Results 51 to 60 of about 21,570 (220)
BMC Microbiology, 2008 Background Mycoplasma agalactiae is the main cause of contagious agalactia, a serious disease of sheep and goats, which has major clinical and economic impacts. Previous studies of M.
Ayling Roger D +5 more
doaj +1 more source
Mucin variable number tandem repeat polymorphisms and severity of cystic fibrosis lung disease: significant association with MUC5AC. [PDF]
PLoS ONE, 2011 Variability in cystic fibrosis (CF) lung disease is partially due to non-CFTR genetic modifiers. Mucin genes are very polymorphic, and mucins play a key role in the pathogenesis of CF lung disease; therefore, mucin genes are strong candidates as genetic ...
Xueliang Guo +11 more
doaj +1 more source
European Journal of Haematology, EarlyView.ABSTRACT Background Sickle cell disease (SCD) is a chronic and life‐limiting hemoglobin and systemic vascular disease. While over 1000 people have undergone hematopoietic cell transplantation (HCT) over the last 40 years, long‐term disease‐specific and health‐related quality of life data are lacking.
Gregory M. T. Guilcher +20 more
wiley +1 more source
BMC Genomics, 2015 VNTR (Variable Number of Tandem Repeats) composite retrotransposons - SVA (SINE-R-VNTR-Alu), LAVA (LINE-1-Alu-VNTR-Alu), PVA (PTGR2-VNTR-Alu) and FVA (FRAM-VNTR-Alu) - are specific to hominoid primates.
I. Lupan +3 more
semanticscholar +1 more source
Characterization of three VNTR systems at D21S112
Genomics, 1992 D21S112 is a highly polymorphic marker on the long arm of chromosome 21. Our analysis of this locus indicated the presence of three VNTR systems. We estimated the heterozygosity of each system and sequenced one of the repetitive regions. Utilizing PCR, we demonstrated that the sequenced VNTR is responsible for the system with the highest level of ...
N, Takaesu, S, Newfeld, T, Hassold
openaire +2 more sources
Genomic Medicine Sweden: Advancing precision medicine at the national level
Journal of Internal Medicine, EarlyView.Abstract High‐throughput sequencing has transformed clinical diagnostics of rare diseases (RD), cancer and infectious diseases by enabling the identification of disease‐causing genetic alterations and facilitating individualised treatment and care.
Anders Edsjö +58 more
wiley +1 more source
Technologies for engineering repetitive DNA
Quantitative Biology, Volume 14, Issue 3, September 2026.Abstract Repetitive DNA, a fundamental architectural element of genomes, is widespread across organisms and comprises about 54% of the human genome. With advances in long‐read sequencing and bioinformatics approaches, highly repetitive sequences can now be characterized in depth.
Shuting Ma, Yali Cui, Yi Wu
wiley +1 more source
Possible Association of IL-4 VNTR Polymorphism with Susceptibility to Preeclampsia
BioMed Research International, 2014 Preeclampsia (PE) is a pregnancy-specific disorder that results in maternal mortality and morbidity. Growing evidence indicated that cytokines are involved in the pathogenesis of PE and interleukin-4 VNTR polymorphism could be implicated in altering the ...
S. Salimi +4 more
semanticscholar +1 more source
Animal Genetics, Volume 57, Issue 4, August 2026.ABSTRACT Canine mammary tumours (CMTs) are one of the most frequently observed malignancies in female dogs. Many studies have investigated epigenetic changes in CMT at the nuclear level, yet the role of mtDNA methylation, particularly in the D‐loop region, remains largely unexplored.
Krzysztof Kowal +5 more
wiley +1 more source
Genetic Heterogeneity of Francisella tularensis Subspecies mediasiatica Strains
Проблемы особо опасных инфекцийThe aim of the study was to conduct comparative phylogenetic analysis of Francisella tularensis subsp. mediasiatica strains isolated in different territories of contemporary Republics of Kazakhstan, Uzbekistan, Altai Territory, and the Altai Republic in ...
V. M. Sorokin +5 more
doaj +1 more source