Results 41 to 50 of about 17,479 (163)

Application of Bacillus anthracis Molecular Typing Methods by the Reference Center for the Anthrax Agent Monitoring

Проблемы особо опасных инфекций, 2011
Presented are the results of B. anthracis molecular typing of in the scope of work of the Reference center for the anthrax agent monitoring. Summarized is the experience of genotyping application in epidemiological investigation of anthrax outbreaks ...
A. G. Ryazanova, E. I. Eremenko, O. I. Tsygankova, E. A. Tsygankova, A. N. Kulichenko   +4 more
doaj   +1 more source

Functional Domains of Autoimmune Regulator (AIRE) Modulate INS-VNTR Transcription in Human Thymic Epithelial Cells*

Journal of Biological Chemistry, 2016
INS-VNTR (insulin-variable number of tandem repeats) and AIRE (autoimmune regulator) have been associated with the modulation of insulin gene expression in thymus, which is essential to induce either insulin tolerance or the development of insulin ...
A. E. Sparks, Chiachen Chen, M. Breslin, M. Lan   +3 more
semanticscholar   +1 more source

Development of a technique for molecular typing of Bacillus anthracis strains using new VNTR and INDEL markers

Журнал микробиологии, эпидемиологии и иммунобиологии
Introduction. Bacillus anthracis, the pathogen of a particularly dangerous zoonotic disease known as anthrax, requires strict epidemiological control and is characterized by high genetic homogeneity, which necessitates the development of genotyping ...
Grigorii A. Pechkovskii, Evgeny I. Eremenko, Alla G. Ryazanova, Sergey V. Pisarenko, Nikolay A. Shapakov, Lyudmila Yu. Aksenova, Olga V. Semenova, Lyudmila D. Timchenko, Alexander N. Kulichenko   +8 more
doaj   +1 more source

A 40-bp VNTR polymorphism in the 3′-untranslated region of DAT1/SLC6A3 is associated with ADHD but not with alcoholism

Behavioral and Brain Functions, 2015
BackgroundADHD and alcoholism are psychiatric diseases with pathophysiology related to dopamine system. DAT1 belongs to the SLC6 family of transporters and is involved in the regulation of extracellular dopamine levels.
O. Šerý, I. Paclt, I. Drtílková, P. Theiner, M. Kopečková, P. Zvolský, V. Balcar   +6 more
semanticscholar   +1 more source

Development of a hierarchical variable-number tandem repeat typing scheme for Mycobacterium tuberculosis in China.

PLoS ONE, 2014
Molecular typing based on variable-number tandem repeats (VNTR) analysis is a promising tool for identifying transmission of Mycobacterium tuberculosis. However, the currently proposed 15- and 24-locus VNTR sets (VNTR-15/24) only have limited resolution ...
Tao Luo, Chongguang Yang, Yu Pang, Yanlin Zhao, Jian Mei, Qian Gao   +5 more
doaj   +1 more source

Molecular Typing of Mycobacterium Tuberculosis Complex by 24-Locus Based MIRU-VNTR Typing in Conjunction with Spoligotyping to Assess Genetic Diversity of Strains Circulating in Morocco

PLoS ONE, 2015
Background Standard 24-locus Mycobacterial Interspersed Repetitive Unit Variable Number Tandem Repeat (MIRU-VNTR) typing allows to get an improved resolution power for tracing TB transmission and predicting different strain (sub) lineages in a community.
Nada Bouklata, P. Supply, Sanae Jaouhari, R. Charof, F. Seghrouchni, K. Sadki, Y. El Achhab, C. Nejjari, A. Filali-Maltouf, Ouafae Lahlou, R. El Aouad   +10 more
semanticscholar   +1 more source

Mapping the omics landscape for peri‐implant diseases: A scoping review

Periodontology 2000, EarlyView.
Abstract Objectives To map omics evidence across peri‐implant health, peri‐implant mucositis, and peri‐implantitis, and to identify recurring molecular patterns and candidate biomarker signals relevant to diagnosis, monitoring, and treatment. Materials and Methods This scoping review included human studies using genomics, DNA methylation–based ...
Ethan Ng, Ioannis Fragkioudakis, Jeniffer Perussolo, John Rong Hao Tay, Elena Calciolari, Nikos Donos   +5 more
wiley   +1 more source

Genetic Diversity of Mycobacterium tuberculosis Isolates from Assam, India: Dominance of Beijing Family and Discovery of Two New Clades Related to CAS1_Delhi and EAI Family Based on Spoligotyping and MIRU-VNTR Typing

PLoS ONE, 2015
Tuberculosis (TB) is one of the major public health concerns in Assam, a remote state located in the northeastern (NE) region of India. The present study was undertaken to explore the circulating genotypes of Mycobacterium tuberculosis complex (MTBC) in ...
K. R. Devi, R. Bhutia, S. Bhowmick, K. Mukherjee, J. Mahanta, K. Narain   +5 more
semanticscholar   +1 more source

Clustering of Beijing genotype Mycobacterium tuberculosis isolates from the Mekong delta in Vietnam on the basis of variable number of tandem repeat versus restriction fragment length polymorphism typing

BMC Infectious Diseases, 2013
Background In comparison to restriction fragment length polymorphism (RFLP) typing, variable number of tandem repeat (VNTR) typing is easier to perform, faster and yields results in a simple, numerical format.
Huyen Mai NT, Kremer Kristin, Lan Nguyen TN, Buu Tran N, Cobelens Frank GJ, Tiemersma Edine W, de Haas Petra, van Soolingen Dick   +7 more
doaj   +1 more source

DPYD and UGT1A1 Genotype‐Based Dosing for Fluoropyrimidines and Irinotecan Chemotherapy: Variant‐Specific Impact on Treatment Intensity and Toxicity

International Journal of Cancer, Volume 159, Issue 10, Page 2512-2524, 15 November 2026.
Pre‐treatment DPYD and UGT1A1 genotyping is increasingly used to prevent fluoropyrimidine‐ and irinotecan‐related toxicity, but variant‐specific real‐world effects remain unclear. In an unselected cohort of cancer patients with actionable genotypes, genotype‐driven dosing improved safety while preserving treatment exposure in high‐risk DPYD c.1905+1G>A
Martina Gambron, Elena Peruzzi, Samantha Perfler, Marcella Montico, Riccardo Cecchin, Elena De Mattia, Michele Spina, Camilla Lisanti, Serena Corsetti, Luisa Foltran, Fabio Puglisi, Rossana Roncato, Erika Cecchin   +12 more
wiley   +1 more source