Results 101 to 110 of about 43,360 (234)
Circulation ResearchThe production and secretion of VLDLs (very-low-density lipoproteins) by hepatocytes has a direct impact on liver fat content, as well as the concentrations of cholesterol and triglycerides in the circulation and thus affects both liver and cardiovascular health, respectively. Importantly, insulin resistance, excess caloric intake, and lack of physical
Van Zwol, Willemien +3 more
openaire +1 more source
Clinical &Translational Immunology, Volume 15, Issue 3, 2026.Familial haemophagocytic lymphohistiocytosis (FHL) is a rare, inherited granzyme–perforin system defect that predisposes individuals to haemophagocytic lymphohistiocytosis. This article presents two original case reports of FHL type 2, along with a comprehensive literature review. Together, these elements aim to enhance the current understanding of FHL
Nicolas Perrard +12 more
wiley +1 more source
Endocrinology, Diabetes &Metabolism, Volume 9, Issue 2, March 2026.This meta‐analysis of 25 randomised controlled trials demonstrates that walnut consumption significantly lowers apolipoprotein B levels while showing no significant effects on apolipoprotein A1, systolic blood pressure, or diastolic blood pressure. ABSTRACT Backgrounds Many randomised controlled trials (RCTs) have revealed the benefits of walnut on ...
Vali Musazadeh +4 more
wiley +1 more source
Food Science &Nutrition, Volume 14, Issue 3, March 2026.Salvadora persica methanolic extract exhibited strong antioxidant, hypolipidemic, and hypoglycemic effects in high‐fat diet‐induced hyperlipidemic rats. In vitro antioxidant assays, GC–MS profiling, and in vivo studies confirmed improvements in the lipid profile and in markers of oxidative stress, liver, and kidney function.
Nudrat Khursheed +10 more
wiley +1 more source
Food Science &Nutrition, Volume 14, Issue 3, March 2026.Salvianolic acid B (SALB) is the major water‐soluble bioactive constituent of Salvia miltiorrhiza Bunge, a traditional Asian health‐promoting food, while its therapeutic potential and molecular mechanisms in the pathogenesis of MAFLD remain largely unclear.
Fengyan Huang +8 more
wiley +1 more source
Health Science Reports, Volume 9, Issue 3, March 2026.ABSTRACT Background Substance use, particularly cannabis and alcohol consumption, presents a growing public health challenge in Ghana, with significant implications for both mental and physical health. While the adverse psychological effects of these substances have been extensively studied, their biochemical impact remains inadequately explored ...
Felix Abekah Botchway +6 more
wiley +1 more source
Journal of Extracellular Vesicles, Volume 15, Issue 3, March 2026.During AD progression, EVs derived from APP/PS1 neurons transport APOE into healthy neurons, potentially interacting with neuronal APOE receptors (LRP1, LDLR, VLDLR) to transduction the signaling. This signaling inhibits Rac1‐GTP activation and subsequently downregulates F‐actin polymerization through the Rac1‐N‐WASP‐Arp2/3 pathway.
Yang Yu +4 more
wiley +1 more source
Journal of Intelligent Medicine, Volume 3, Issue 1, Page 47-68, March 2026.Abstract The isoproterenol‐induced myocardial infarction model is a well‐established experimental approach for studying cardiac injury and testing potential protective treatments. By overstimulating beta‐adrenergic receptors, this model closely reproduces key features of human heart attacks, including oxidative damage, calcium imbalance, inflammatory ...
Bushra Imran +5 more
wiley +1 more source
Journal of Inherited Metabolic Disease, Volume 49, Issue 2, March 2026.ABSTRACT Glycogen storage disease type Ia (GSD Ia) is a rare autosomal recessive inherited disorder of carbohydrate metabolism, caused by a deficiency in glucose 6‐phosphatase‐α (G6PC1). Patients primarily suffer from failure to thrive, hepatomegaly, and severe fasting intolerance, biochemically characterized by hypoketotic, hypoglycemia, and ...
Ruiqi Xiao +7 more
wiley +1 more source