Results 61 to 70 of about 66,180 (284)

Exploring the Molecular Pathways Underlying the Anti‐Diabetic Effects of Millets

Food Safety and Health, EarlyView.
Millet consumption may modulate gluconeogenesis and glycolysis, enhance glucose transporter activity, increase leptin levels, inhibit the NF‐κB pathway, and mitigate oxidative and nitrosative stress. ABSTRACT Diabetes mellitus (DM) is a metabolic disorder characterized by hyperglycemic conditions resulting from inadequate insulin production or ...
Akash Kumar, Nidhi N. Shah, Mehul R. Chorawala, Rekha Kaushik, Bhupendra Prajapati, Rahul Mehra   +5 more
wiley   +1 more source

Adrenal cell aldosterone production is stimulated by very-low-density lipoprotein (VLDL).

Endocrinology, 2012
Very low-density lipoproteins (VLDL) are a class of large lipoprotein synthesized in the liver. The key function of VLDL, in vivo, is to carry triglyceride from the liver to adipose tissue.
Yewei Xing, W. Rainey, J. Apolzan, O. Francone, Ruth B. S. Harris, W. Bollag   +5 more
semanticscholar   +1 more source

Exploring the Antidiabetic and Lipid‐Lowering Properties of Nepali Wild Turmeric (Curcuma aromatica): A Potential Natural Remedy

Food Safety and Health, EarlyView.
Curcuma aromatica rhizome ethanolic extracts (400 mg/kg) showed hypoglycemic and hypolipidemic activities in alloxan‐induced diabetic rats, comparable to standard drugs in reducing blood glucose levels. The extracts reduced serum cholesterol and triglycerides, increased HDL levels, and prevented weight loss.
Salma Khadka, Tshoisang Vaal, Sanjit Gurung, Keshav Dhakal, Ramesh Raj Padhaya, Sailendra Chaudhary, Bipindra Pandey   +6 more
wiley   +1 more source

Hepatic ABCA1 and VLDL triglyceride production

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2012
Elevated plasma triglyceride (TG) and reduced high density lipoprotein (HDL) concentrations are prominent features of metabolic syndrome (MS) and type 2 diabetes (T2D). Individuals with Tangier disease also have elevated plasma TG concentrations and a near absence of HDL, resulting from mutations in ATP binding cassette transporter A1 (ABCA1), which ...
Liu, Mingxia, Chung, Soonkyu, Shelness, Gregory S., Parks, John S.   +3 more
openaire   +5 more sources

Effects of Electronegative VLDL on Endothelium Damage in Metabolic Syndrome

Diabetes Care, 2012
OBJECTIVE Biochemical heterogeneity governs functional disparities among lipoproteins. We examined charge-defined VLDL subfractions in metabolic syndrome (MetS) to determine whether their increased electronegativity is associated with increased ...
Chu‐Huang Chen, Jonathan T. Lu, Shu-hua Chen, R. Huang, H. R. Yilmaz, Jianwen Dong, M. Elayda, R. Dixon, Chao-yuh Yang   +8 more
semanticscholar   +1 more source

Regulation of VLDL synthesis and secretion in the liver [PDF]

Reproduction Nutrition Development, 1996
The production of very low density lipoproteins (VLDL) by the liver results from very complex processes that involve coordinated mechanisms of both protein and lipid synthesis and packaging. Alterations in these metabolic functions can cause negative effects on the health of human subjects or animals.
Gruffat, Dominique, Durand, Denys, Graulet, Benoit, Bauchart, Dominique   +3 more
openaire   +5 more sources

Decreases in the serum VLDL-TG/non-VLDL-TG ratio from early stages of chronic hepatitis C: alterations in TG-rich lipoprotein levels. [PDF]

PLoS ONE, 2011
BACKGROUND: The liver secretes very-low-density lipoproteins (VLDLs) and plays a key role in lipid metabolism. Plasma total triglyceride (TG) level variations have been studied in patients with hepatitis C virus (HCV)-related chronic hepatitis (CH-C ...
Motoi Nishimura, Haruna Yamamoto, Toshihiko Yoshida, Masanori Seimiya, Yuji Sawabe, Kazuyuki Matsushita, Hiroshi Umemura, Kazuyuki Sogawa, Hirotaka Takizawa, Osamu Yokosuka, Fumio Nomura   +10 more
doaj   +1 more source

Effects of a two‐night hospitalization program as a specific health guidance on obesity and cardiovascular disease risk factors

Journal of General and Family Medicine, EarlyView.
Abstract Background To assess the effects of a two‐night hospitalization program conducted at our hospital as part of a domestic health guidance system. This program is designed for lifestyle modification within a health checkup framework for metabolic syndrome. Methods This is a single‐center, retrospective observational study. We reviewed the medical
Maki Okazaki, Takeshi Katsuki, Hideaki Kurata, Shinichi Tanaka, Hajime Tanaka, Toshihide Kawai   +5 more
wiley   +1 more source

Ubiquitination regulates the assembly of VLDL in HepG2 cells and is the committing step of the apoB-100 ERAD pathway[S]

Journal of Lipid Research, 2011
Apolipoprotein B-100 (apoB-100) is degraded by endoplasmic reticulum-associated degradation (ERAD) when lipid availability limits assembly of VLDLs. The ubiquitin ligase gp78 and the AAA-ATPase p97 have been implicated in the proteasomal degradation of ...
E. Fisher, Neeraj A. Khanna, R. McLeod
semanticscholar   +1 more source

Lipid and lipoprotein particle profiles in patients with type 2 diabetes mellitus: A comparative study between highlanders and lowlanders

Lipids, EarlyView.
Abstract The lipid profiles of highlanders and lowlanders differ. However, studies of the lipid profiles of patients with type 2 diabetes mellitus (T2DM) living at high altitudes are limited. This study aimed to compare lipid profiles and lipoprotein particles in individuals with T2DM permanently residing in the Tibetan Plateau and those residing in ...
Chenghui Zhang, Rong Du, Suyuan Wang, Yan Ye, Xueping Sun, Yunhong Wu, Mingxia Li   +6 more
wiley   +1 more source