Results 71 to 80 of about 208,965 (228)
Advanced Science, EarlyView.Combined high‐glucose and hypoxic stress switches microglia into a TSPAN4‐dependent migrasome‐producing state. These migrasomes deliver pro‐angiogenic signals to endothelial cells, activating HIF‐1α/VEGF signaling, disrupting vascular junctions, and fueling pathological neovascularization. This work uncovers migrasome‐mediated immune‐vascular crosstalk
Jingyi Xu +12 more
wiley +1 more source
Advanced Science, EarlyView.A blue‐light‐crosslinked bilayer hydrogel was developed for local optic nerve repair. The adhesive GM‐Odex outer layer seals and anchors the lesion, while the non‐adhesive GM‐imid inner layer releases MPDA‐Cle without obstructing CSF flow. This system modulates oxidative and inflammatory microenvironments, supports oligodendrocyte differentiation and ...
Tonghe Pan +13 more
wiley +1 more source
GelsPurpose: To develop and preliminarily evaluate a hyaluronic acid–1,4-butanediol diglycidyl ether (HA-BDDE)/polyethylene glycol–tyramine (PEG-Tyramine) dual-hydrogel designed as a transparent and injectable vitreous substitute with suitable optical ...
Soheil Sojdeh +7 more
doaj +1 more source
A Hydrogel Vitreous Substitute that Releases Antioxidant
Macromolecular Bioscience, 2019 AbstractCurrent experimental vitreous substitutes only replace the physical functions of the natural vitreous humor. Removal of the native vitreous disrupts oxygen homeostasis in the eye, causing oxidative damage to the lens that likely results in cataract formation.
Nguyen K. Tram +5 more
openaire +3 more sources
Advanced Science, EarlyView.Field‐driven active colloids are framed as distributed micromachines in which externally supplied power, sensing, and control regulate task‐relevant states. By closing the loop between particle behavior, imaging, computation, and electric or magnetic actuation, these systems can progress from programmable motion toward adaptive functional outcomes ...
Ruchi Patel, Bhuvnesh Bharti
wiley +1 more source
Advanced Science, EarlyView.Intravitreal AAV2‐mediated AKAP1 restoration enhances mitochondrial fusion and biogenesis, improves bioenergetic capacity, and preserves mitochondrial integrity in glaucomatous RGCs. AKAP1 stabilizes presynaptic structure, maintaining synaptic protein expression, and limiting complement‐associated neuroinflammation.
Tonking Bastola +10 more
wiley +1 more source
BMC ChemistryThis study reports a facile and efficient synthesis of polymethylhydrosiloxane (PMHS) via a simplified hydrolysis–condensation of dichloromethylsilane (DCMS), eliminating the need for a separate multistep condensation stage. PMHS samples were prepared by
Mutiara Septiani +7 more
doaj +1 more source
Advanced Intelligent Discovery, EarlyView.AI‐based tools enable rapid characterization of bacterial ultrastructure in low‐dose cryogenic transmission electron microscopy. The envelope thickness tool quantifies membrane thickness and anisotropy. The flagella module analyzes filament morphology and detects cell‐flagella contacts.
Sita Sirisha Madugula +10 more
wiley +1 more source
Generation and Evaluation of Modified Opaque-2 Popcorn Suggests a Route to Quality Protein Popcorn
Frontiers in Plant Science, 2018 Introducing traits from dent corn to popcorn is challenging because it is difficult to recover adequate popping characteristics. QPM (Quality Protein Maize) is a dent corn variety carrying the opaque-2 (o2) mutation, specifying increased amounts of ...
Ying Ren +8 more
doaj +1 more source
, 2017 The transparent vitreous, which fills the posterior cavity of the eye, is incredibly engineered. The charged polyelectrolyte hyaluronic acid (HA) network swells to maintain the pressure in the eye, while stiff collagen type II bundles help absorb any ...
Morozova, Svetlana
core +1 more source