Results 41 to 50 of about 446,252 (268)

Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription

FEBS Open Bio, EarlyView.
In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang, Mingqiang Deng, Dongmei He, Diqin Lai, Dongjun Liu, Dengyong Zhu, Zhenhua Zhang, Peng Tang, Chuanman Zhou, Menghui Yin, Xichen Bao   +10 more
wiley   +1 more source

Distribution and Utilization of Vitamin E in Different Organs of Wild Bats from Different Food Groups

Life
In this work, we examined the levels of vitamin E in the heart, liver, and kidneys of four species of adult male bats with distinct feeding habits. Our results indicate consistent vitamin E levels in the heart across all four bat species, suggesting the ...
Diego Antonio Mena Canata, Mara Silveira Benfato, Francielly Dias Pereira, María João Ramos Pereira, Pabulo Henrique Rampelotto   +4 more
doaj   +1 more source

Are α-tocopherol levels associated with improved glycaemia?

Journal of Nutrition & Intermediary Metabolism, 2019
Background/objective: Little Research has been done to evaluate the vitamin E status in healthy Singaporean adults, and to examine the associations between vitamin E status, adiposity, metabolic disorders, and bone health.
Xinyan Bi, Yi Ting Loo, Penny Liu Qing Yeo, Christiani Jeyakumar Henry   +3 more
doaj   +1 more source

Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model

FEBS Open Bio, EarlyView.
This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito, Haduki Asano, Ayano Ueki, Joe Sakamoto, Yasuhiro Kamei, Hayato Tokumoto, Ayaka Yazawa, Shigeki Kamitani   +7 more
wiley   +1 more source

Research Progress on the Enhancement of Immobilized Enzyme Catalytic Performance and Its Application in the Synthesis of Vitamin E Succinate

Molecules
Vitamin E succinate is a more mature vitamin E derivative, and its chemical stability and many effects have been improved compared with vitamin E, which can not only make up for the shortcomings of vitamin E application but also broaden the application ...
Liang Qu, Qiongya Lu, Liming Zhang, Fanzhuo Kong, Yuyang Zhang, Zhiyuan Lin, Xing Ni, Xue Zhang, Yani Zhao, Bin Zou   +9 more
doaj   +1 more source

The effect of polyphenols on the performance and antioxidant status of sows and piglets

Italian Journal of Animal Science, 2019
The aim of this study was to determine the efficacy of polyphenols in pigs. The experiment was performed on 52 sows divided into 4 groups. Untreated control sows (group 1) were not administered vitamin E in the premixes.
Krzysztof Lipiński, Zofia Antoszkiewicz, Magdalena Mazur-Kuśnirek, Daniel Korniewicz, Sylwia Kotlarczyk   +4 more
doaj   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Vitamin E levels in buccal cells of arsenicosis patients following vitamin E supplementation

Bangladesh Journal of Pharmacology, 2013
To understand the role of vitamin E in the treatment of arsenical melanosis and keratosis, the buccal cells of 19 patients, 14 arsenic exposed controls and 13 healthy volunteers were collected for the estimation of vitamin E both before and after ...
Mir Misbahuddin, Nadia Farha
doaj   +1 more source

Selenium and/or vitamin E upregulate the antioxidant gene expression and parameters in broilers

BMC Veterinary Research, 2022
Background In contrast to free radicals, the first line of protection is assumed to be vitamin E and selenium. The present protocol was designed to assess the roles of vitamin E and/or a selenium-rich diet that affected the blood iron and copper ...
Fatma Elgendey, Rasha A. Al Wakeel, Shabaan A. Hemeda, Aya Mohamed Elshwash, Sabreen E. Fadl, Aaser M. Abdelazim, Muhanad Alhujaily, Olla A. Khalifa   +7 more
doaj   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source