Results 101 to 110 of about 66,180 (284)

Oxidized type IV hypertriglyceridemic VLDL-remnants cause greater macrophage cholesteryl ester accumulation than oxidized LDL

Journal of Lipid Research, 1998
We have previously shown that very low density lipoproteins (VLDL, Sf 60–400) from subjects with type IV hyperlipoproteinemia (HTG-VLDL) will induce appreciable cholesteryl ester accumulation in cultured macrophages (J774A.1).
Stewart C. Whitman, Cynthia G. Sawyez, David B. Miller, Bernard M. Wolfe, Murray W. Huff   +4 more
doaj  

Die Differenzierung von VLDL-Subfraktionen in der Diagnostik von Typ III Hyperlipoproteinämien [PDF]

, 1977
K. H. Vogelberg
openalex   +1 more source

Bridging the gap in obesity research: A consensus statement from the European Society for Clinical Investigation

European Journal of Clinical Investigation, EarlyView.
This consensus highlights critical research gaps in obesity epidemiology, phenotypic heterogeneity and clinical management, calling for advanced methodologies, collaborative strategies and innovative policies to mitigate the global obesity epidemic and its socio‐economic impacts.
Federico Carbone, Jean‐Pierre Després, John P. A. Ioannidis, Ian J. Neeland, Gabriella Garruti, Luca Busetto, Luca Liberale, Stefano Ministrini, Gemma Vilahur, Thomas H. Schindler, Maria Paula Macedo, Agostino Di Ciaula, Marcin Krawczyk, Andreas Geier, Gyorgy Baffy, Maria Felicia Faienza, Ilaria Farella, Nicola Santoro, Gema Frühbeck, Patricia Yárnoz‐Esquiroz, Javier Gómez‐Ambrosi, Emma Chávez‐Manzanera, Verónica Vázquez‐Velázquez, Jean‐Michel Oppert, Dimitrios N. Kiortsis, Paolo Sbraccia, Carmine Zoccali, Piero Portincasa, Fabrizio Montecucco   +28 more
wiley   +1 more source

Hepatic lipid composition and stearoyl-coenzyme A desaturase 1 mRNA expression can be estimated from plasma VLDL fatty acid ratios.

Clinical Chemistry, 2009
BACKGROUND Stearoyl-coenzyme A desaturase 1 (SCD1) catalyzes the limiting step of monounsaturated fatty acid synthesis in humans and is an important player in triglyceride generation.
A. Peter, A. Čegan, S. Wagner, R. Lehmann, N. Stefan, A. Königsrainer, I. Königsrainer, H. Häring, E. Schleicher   +8 more
semanticscholar   +1 more source

Concordance‐discordance between apolipoprotein B and lipid biomarkers in predicting 20‐year atherosclerotic cardiovascular disease risk: The ATTICA study (2002–2022)

European Journal of Clinical Investigation, EarlyView.
This study examined the association between 20‐year atherosclerotic cardiovascular disease (ASCVD) risk and discordance among apolipoprotein B100 (apoB) and lipid biomarkers, using established thresholds. ApoB strongly correlated with LDL‐C and non‐HDL‐C, though concordance was limited.
Sofia‐Panagiota Giannakopoulou, Smaragdi Antonopoulou, Fotios Barkas, Evangelos Liberopoulos, Christina Chrysohoou, Petros P. Sfikakis, Christos Pitsavos, Costas Tsioufis, Demosthenes Panagiotakos   +8 more
wiley   +1 more source

Endogenous cholesterol synthesis is associated with VLDL-2 apoB-100 production in healthy humans

Journal of Lipid Research, 2003
Subjects with high plasma cholesterol levels exhibit a high production of VLDL apolipoprotein B-100 (apoB-100), suggesting that cholesterol is a mediator for VLDL production.
Berthil H.C.M.T. Prinsen, Johannes A. Romijn, Peter H. Bisschop, Martina M.J. de Barse, P.Hugh R. Barrett, Marie¨tte Ackermans, Ruud Berger, Ton J. Rabelink, Monique G.M. de Sain-van der Velden   +8 more
doaj  

Expanding our understanding of synucleinopathies: proteinopathy, proteinopenia, and lipidopathy

The FEBS Journal, EarlyView.
Neurodegeneration is thought to arise due to the disruption of the protein homeostasis. In synucleinopathies, alterations in the levels of functional and aggregated aSyn lead to proteinopenia and proteinopathy, respectively. aSyn and β‐glucocerebrosidase are closely linked to lipid metabolism, impacting organelle function and lipidostasis.
Manuel Flores‐León, Tiago F. Outeiro
wiley   +1 more source

Accumulation of large very low density lipoprotein in plasma during intravenous infusion of a chylomicron-like triglyceride emulsion reflects competition for a common lipolytic pathway.

Journal of Lipid Research, 1996
Very low density lipoproteins (VLDL) are produced in the liver and contain apolipoprotein (apo) B-100 and endogenous lipids. By contrast, ingestion of fat leads to formation of chylomicrons containing apoB-48 secreted from the intestine. In this study, a
J Bjorkegren, C J Packard, A Hamsten, D Bedford, M Caslake, L Foster, J Shepherd, P Stewart, F Karpe   +8 more
doaj  

Leptin promoter G2548A variant, elevated plasma leptin levels, and increased risk of Type 2 diabetes with CAD in Iranian patients: A genetic association study

Journal of Diabetes Investigation, EarlyView.
The paper should be of interest to readers in the areas of genetic association, polymorphism, and Type 2 diabetes. ABSTRACT Background Type 2 diabetes mellitus (T2DM) is a significant risk factor for coronary artery disease (CAD). Leptin polymorphism is known to be associated with obesity and Type 2 diabetes mellitus.
Leila Saremi, Nazanin Ahmadi, Fatemeh Feizy, Shirin Lotfipanah, Mohammad Ebrahim Ghaffari, Zohreh Saltanatpour   +5 more
wiley   +1 more source

Causal Effects of Lipids-Related Metabolites on Androgenic Alopecia: A Mendelian Randomization Study

Clinical, Cosmetic and Investigational Dermatology
Lingbo Bi,* Chaofan Wang,* Yimei Du,* Changpei Lu, Min Zhao, Yunbu Ding, Weiling Sun, Weixin Fan Department of Dermatology, Jiangsu Province Hospital and Nanjing Medical University First Affiliated Hospital, Nanjing, People’s Republic of ...
Bi L, Wang C, Du Y, Lu C, Zhao M, Ding Y, Sun W, Fan W   +7 more
doaj