Results 51 to 60 of about 8,906,109 (167)

Sepsis in Dogs and Cats—Consensus Definition and Clinical Criteria

Journal of Veterinary Emergency and Critical Care, Volume 36, Issue 4, Page 445-469, July/August 2026.
ABSTRACT Sepsis is the clinical syndrome that results from the host response to severe or widespread infection and is a frequent cause of death in veterinary critical care settings. Rapid diagnosis aids early treatment initiation, and hence, how sepsis is defined and identified clinically has implications for patient outcomes.
Robert Goggs, Stefano Cortellini, Amy E. DeClue, Massimo Giunti, Kate Hopper, Julie M. Menard, Rodrigo C. Rabelo, Elizabeth A. Rozanski, Claire R. Sharp, Deborah C. Silverstein, Virginia Sinnott‐Stutzman, Giacomo Stanzani, John Bourgeois, Erik Fausak   +13 more
wiley   +1 more source

Properties of epoxide hydrolase from the yeast Rhodotorula glutinis [PDF]

, 2002
Epoxide hydrolases are ubiquitous enzymes that can be found in nearly all living organisms. Some of the enzymes play an important role in detoxifying xenobiotic and metabolic compounds.
Ariës-Kronenburg, N.A.E.
core  

Vascular Calcification: Mechanisms, Models, and Therapies

iNew Medicine, Volume 2, Issue 2, June 2026.
ABSTRACT Vascular calcification represents an active multifactorial process that mirrors several key features of skeletal bone mineralization. Clinically, it is characterized by diminished arterial compliance and increased arterial wall stiffness, both of which serve as independent predictors of significant adverse cardiovascular events.
Wenya Zhu, Shu Yang, Ziyi Chen, Xiaoxiao Yang, Zhen Liang, Yuanli Chen   +5 more
wiley   +1 more source

Challenging Anticoagulation With Warfarin and Heparin Following Mechanical Mitral Valve Replacement in a Patient With Infective Endocarditis: A Case Report Highlighting Diagnostic Difficulties

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT Warfarin remains the cornerstone of anticoagulation therapy following mechanical heart valve replacement. However, challenging anticoagulation responses, resistance to warfarin, and even more rarely to both warfarin and heparin pose significant clinical challenges and complicate management strategies.
Musawer Khan, Ayesha Ahmad, Moin Khan, F. N. U. Zainullah, Nauman Khan, Fatima Nazir, Wakil Ahmed, Naqeeb Ullah, Muhammad Anees, Kamil Ahmad Kamil   +9 more
wiley   +1 more source

Characterization and purification of the vitamin K-1 2,3 epoxide reductase system from rat liver

, 2001
The enzyme vitamin K-1 2,3 epoxide reductase is responsible for converting vitamin K-1 2,3 epoxide to vitamin K-1 quinone thus completing the vitamin K cycle.
Hutt, A J, Pallister, C J, Begent, L A, Cowell, D C, Steventon, G B, Hill, A P   +5 more
core   +1 more source

Evaluation of warfarin resistance using transcription activator-like effector nucleases-mediated vitamin K epoxide reductase knockout HEK293 cells [PDF]

, 2013
Single nucleotide polymorphisms in the vitamin K epoxide reductase (VKOR) gene have been successfully used for warfarin dosage prediction. However, warfarin resistance studies of naturally occurring VKOR mutants do not correlate with their clinical ...
Jin, D. Y., Tie, K., Tie, J. K., Stafford, D. W.   +3 more
core   +1 more source

Gap Analysis of Metabolic Conversions of Off‐Flavors and Antinutrients in Plant‐Based Substrates

Comprehensive Reviews in Food Science and Food Safety, Volume 25, Issue 3, May 2026.
ABSTRACT To drastically reduce the carbon footprint of the food production chain, a major shift towards alternatives to conventional meat and dairy products is required. The use of plant‐based proteins is a promising route, but it also comes with challenges: Plant‐based proteins often contain antinutritional factors and off‐flavors, which can ...
Robin I. Kuijpers, Isabel O. de Moya Clark, Tomás Cavaco, Vivian Nemanič, Beatrice Tagliabue, Ainhoa Valero‐Abad, Wiebe M. Wennekers, Mengqiu Zhang, Koen Van Zwet, Sanne Abeln, Sofia Moco, Caroline E. Paul, Halima Mouhib, Richard A. Notebaart, Eddy J. Smid, Bas Teusink, Herwig Bachmann   +16 more
wiley   +1 more source

Intravenous Administration of Vitamin K1 in Dogs and Cats Presented for Anticoagulant Rodenticide Poisoning: A Retrospective Study of 58 Cases

Journal of Veterinary Emergency and Critical Care, Volume 36, Issue 3, Page 365-371, May/June 2026.
ABSTRACT Objective To evaluate the safety of IV lecithin‐solubilizing agent‐based vitamin K1 (VK‐LSE) administration and compare the outcomes in dogs and cats with anticoagulant rodenticide (AR) poisoning that received IV VK‐LSE with or without exogenous coagulation factors (CF). Design Retrospective study (January 2010 to January 2022).
Camille Dartencet, Céline Pouzot‐Nevoret, Marine Poupon, Mark W. Kim, Bernard Allaouchiche, Alexandra Nectoux   +5 more
wiley   +1 more source

Ferroptotic neurodegeneration and diet: a narrative review

Alzheimer's &Dementia, Volume 22, Issue 4, April 2026.
Dietary regimes and separate components have been reported to reduce ferroptosis by (1) altering iron metabolism, (2) increasing antioxidant defense, and (3) reducing lipid peroxidation. This ultimately leads to reduced ferroptosis and neurodegeneration.
Ximaine R. van der Burg, Danielle V. Toen, Scott Ayton, Hanno Pijl, Louise van der Weerd   +4 more
wiley   +1 more source

Vitamin K and equine osteocalcin: an enigma explored

, 2020
Vitamin K has received considerably less attention over the past 50 years compared to other fat soluble vitamins. Intakes of vitamin K beyond that required for normal blood coagulation were believed to confer no additional benefits, and therefore rarely ...
Skinner, Jazmine Elizabeth
core   +1 more source