Results 41 to 50 of about 53,616 (262)

The M, E, and N structural proteins of the severe acute respiratory syndrome coronavirus are required for efficient assembly, trafficking, and release of virus-like particles [PDF]

, 2008
Copyright @ 2008 American Society for Microbiology.The production of virus-like particles (VLPs) constitutes a relevant and safe model to study molecular determinants of virion egress.
Altmeyer, R, Bruzzone, R, Chan, CM, Escriou, N, Kien, F, Lo, J, Nal, B, Nicholls, JM, Peiris, JSM, Siu, YL, Teoh, KT, Tsao, SW   +11 more
core   +5 more sources

Vaccination with virus-like particles containing hemagglutinin protects the lungs of mice with postifluenza bacterial pneumonia: virological, microbiological and clinical data

Вопросы вирусологии, 2020
Introduction. Influenza is a severe viral disease, a frequent complication of which is a secondary bacterial pneumonia. Influenza vaccines prevent secondary bacterial complications.
I. N. Falynskova, A. Yu. Egorov, A. V. Poddubikov, N. O. Vartanova, N. P. Kartashova, E. A. Glubokova, V. A. Mkhitarov, D. S. Dzhalilova, O. V. Makarova, I. A. Leneva   +9 more
doaj   +1 more source

Superior neutralizing antibody response and protection in mice vaccinated with heterologous DNA prime and virus like particle boost against HPAI H5N1 virus. [PDF]

PLoS ONE, 2011
BACKGROUND: Although DNA plasmid and virus-like particle (VLP) vaccines have been individually tested against highly pathogenic avian influenza (HPAI) H5N1 viruses, the combination of both vaccines into a heterologous prime-boost strategy against HPAI ...
Heng Ding, Cheguo Tsai, Ramona Alikiiteaga Gutiérrez, Fan Zhou, Philippe Buchy, Vincent Deubel, Paul Zhou   +6 more
doaj   +1 more source

Dry Formulation of Virus-Like Particles in Electrospun Nanofibers

Vaccines, 2021
Biologics can be combined with liquid polymer materials and electrospun to produce a dry nanofibrous scaffold. Unlike spray-drying and freeze-drying, electrospinning minimizes the physiological stress on sensitive materials, and nanofiber mat properties ...
Sasheen Dowlath, Katrin Campbell, Farah Al-Barwani, Vivienne L. Young, Sarah L. Young, Greg F. Walker, Vernon K. Ward   +6 more
doaj   +1 more source

Impedance-compensated grid synchronisation for extending the stability range of weak grids with voltage source converters [PDF]

, 2016
This paper demonstrates how the range of stable power transfer in weak grids with voltage source converters (VSCs) can be extended by modifying the grid synchronisation mechanism of a conventional synchronous reference frame phase locked loop (PLL).
D'Arco, Salvatore, Molinas Cabrera, Marta, Rodríguez Cortés, Pedro, Suul, Jon Are   +3 more
core   +2 more sources

Simultaneous Immunization with Multivalent Norovirus VLPs Induces Better Protective Immune Responses to Norovirus than Sequential Immunization

Viruses, 2019
Human noroviruses (NoVs) are a genetically diverse, constantly evolving group of viruses. Here, we studied the effect of NoV pre-existing immunity on the success of NoV vaccinations with genetically close and distant genotypes.
Maria Malm, Timo Vesikari, Vesna Blazevic   +2 more
doaj   +1 more source

Enhanced Immunogenicity of an Influenza Ectodomain Matrix-2 Protein Virus-like Particle (M2e VLP) Using Polymeric Microparticles for Vaccine Delivery

Viruses, 2022
In this study, we demonstrate how encapsulating a conserved influenza ectodomain matrix-2 protein virus-like particle (M2e5x VLP) into a pre-crosslinked bovine serum albumin (BSA) polymeric matrix enhances in vitro antigen immunogenicity and in vivo ...
Keegan Braz Gomes, Ipshita Menon, Priyal Bagwe, Lotika Bajaj, Sang-Moo Kang, Martin J. D’Souza   +5 more
doaj   +1 more source

VLP‐factory™ and ADDomer©: Self‐assembling Virus‐Like Particle (VLP) Technologies for Multiple Protein and Peptide Epitope Display

Current Protocols, 2021
Virus‐like particles (VLPs) play a prominent role in vaccination as safe and highly versatile alternatives to attenuated or inactivated viruses or subunit vaccines.
Duygu Sari-Ak, J. Bufton, K. Gupta, F. Garzoni, Daniel J. Fitzgerald, C. Schaffitzel, I. Berger   +6 more
semanticscholar   +1 more source

The safety of attenuated and recombinant nasal influenza vaccines in terms of the development of secondary bacterial superinfection

Журнал микробиологии, эпидемиологии и иммунобиологии, 2019
Introduction. Influenza is a severe viral disease. The most common post-influenza complication is pneumonia. Earlier, we developed an experimental mouse model of viralbacterial pneumonia induced by successive infection with influenza virus and St. aureus,
N. R. Makhmudova, I. A. Leneva, N. V. Larionova, A. V. Poddubikov, I. N. Falynskova, N. P. Kartashova, O. A. Svitich   +6 more
doaj   +1 more source

Promotion of Cellular and Humoral Immunity against Foot-and-Mouth Disease Virus by Immunization with Virus-Like Particles Encapsulated in Monophosphoryl Lipid A and Liposomes

Vaccines, 2020
Virus-like particles (VLPs) have emerged as promising vaccine candidates against foot-and-mouth disease (FMD). However, such vaccines provide a relatively low level of protection against FMD virus (FMDV) because of their poor immunogenicity.
Woo Sik Kim, Yong Zhi, Huichen Guo, Eui-Baek Byun, Jae Hyang Lim, Ho Seong Seo   +5 more
doaj   +1 more source