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A TTPA deletion is associated with retinopathy with vitamin E deficiency in the English Cocker Spaniel dog [PDF]

open access: goldG3 (Bethesda)
Retinopathy with vitamin E deficiency is a familial disease in the English Cocker Spaniel dog breed. Ophthalmic abnormalities observed in retinopathy with vitamin E deficiency-affected English Cocker Spaniel include lipofuscin granule deposition within ...
Oliver JAC   +4 more
core   +7 more sources

Chronic Vitamin E Deficiency Dysregulates Purine, Phospholipid, and Amino Acid Metabolism in Aging Zebrafish Skeletal Muscle [PDF]

open access: yesAntioxidants, 2023
Muscle wasting occurs with aging and may be a result of oxidative stress damage and potentially inadequate protection by lipophilic antioxidants, such as vitamin E.
Trent D. Henderson   +6 more
doaj   +2 more sources

The Association Between Vitamin E Deficiency and Critically Ill Children With Sepsis and Septic Shock [PDF]

open access: yesFrontiers in Nutrition, 2021
Background: Literature is scarce on the assessment of vitamin E status in septic children. We aim to investigate the prevalence of vitamin E deficiency in critically ill children with sepsis and septic shock and its association with clinical features and
Hongxing Dang   +11 more
doaj   +2 more sources

The low prevalence rate of vitamin E deficiency in urban adults of Wuhan from central China: findings from a single-center, cross-sectional study [PDF]

open access: yesEuropean Journal of Medical Research, 2023
Background Vitamin E is an essential nutrient in human body famous for its antioxidant and non-antioxidant functions. However, little is known about vitamin E deficiency status in urban adults of Wuhan from central China.
Ying Shen, Ke Liu, Xia Luo, Liming Cheng
doaj   +2 more sources

Cardiovascular and metabolic protection by vitamin e: A matter of treatment strategy? [PDF]

open access: yesAntioxidants, 2020
Cardiovascular diseases (CVD) cause about 1/3 of global deaths. Therefore, new strategies for the prevention and treatment of cardiovascular events are highly sought-after. Vitamin E is known for significant antioxidative and anti-inflammatory properties,
Lorkowski, Stefan   +3 more
core   +3 more sources

Potential of vitamin E deficiency, induced by inhibition of α-tocopherol efflux, in murine malaria infection [PDF]

open access: yesInt J Mol Sci, 2019
application/pdfAlthough epidemiological and experimental studies have suggested beneficial effects of vitamin E deficiency on malaria infection, it has not been clinically applicable for the treatment of malaria owing to the significant content of ...
255   +9 more
core   +2 more sources

Brain Vitamin E Deficiency During Development Is Associated With Increased Glutamate Levels and Anxiety in Adult Mice [PDF]

open access: yesFrontiers in Behavioral Neuroscience, 2018
Vitamin E, the most important lipophilic radical scavenging antioxidant in vivo, has a pivotal role in brain. In an earlier study, we observed that adult mice with a defect in the gene encoding plasma phospholipid transfer protein (PLTP) display a ...
Catherine M. Desrumaux   +25 more
doaj   +2 more sources

Ataxia with Vitamin E Deficiency

open access: yesPediatric Neurology Briefs, 1997
Vitamin E adminstration (100 U/kg daily) resulted in improvements in ataxia, motor strength, and mobility in 2 siblings of a consanguineous Bedouin family with Friedreich ataxia and low serum vitamin E levels treated at Soroka Medical Center, Beer Sheva, Israel.
J Gordon Millichap
openaire   +5 more sources

Vitamin D Deficiency and Exogenous Vitamin D Excess Similarly Increase Diffuse Atherosclerotic Calcification in Apolipoprotein E Knockout Mice [PDF]

open access: yesPLoS ONE, 2014
Background: Observational data associate lower levels of serum vitamin D with coronary artery calcification, cardiovascular events and mortality. However, there is little interventional evidence demonstrating that moderate vitamin D deficiency plays a ...
A Bas   +50 more
core   +5 more sources

Single-Cell RNA-seq Reveals Profound Alterations in Mechanosensitive Dorsal Root Ganglion Neurons with Vitamin E Deficiency. [PDF]

open access: yesiScience, 2019
Ninety percent of Americans consume less than the estimated average requirements of dietary vitamin E (vitE). Severe vitE deficiency due to genetic mutations in the tocopherol transfer protein (TTPA) in humans results in ataxia with vitE deficiency (AVED)
Bordbari, Matthew H   +9 more
core   +2 more sources

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