Results 31 to 40 of about 12,118 (162)

Evaluation of spoligotyping, SNPs and customised MIRU-VNTR combination for genotyping Mycobacterium tuberculosis clinical isolates in Madagascar.

PLoS ONE, 2017
BackgroundCombining different molecular typing methods for Mycobacterium tuberculosis complex (MTBC) can be a powerful tool for molecular epidemiology-based investigation of TB. However, the current standard method that provides high discriminatory power
Rondroarivelo Rasoahanitralisoa, Niaina Rakotosamimanana, David Stucki, Christophe Sola, Sebastien Gagneux, Voahangy Rasolofo Razanamparany   +5 more
doaj   +1 more source

Yersinia pseudotuberculosis Typing Using Multi-Locus Variable-Number Tandem Repeat Analysis

Проблемы особо опасных инфекций, 2015
Estimated has been efficacy of MLVA25 method, used for differentiation and clusterization of Yersinia pestis strains, in reference to Yersinia pseudotuberculosis strains, as well as the search of Y. pseudotuberculosis strains mostly closely related to Y.
V. V. Evseeva, M. E. Platonov, S. V. Dentovskaya, A. P. Anisimov   +3 more
doaj   +1 more source

Mucin variable number tandem repeat polymorphisms and severity of cystic fibrosis lung disease: significant association with MUC5AC. [PDF]

PLoS ONE, 2011
Variability in cystic fibrosis (CF) lung disease is partially due to non-CFTR genetic modifiers. Mucin genes are very polymorphic, and mucins play a key role in the pathogenesis of CF lung disease; therefore, mucin genes are strong candidates as genetic ...
Xueliang Guo, Rhonda G Pace, Jaclyn R Stonebraker, Clayton W Commander, Anthony T Dang, Mitchell L Drumm, Ann Harris, Fei Zou, Dallas M Swallow, Fred A Wright, Wanda K O'Neal, Michael R Knowles   +11 more
doaj   +1 more source

Technologies for engineering repetitive DNA

Quantitative Biology, Volume 14, Issue 3, September 2026.
Abstract Repetitive DNA, a fundamental architectural element of genomes, is widespread across organisms and comprises about 54% of the human genome. With advances in long‐read sequencing and bioinformatics approaches, highly repetitive sequences can now be characterized in depth.
Shuting Ma, Yali Cui, Yi Wu
wiley   +1 more source

Setting-up of the Database on the Nucleotide Sequences of the Genomes of the Strains of Bacterial and Viral Infections Agents of the I–II Pathogenicity Groups

Проблемы особо опасных инфекций, 2013
Set-up is database containing characteristics of variable tandem repeats, oligo-nucleotide primers and probes of the genomes of the strains bacterial and viral infections agents of the I-II pathogenicity groups.
Yu. I. Yashechkin, E. V. Naydenova, T. V. Bugorkova, S. A. Shcherbakova   +3 more
doaj   +1 more source

Diabetic Peripheral Neuropathy: Molecular Staging, Risk Factors, Therapeutics, and Emerging Trends

Med Research, Volume 2, Issue 2, Page 309-342, June 2026.
The heterogeneous landscape of DPN can be unified through a tripartite pathogenic model encompassing progressive stages of metabolic dysregulation, chronic inflammation, and overt neuronal damage. Within this framework, six clinical subtypes were identified, namely, hyperglycemia‐driven, dyslipidemia‐driven, inflammation‐driven, dysvascularity‐driven ...
Xiaofeng Dai, Mingze Tang
wiley   +1 more source

Application of Bacillus anthracis Molecular Typing Methods by the Reference Center for the Anthrax Agent Monitoring

Проблемы особо опасных инфекций, 2011
Presented are the results of B. anthracis molecular typing of in the scope of work of the Reference center for the anthrax agent monitoring. Summarized is the experience of genotyping application in epidemiological investigation of anthrax outbreaks ...
A. G. Ryazanova, E. I. Eremenko, O. I. Tsygankova, E. A. Tsygankova, A. N. Kulichenko   +4 more
doaj   +1 more source

Characterization of three VNTR systems at D21S112

Genomics, 1992
D21S112 is a highly polymorphic marker on the long arm of chromosome 21. Our analysis of this locus indicated the presence of three VNTR systems. We estimated the heterozygosity of each system and sequenced one of the repetitive regions. Utilizing PCR, we demonstrated that the sequenced VNTR is responsible for the system with the highest level of ...
N, Takaesu, S, Newfeld, T, Hassold
openaire   +2 more sources

cuteHap: Haplotype‐Aware Structural Variant Detection in Phased Long‐Read Sequencing Data

Advanced Science, Volume 13, Issue 22, 17 April 2026.
cuteHap is a haplotype‐aware structural variant detection method designed for phased long‐read sequencing. By employing self‐adaptive clustering and credibility‐prioritized beam search algorithms, cuteHap generates accurate haplotype‐resolved calls and outperforms state‐of‐the‐art tools.
Shuqi Cao, Yadong Liu, Miao Cui, Runtian Gao, Weimin Guo, Guohua Wang, Yadong Wang, Tao Jiang   +7 more
wiley   +1 more source

Pan‐3D Genome Analysis Reveals the Roles of Structural Variation in Chicken Chromatin Architectures, Domestication and Production Traits

Advanced Science, Volume 13, Issue 24, 27 April 2026.
This study firstly presents a comprehensive and high‐resolution pan‐3D genome resource in chicken. Our findings reveal the role of structural variations in 3D genome architectures, and how they influence the domestication process and production traits at the 3D genome level.
Zhen Zhou, Danfeng Cai, Changbin Zhao, Siyu Zhang, Jiahao Li, Zhaofeng Zhang, Shaofen Kong, Xin Yang, Xiaoli Zhou, Farhad Bordbar, Fayi Chen, Yaohuan Xu, Zhe Zhang, Lihong Gu, Zhenhui Li, Xiquan Zhang, Wen Luo, Jingting Shu, Bolin Cai, Qinghua Nie   +19 more
wiley   +1 more source