Results 61 to 70 of about 21,570 (220)

Impact of the Functional VNTR Variants of the Interleukin-1 Receptor Antagonist and Interleukin-4 Genes on Oral Squamous Cell Carcinoma

open access: yesİstanbul Medical Journal, 2019
Introduction:It has been shown that the host immune response and chronic inflammation could play a role as important risk factors for cancer. Oral squamous cell carcinoma (OSCC) is a common cancer worldwide. In this study, we aimed to evaluate the impact
Özge Gümüşay   +4 more
doaj   +1 more source

GENETIC DIVERSITY OF MYCOBACTERIUM AVIUM subsp. HOMINISSUIS STRAINS ISOLATED IN ITALY BASED ON VNTR LOCI ANALYSIS

open access: yesИнфекция и иммунитет, 2018
. Background. Mycobacterium avium subsp. hominissuis (MAH) is an important pathogen responsible for most of the human-associated nontuberculous mycobacteria infections.
M. Menichini   +3 more
doaj   +1 more source

Mutations causing medullary cystic kidney disease type 1 (MCKD1) lie in a large VNTR in MUC1 missed by massively parallel sequencing

open access: yesNature Genetics, 2013
Although genetic lesions responsible for some mendelian disorders can be rapidly discovered through massively parallel sequencing of whole genomes or exomes, not all diseases readily yield to such efforts.
Andrew W. Kirby   +42 more
semanticscholar   +1 more source

A Mycobacterium leprae VNTR database

open access: yesLeprosy Review, 2010
A great deal of the last quarter of a century’s astonishing progress in understanding and treating human disease is attributable to the existence of public databases where information about DNA sequences, protein sequences, protein structures, human variation, etc. is stored and is freely available to all interested investigators.
openaire   +2 more sources

Genome-wide prediction of human VNTRs

open access: yesGenomics, 2005
Polymorphic minisatellites, also known as variable number of tandem repeats (VNTRs), are tandem repeat regions that show variation in the number of repeat units among chromosomes in a population. Currently, there are no general methods for predicting which minisatellites have a high probability of being polymorphic, given their sequence characteristics.
Karl, Näslund   +5 more
openaire   +2 more sources

Development and analytical validation of a targeted short‐read next generation sequencing‐based pharmacogenetic panel for comprehensive variant detection

open access: yesBritish Journal of Pharmacology, Volume 183, Issue 16, Page 4735-4760, August 2026.
Abstract Background and Purpose Genomic profiling of patients for genetic variants that modify the effect of specific medications has many benefits, including the possibility of avoiding toxicities and ensuring an adequate effect of the medication. Our intention was to develop a comprehensive, high‐quality pharmacogenetic test panel for clinical use ...
Anna Gréen   +5 more
wiley   +1 more source

Meta-analysis of the DRD5 VNTR in persistent ADHD [PDF]

open access: yesEuropean Neuropsychopharmacology, 2016
Attention-Deficit/Hyperactivity Disorder (ADHD) is a common neuropsychiatric disorder with a complex genetic background. DRD5, the gene encoding the dopamine receptor D5, was recently confirmed as a candidate gene for ADHD in children through meta-analysis.
Klein, M.   +33 more
openaire   +3 more sources

Quantitative Control of Transposable Elements: From Genome Plasticity to Immune Regulatory Circuits

open access: yesCell Biochemistry and Function, Volume 44, Issue 7, July 2026.
ABSTRACT Transposable elements (TEs) constitute nearly half of the human genome and are increasingly recognized as context‐dependent regulators of genome function rather than passive repetitive DNA. This Review synthesizes classical and recent evidence on TE biology, including TE classification, mechanisms of mobilization, host restriction pathways ...
Irving Jesús Reyes‐Barragán
wiley   +1 more source

Spatio-Temporal Analysis of the Tularemia Agent Population in the Rostov Region, DPR, LPR and Ukraine from 1943 to 2023

open access: yesПроблемы особо опасных инфекций
The aim of the study was to conduct spatio-temporal retrospective and operational genetic analysis of the tularemia agent population in the Rostov Region, Donetsk People’s Republic (DPR), Lugansk PR and Ukraine in the period of 1943–2023.
V. M. Sorokin   +6 more
doaj   +1 more source

The Genoeconomics of Impulsive Intertemporal Choice: A Critical Review

open access: yesJournal of the Experimental Analysis of Behavior, Volume 126, Issue 1, July 2026.
Abstract Dr. Warren Bickel tirelessly investigated delay discounting (DD), a behavioral economic index of impulsive decision making, as a determinant of numerous health outcomes. Among the factors that contribute to a person's level of DD, a burgeoning body of research has illuminated its genetic foundations and the extent to which it may be a ...
Wei Q. Deng   +5 more
wiley   +1 more source

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