Results 31 to 40 of about 21,570 (220)

The shortcut of mycobacterial interspersed repetitive unit-variable number tandem repeat typing for Mycobacterium tuberculosis differentiation

open access: yesFrontiers in Microbiology, 2022
The 24-loci mycobacterial interspersed repetitive unit-variable number tandem repeat (MIRU-VNTR) genotyping has been used as an international standard method for Mycobacterium tuberculosis (Mtb) genotyping. However, different optimized VNTR loci sets for
Shima Hadifar   +15 more
doaj   +1 more source

trfermikit: a tool to discover VNTR-associated deletions [PDF]

open access: yesBioinformatics, 2021
AbstractSummaryWe present trfermikit, a software tool designed to detect deletions larger than 50 bp occurring in Variable Number Tandem Repeats using Illumina DNA sequencing reads. In such regions, it achieves a better tradeoff between sensitivity and false discovery than a state-of-the-art structural variation caller, Manta and complements it by ...
Peter McHale, Aaron R. Quinlan
openaire   +2 more sources

METHODOLOGICAL APPROACHES TO MYCOBACTERIUM TUBERCULOSIS GENOTYPING FOR EVOLUTIONARY AND EPIDEMIOLOGICAL RESEARCH

open access: yesИнфекция и иммунитет, 2014
. Current genome evolution of Mycobacterium tuberculosis is marked by virtual absence of the lateral gene transfer leading to the clonal population of this species consisting of separate genetic families. Standard typing method of M. tuberculosis (IS6110-
I. V. Mokrousov
doaj   +1 more source

MIRU-profiler: a rapid tool for determination of 24-loci MIRU-VNTR profiles from assembled genomes of Mycobacterium tuberculosis

open access: yesPeerJ, 2018
Background Tuberculosis (TB) resulted in an estimated 1.7 million deaths in the year 2016. The disease is caused by the members of Mycobacterium tuberculosis complex, which includes Mycobacterium tuberculosis, Mycobacterium bovis and other closely ...
Rahim Rajwani, Sheeba Shehzad, G. Siu
semanticscholar   +1 more source

Yersinia pseudotuberculosis Typing Using Multi-Locus Variable-Number Tandem Repeat Analysis

open access: yesПроблемы особо опасных инфекций, 2015
Estimated has been efficacy of MLVA25 method, used for differentiation and clusterization of Yersinia pestis strains, in reference to Yersinia pseudotuberculosis strains, as well as the search of Y. pseudotuberculosis strains mostly closely related to Y.
V. V. Evseeva   +3 more
doaj   +1 more source

Characterization of the COL2A1 VNTR Polymorphism

open access: yesGenomics, 1993
The variable number of tandem repeat (VNTR) region 3' to the collagen type II gene (COL2A1) was amplified in vitro by the polymerase chain reaction. Subsequent high-resolution gel electrophoresis showed that the five earlier reported alleles could be further subtyped.
E S, Berg, B, Olaisen
openaire   +2 more sources

Extreme enrichment of VNTR-associated polymorphicity in human subtelomeres: genes with most VNTRs are predominantly expressed in the brain [PDF]

open access: yesTranslational Psychiatry, 2020
AbstractThe human genome harbors numerous structural variants (SVs) which, due to their repetitive nature, are currently underexplored in short-read whole-genome sequencing approaches. Using single-molecule, real-time (SMRT) long-read sequencing technology in combination with FALCON-Unzip, we generated a de novo assembly of the diploid genome of a 115 ...
Linthorst, Jasper   +6 more
openaire   +4 more sources

Setting-up of the Database on the Nucleotide Sequences of the Genomes of the Strains of Bacterial and Viral Infections Agents of the I–II Pathogenicity Groups

open access: yesПроблемы особо опасных инфекций, 2013
Set-up is database containing characteristics of variable tandem repeats, oligo-nucleotide primers and probes of the genomes of the strains bacterial and viral infections agents of the I-II pathogenicity groups.
Yu. I. Yashechkin   +3 more
doaj   +1 more source

Application of Bacillus anthracis Molecular Typing Methods by the Reference Center for the Anthrax Agent Monitoring

open access: yesПроблемы особо опасных инфекций, 2011
Presented are the results of B. anthracis molecular typing of in the scope of work of the Reference center for the anthrax agent monitoring. Summarized is the experience of genotyping application in epidemiological investigation of anthrax outbreaks ...
A. G. Ryazanova   +4 more
doaj   +1 more source

Functional Domains of Autoimmune Regulator (AIRE) Modulate INS-VNTR Transcription in Human Thymic Epithelial Cells*

open access: yesJournal of Biological Chemistry, 2016
INS-VNTR (insulin-variable number of tandem repeats) and AIRE (autoimmune regulator) have been associated with the modulation of insulin gene expression in thymus, which is essential to induce either insulin tolerance or the development of insulin ...
A. E. Sparks   +3 more
semanticscholar   +1 more source

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