The nuclear liver X receptor (LXR) regulates multiple aspects of cholesterol, triacylglycerol (TG), and carbohydrate metabolism. Activation of LXR induces the expression of genes encoding enzymes involved in de novo lipogenesis (DNL) resulting in hepatic
Aldo Grefhorst, Elizabeth J. Parks
doaj
Pima Indians have a high prevalence of hyperinsulinemia, obesity, and diabetes, but they have low plasma cholesterol levels, reduced low density lipoprotein synthesis, and little arteriosclerotic heart disease.
B V Howard+8 more
doaj
Postprandial chylomicrons and VLDLs in severe hypertriacylglycerolemia are lowered more effectively than are chylomicron remnants after treatment with n−3 fatty acids [PDF]
Sabine Westphal+4 more
openalex +1 more source
VLDL lipidomics reveals hepatocellular lipidome changes in metabolic dysfunction-associated steatotic liver disease. [PDF]
Guardamino Ojeda D+10 more
europepmc +1 more source
Hypertriglyceridemic VLDL Downregulates Tissue Plasminogen Activator Gene Transcription Through cis -Repressive Region(s) in the Tissue Plasminogen Activator Promoter in Cultured Human Endothelial Cells [PDF]
Edlue M. Tabengwa+3 more
openalex +1 more source
Causal relationships between metabolic syndrome, plasma metabolites, and female reproductive diseases: insights from a two-step mendelian randomization approach. [PDF]
Li L, Ma J, Sun N, Hu P, Lin Y, Zhang Q.
europepmc +1 more source
LPS-binding protein circulates in association with apoB-containing lipoproteins and enhances endotoxin-LDL/VLDL interaction [PDF]
Anita Vreugdenhil+4 more
openalex +1 more source
Selective Hepatic Insulin Resistance, VLDL Overproduction, and Hypertriglyceridemia
J. Sparks, C. Sparks, K. Adeli
semanticscholar +1 more source