Results 71 to 80 of about 43,360 (234)
Hepatic ABCA1 and VLDL triglyceride production
Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2012 Elevated plasma triglyceride (TG) and reduced high density lipoprotein (HDL) concentrations are prominent features of metabolic syndrome (MS) and type 2 diabetes (T2D). Individuals with Tangier disease also have elevated plasma TG concentrations and a near absence of HDL, resulting from mutations in ATP binding cassette transporter A1 (ABCA1), which ...
Liu, Mingxia +3 more
openaire +4 more sources
Sensory Neuroscience, EarlyView.ABSTRACT To explore associations of vestibular disorders with all‐cause and cause‐specific dementia and underlying biological mechanisms/neuroimaging changes. A population‐based cohort study of 406,348 UK Biobank participants was conducted. Inverse probability of treatment weighting (IPTW) balanced baseline covariates, and Cox proportional hazards ...
Xiaofei Li +15 more
wiley +1 more source
Journal of Lipid Research, 1991 Two procedures were used to isolate hepatocytic Golgi fractions from rat liver. One procedure yields a light Golgi fraction (GF1 + 2) and the other “intact” stacks of cisternae.
RL Hamilton, A Moorehouse, RJ Havel
doaj +1 more source
Small, EarlyView.A novel affinity‐based mesh filtration system, ApoFilter, enables selective removal of plasma lipoproteins via sequential aptamer‐functionalized layers targeting ApoA1 and ApoB100. While EVs pass through unimpeded, (V)LDL and HDL are rapidly depleted.
SoYoung Jeon, YongWoo Kim, Sehyun Shin
wiley +1 more source
Energy expenditure, insulin, and VLDL-triglyceride production in humans
Journal of Lipid Research, 2006 Hypertriglyceridemia is considered a cardiovascular risk factor in diabetic and nondiabetic subjects. In this study, we aimed to determine potential regulators of very low density lipoprotein-triglyceride (TG) production.
Lars C. Gormsen +5 more
doaj +1 more source
Mature VLDL Particles Exit the Golgi in Distinct Post‐Golgi VLDL Vesicles
The FASEB Journal, 2013 Post‐Golgi transport of VLDL is crucial for maintaining normal triacylglycerol (TAG) homeostasis of hepatocytes, however, nothing is known about the exit of VLDLs from the Golgi. To study this important process, we established an in vitro Golgi‐budding assay to examine the formation of Golgi‐derived VLDL vesicles using hepatic Golgi containing [3H]TAG ...
Shadab A Siddiqi +2 more
openaire +1 more source
Advances in cholesterol and lipoproteins detection for healthcare: A review
VIEW, EarlyView.Cholesterol is one of the main biomarkers related to the development of cardiovascular diseases. Its detection still relies on traditional methods of analysis, such as gas and liquid chromatographies. Detection of free cholesterol in saliva with redox or enzymatic sensors or detection of lipoproteins in blood with aptamer sensors are currently the most
Jacopo Giaretta +7 more
wiley +1 more source
Journal of Lipid Research, 1998 Studying the effects of dietary fish oil on VLDL metabolism in humans is subject to both large intra- and interindividual variability. In the present study we therefore used hyperlipidemic apolipoprotein (APO) E*3-Leiden mice, which have impaired ...
Bart J.M. van Vlijmen +5 more
doaj +1 more source
Allergy, EarlyView.ABSTRACT Background Allergic rhinitis (AR) impacts quality of life, work and school productivity. Over the last years, an important body of evidence resulting from mHealth data has led to a better understanding of AR. Such advances have motivated an EAACI‐endorsed update of the Allergic Rhinitis and its Impact on Asthma (ARIA) guidelines (ARIA 2024 ...
Bernardo Sousa‐Pinto +252 more
wiley +1 more source
British Journal of Pharmacology, EarlyView.Cannabidiol (CBD) and cannabigerol (CBG) alleviate hepatic steatosis in obese mice by shifting energy buffering towards phosphocreatine and enhancing lysosomal lipid degradation and trafficking. These effects are associated with increased creatine kinase activity and lysobisphosphatidic acid (LBPA) levels, highlighting a previously unrecognised ...
Radka Kočvarová +12 more
wiley +1 more source