sectional cohort.
Doh Young Lee, Young Ho Kim
doaj   +1 more source

Ideology and disease identity : the politics of rickets, 1929-1982 [PDF]

, 2013
How can we assess the reciprocal impacts of politics and medicine in the contemporary period? Using the example of rickets in twentieth century Britain, I will explore the ways in which a preventable, curable non-infectious disease came to have enormous ...
Apple, Arneil, Arneil, Benson, Berry, Bivins, British Paediatric Association, Carne, Chick, Dunnigan, Dunnigan, Dunnigan, Dunnigan, Ford, Ford, Ford, Ford, Frazer, Games, Grant, Heath, Hodgkin, Holmes, Hutt, Jameson, Kamminga, Kamminga, Lester, M'Gonigle, MacNalty, Magee, Marrack, McIntosh, McKay, Murcott, Orwell, Roberta Bivins, Robertson, Schwarz, Smerdon, Smith, Stanbury, Stewart, Swan, Walker, Webster, Webster, Webster, Webster, Whistler, Young   +50 more
core   +1 more source

Nicotinamide and Pyridoxine Supplementation Enhances Muscle Stem Cell Activity and Muscle Regeneration in Humans: A Randomized Placebo‐Controlled Clinical Trial of High Force Eccentric Contraction Recovery in Healthy Young Men

Advanced Science, EarlyView.
In a randomized clinical trial, we test the potential of combined nicotinamide (NAM) and pyridoxine (PN) to improve muscle recovery through muscle stem cell (MuSC) activity. Daily oral NAM and PN supplementation after high intensity muscle contractions enhances MuSC activation and differentiation, and accelerates muscle regeneration, providing new ...
Grith Højfeldt, Joris Michaud, Ann Damgaard, Karoline Karlog, Eugenia Migliavacca, Sonia Karaz, Elham Pazirandeh‐Micol, Odd E. Johansen, Leonidas G. Karagounis, Bjørk W. Helge, William Hagemann, Michael Kjaer, Jerome N. Feige, Pascal Stuelsatz, Abigail L. Mackey   +14 more
wiley   +1 more source

Water-Soluble Vitamins (Riboflavin, Niacin, Pantothenic Acid) in Dogs with Chronic Liver Disease vs. Healthy Controls

Veterinary Sciences
Background: Water-soluble vitamin deficiencies are common in human chronic liver disease (CLD) due to impaired metabolic pathways. Vitamins B2 (riboflavin), B3 (niacin), and B5 (pantothenic acid) assume critical roles in hepatic and lipid metabolism and ...
Verena Habermaass, Aurora Cogozzo, Francesco Bartoli, Valentina Vitelli, Rebecca Dini, Veronica Marchetti   +5 more
doaj   +1 more source

Cars2‐Mediated Cysteine Catabolism Drives Brown Fat Development and Thermogenesis Through Persulfidating EBF2

Advanced Science, EarlyView.
We demonstrate that Cars2, a cysteine catabolic enzyme in mouse iBAT, is critical for cold tolerance and brown adipocyte differentiation. Through its CPERS activity, Cars2 produces CysSSH/H2S to induce EBF2 persulfidation, promoting its interaction with PPARγ and BRG1 to enhance thermogenic gene expression.
Xin Peng, Hongyong Song, Yin Long, Kaimin Wu, Yinkun Fu, Wenkai Zhou, Wenyan Li, Zhe Shi, Xu‐Yun Zhao   +8 more
wiley   +1 more source

The decline of 6‐thioguanine nucleotides is not linked to impaired efficacy or safety of thiopurines in pregnant women with inflammatory bowel disease

British Journal of Clinical Pharmacology, EarlyView.
Background Thiopurines are used to maintain remission in inflammatory bowel disease (IBD). These drugs are metabolized into 6‐thioguanine nucleotides (6‐TGN), associated with efficacy, and 6‐methylmercaptopurine ribonucleotides (6‐MMPR), associated with adverse drug reactions. Pregnancy has been linked to a shift in thiopurine metabolism, characterized
Dianne G. Bouwknegt, Paola Mian, Femke Groen, Denise van den Berg‐Zuiddam, Andrea E. van der Meulen, Femke Crouwel, Nanne K. de Boer, Debbie S. Deben, Dennis R. Wong, Luc J. J. Derijks, Gerard Dijkstra, Arno R. Bourgonje, C. Janneke van der Woude, Marijn C. Visschedijk   +13 more
wiley   +1 more source

The nutritional levels and status of vitamins among children in Henan, China

Frontiers in Nutrition
BackgroundVitamins are vital for children’s health, and deficiencies can cause disorders, compromising quality of life and survival. This study systematically assesses multivitamin levels, nutritional status, and associated factors in children from Henan,
Xiaojuan Li, Nan Chen, Lei Guo, Yusheng Luan, Zhipeng Jin, Junmei Yang, Tiewei Li   +6 more
doaj   +1 more source

Vitamins as potent cancer treatments through regulating the activity and expression of MMP‐2 and MMP‐9

Bulletin of the Korean Chemical Society, EarlyView.
Vitamins could regulate both MMP‐2 and MMP‐9 expression and activity through transcriptional and MAPK signaling pathway modulation. This study highlights the potential of vitamins as low‐toxicity therapeutic or adjunct agents for targeting MMP‐mediated cancer progression. Abstract Matrix metalloproteinases (MMP‐2 and MMP‐9) are key regulators of cancer
Yen Thi Nguyen, Eungchan Kim, Ha Vy Thi Vo, Song Ja Kim, Namdoo Kim, Hyuck Jin Lee   +5 more
wiley   +1 more source

Çiriş Otu'nda (Asphodelus aestivus L.) Suda Çözünen Bazı Bileşiklerin Araştırılması

Süleyman Demirel Üniversitesi Fen-Edebiyat Fakültesi Fen Dergisi, 2011
Özet: Bu çalışmada, yemeği yapılarak tüketilen Çiriş otu yada yabani pırasa (Asphodelus aestivus L.)'daki indirgenmiş glutatyon (GSH), yükseltgenmiş glutatyon (GSSG), C vitamini ile tiamin klorür (B1 vitamini), riboflavin (B2 vitamini), nikotinik asit ...
Fikret Karataş, İbrahim Bektaş, Ayşe Birişik, Zeynep Aydın, Ali Kurtul   +4 more
doaj  

Mitochondrial dysfunction in PBMC: a potential sensor for metabolic dysfunction-associated steatotic liver disease and therapeutic insight for NAD+-increasing strategies [PDF]

Exploration of Digestive Diseases
The epidemic of metabolic dysfunction-associated steatotic liver disease (MASLD) is increasingly growing worldwide. Thus, there is an urgent need for novel, non-invasive, and reliable biomarkers to replace liver biopsy for the diagnosis and prognosis of ...
Julia Niño-Narvión, Joana Rossell, Marina Idalia Rojo-López, Estefanía Moreira, Eder Mateus, Antonio José Ruiz-Alcaraz, Bruno Ramos-Molina, Elizabeth Martínez-Rojo, Laurent O. Martinez, Maria Galán, Josep Julve   +10 more
doaj   +1 more source