Results 161 to 170 of about 59,863 (274)
Phase 3 Randomized Trial Results of DTX401 AAV Gene Therapy for the Treatment of GSDIa
Journal of Inherited Metabolic Disease, Volume 49, Issue 5, September 2026.ABSTRACT Glycogen storage disease type Ia (GSDIa) is a rare, life‐threatening inherited carbohydrate metabolism disorder caused by biallelic pathogenic G6PC gene variants resulting in deficiency of glucose‐6‐phosphatase. DTX401 is an investigational AAV8 vector containing the human G6PC gene. DTX401‐CL301 is a pivotal, phase 3, double‐blind, randomized,
John J. Mitchell +37 more
wiley +1 more source
Sustained estimated VLDL-C exposure is associated with cardiometabolic multimorbidity and foam cell dysfunction: evidence from prospective cohorts and <i>in vitro</i> studies. [PDF]
J Geriatr CardiolWang LZ, Cui KJ, Wang XM, Jia RK, Xie X.
europepmc +1 more source
Legume Science, Volume 8, Issue 3, September 2026.ABSTRACT Chickpea (Cicer arietinum L.) is an important dietary legume worldwide and provides micronutrients and phytochemicals, including phenolics, flavonoids, carotenoids, bioactive peptides, dietary fiber, and resistant starch. This narrative review summarizes evidence from in vitro, animal, and human studies on the potential health relevance of ...
Rohama Shahid +4 more
wiley +1 more source
Correlation Between Superoxide Dismutase and Very-Low-Density Lipoprotein Cholesterol in the Blood of Patients with Uterine Fibroids. [PDF]
Int J Womens HealthDai J +5 more
europepmc +1 more source
, 2010 The goal of the Third Very Large Digital Library workshop is to discuss on-going implementations of Digital Libraries, hence to continue on providing researchers, practitioners and application developers with a forum fostering a constructive exchange among all key actors in the field of Very Large Digital Libraries.
Ioannidis Y., Manghi P., Pagano P.
openaire +1 more source
Melatonin Promotes Improvement in Serum Lipid Levels and Liver Histopathology in Hyperlipidemic Rats
Lipids, Volume 61, Issue 5, Page 583-593, September 2026.ABSTRACT Hyperlipidemia or dyslipidemia is the term used for the increase in lipid levels in blood plasma, usually occurring due to a high‐fat diet associated with a sedentary lifestyle. The increase in lipid levels can cause fatty infiltration in the liver known as hepatic steatosis, which can lead to inflammation, fibrosis, and necrosis consecutively.
Ana Cláudia Carvalho de Sousa +9 more
wiley +1 more source
MedComm, Volume 7, Issue 9, September 2026.The LDL‐C/ApoB ratio, a marker of LDL size, showed significant prognostic value in statin‐treated CAD patients depending on diabetes status. A higher ratio was linked to lower cardiovascular risk only in patients with type 2 diabetes, suggesting it may be a superior biomarker for risk stratification beyond conventional lipids in this high‐risk group ...
Xiaohui Bian +6 more
wiley +1 more source
NMR in Biomedicine, Volume 39, Issue 9, September 2026.1H NMR–based serum metabolomics was employed to identify AMI differential biomarkers and associated metabolic pathways. A diagnostic model evaluated via ROC analysis demonstrated robust performance of these biomarkers, thereby providing novel insights into the pathophysiological mechanisms underlying AMI. ABSTRACT Acute myocardial infarction (AMI) is a
Bing He +7 more
wiley +1 more source
Neuropsychopharmacology Reports, Volume 46, Issue 3, September 2026.Adjunctive aripiprazole may provide modest improvements in lipid parameters and body weight in clozapine‐treated patients with schizophrenia, but evidence for glucose and waist circumference outcomes remains limited. Larger, long‐term randomized controlled trials are needed.
Avtaar Singh, Soban Sadiq
wiley +1 more source