EBioMedicine, 2018 Background: Mycobacterial Interspersed Repetitive Unit-Variable Number Tandem Repeat (MIRU-VNTR) typing is widely used in high-income countries to determine Mycobacterium tuberculosis relatedness. Whole-genome sequencing (WGS) is known to deliver greater
Derrick W Crook +2 more
exaly +4 more sources
The Role of Interleukin-4 VNTR Polymorphism in Dysmenorrhea Development
Haseki Tıp Bülteni, 2020 Aim:Primary dysmenorrhea (PD) is among the most common gynecological diseases in young women presenting to emergency department. It has been shown that cytokines played roles in PD pathogenesis.
Mehmet Esen +3 more
doaj +2 more sources
ACAN Gene VNTR Polymorphism and Intervertebral Disc Degeneration in a Turkish Population
Haseki Tıp Bülteni, 2020 Aim:Intervertebral disc degeneration (IVDD) is caused by several genetic and environmental factors. Aggrecan is the major component of intervertebral disk matrix proteoglycan with multiple functional domains.
Tuba Öz +5 more
doaj +2 more sources
Comparison between RFLP and MIRU-VNTR genotyping of Mycobacterium tuberculosis strains isolated in Stockholm 2009 to 2011. [PDF]
PLoS ONE, 2014 Our aim was to analyze the difference between methods for genotyping of Mycobacterium tuberculosis complex isolates. We collected genotyping results from Restriction Fragment Length Polymorphism (RFLP) and Mycobacterial Interspersed Repetitive Units ...
Jerker Jonsson +6 more
doaj +2 more sources
An Intronic VNTR Affects Splicing of ABCA7 and Increases Risk of Alzheimer’s Disease
Acta Neuropathologica, 2018 Mutations leading to premature termination codons in ATP-Binding Cassette Subfamily A Member 7 (ABCA7) are high penetrant risk factors of Alzheimer’s disease (AD).
Arne De Roeck +2 more
exaly +2 more sources
PLoS ONE, 2017 BackgroundCombining different molecular typing methods for Mycobacterium tuberculosis complex (MTBC) can be a powerful tool for molecular epidemiology-based investigation of TB. However, the current standard method that provides high discriminatory power
Rondroarivelo Rasoahanitralisoa +5 more
doaj +2 more sources
Evaluation of Customised Lineage-Specific Sets of MIRU-VNTR Loci for Genotyping Mycobacterium tuberculosis Complex Isolates in Ghana [PDF]
PLoS ONE, 2014 Background Different combinations of variable number of tandem repeat (VNTR) loci have been proposed for genotyping Mycobacterium tuberculosis complex (MTBC). Existing VNTR schemes show different discriminatory capacity among the six human MTBC lineages.
A. Asante-Poku +5 more
semanticscholar +2 more sources
Single molecule real time sequencing in ADTKD-MUC1 allows complete assembly of the VNTR and exact positioning of causative mutations [PDF]
Scientific Reports, 2018 Recently, the Mucin-1 (MUC1) gene has been identified as a causal gene of autosomal dominant tubulointerstitial kidney disease (ADTKD). Most causative mutations are buried within a GC-rich 60 basepair variable number of tandem repeat (VNTR), which ...
A. Wenzel +17 more
semanticscholar +2 more sources
Evolutionary history of the PER3 variable number of tandem repeats (VNTR): idiosyncratic aspect of primate molecular circadian clock. [PDF]
PLoS ONE, 2014 The PER3 gene is one of the clock genes, which function in the core mammalian molecular circadian system. A variable number of tandem repeats (VNTR) locus in the 18th exon of this gene has been strongly associated to circadian rhythm phenotypes and sleep
Flávia Cal Sabino +7 more
doaj +2 more sources
Cell GenomicsSummary: Variable number tandem repeat (VNTR) is a pervasive and highly mutable genetic feature that varies in both length and repeat sequence. Despite the well-studied copy-number variants, the functional impacts of repeat motif polymorphisms remain ...
Xiaoyu Yan, Shunmin He, Song Tingrui
exaly +3 more sources