Results 81 to 90 of about 21,570 (220)

cuteHap: Haplotype‐Aware Structural Variant Detection in Phased Long‐Read Sequencing Data

Advanced Science, Volume 13, Issue 22, 17 April 2026.
cuteHap is a haplotype‐aware structural variant detection method designed for phased long‐read sequencing. By employing self‐adaptive clustering and credibility‐prioritized beam search algorithms, cuteHap generates accurate haplotype‐resolved calls and outperforms state‐of‐the‐art tools.
Shuqi Cao, Yadong Liu, Miao Cui, Runtian Gao, Weimin Guo, Guohua Wang, Yadong Wang, Tao Jiang   +7 more
wiley   +1 more source

Genotyping of genetically monomorphic bacteria: DNA sequencing in Mycobacterium tuberculosis highlights the limitations of current methodologies.

PLoS ONE, 2009
Because genetically monomorphic bacterial pathogens harbour little DNA sequence diversity, most current genotyping techniques used to study the epidemiology of these organisms are based on mobile or repetitive genetic elements. Molecular markers commonly
Iñaki Comas, Susanne Homolka, Stefan Niemann, Sebastien Gagneux   +3 more
doaj   +1 more source

Pan‐3D Genome Analysis Reveals the Roles of Structural Variation in Chicken Chromatin Architectures, Domestication and Production Traits

Advanced Science, Volume 13, Issue 24, 27 April 2026.
This study firstly presents a comprehensive and high‐resolution pan‐3D genome resource in chicken. Our findings reveal the role of structural variations in 3D genome architectures, and how they influence the domestication process and production traits at the 3D genome level.
Zhen Zhou, Danfeng Cai, Changbin Zhao, Siyu Zhang, Jiahao Li, Zhaofeng Zhang, Shaofen Kong, Xin Yang, Xiaoli Zhou, Farhad Bordbar, Fayi Chen, Yaohuan Xu, Zhe Zhang, Lihong Gu, Zhenhui Li, Xiquan Zhang, Wen Luo, Jingting Shu, Bolin Cai, Qinghua Nie   +19 more
wiley   +1 more source

Effect of seed circulation systems on the spread and diversity of Xanthomonas phaseoli pv. manihotis infecting cassava crops of the Colombian Caribbean

PLANTS, PEOPLE, PLANET, Volume 8, Issue 1, Page 353-364, January 2026.
Cassava is a lifeline for millions of people across the tropics, but its productivity is at risk from a disease called Cassava Bacterial Blight (CBB). In this study, we explore how the everyday practices of farmers exchanging cassava cuttings—a long‐standing tradition—can shape how the disease spreads and evolves in the Colombian Caribbean.
Darío Pérez, Laurence Blondin, Sophie Caillon, Olivier Pruvost, Boris Szurek, Christian Vernière, Carlos A. Zárate‐Chaves, Anne Duputié   +7 more
wiley   +1 more source

Molecular typing of Mycobacterium Abscessus isolated from cystic fibrosis patients

International Journal of Mycobacteriology, 2017
Background: The possibility of inter-human transmission of Mycobacterium abscessus in cystic fibrosis centres has been recently hypothesized suggesting the need for the molecular characterization of strains isolated from such patients.
Alberto Trovato, Rossella Baldan, Danila Costa, Tullia M Simonetti, Daniela M Cirillo, Enrico Tortoli   +5 more
doaj   +1 more source

Length of Variable Numbers of Tandem Repeats in the Carboxyl Ester Lipase (CEL) Gene May Confer Susceptibility to Alcoholic Liver Cirrhosis but Not Alcoholic Chronic Pancreatitis.

PLoS ONE, 2016
BackgroundCarboxyl-ester lipase (CEL) contributes to fatty acid ethyl ester metabolism, which is implicated in alcoholic pancreatitis. The CEL gene harbours a variable number of tandem repeats (VNTR) region in exon 11.
Karianne Fjeld, Sebastian Beer, Marianne Johnstone, Constantin Zimmer, Joachim Mössner, Claudia Ruffert, Mario Krehan, Christian Zapf, Pål Rasmus Njølstad, Stefan Johansson, Peter Bugert, Fabio Miyajima, Triantafillos Liloglou, Laura J Brown, Simon A Winn, Kelly Davies, Diane Latawiec, Bridget K Gunson, David N Criddle, Munir Pirmohamed, Robert Grützmann, Patrick Michl, William Greenhalf, Anders Molven, Robert Sutton, Jonas Rosendahl   +25 more
doaj   +1 more source

Long‐read sequencing reveals SVA insertion in AP3B1 causing Hermansky–Pudlak syndrome 2

Pediatric Allergy and Immunology, Volume 37, Issue 7, July 2026.
Naomi Baba, Ahmed Elashy, Oliver Wegehaupt, Barbara Zieger, Melisa Felek, Micol Ferro, Kimberly Gilmour, Ute Fischer, Arndt Borkhardt, Stephan Ehl, David Koppstein, Sujal Ghosh   +11 more
wiley   +1 more source

Increased Risk of Gastric Cancer with VNTR Polymorphism of SIRT3 Gene

Journal of Mazandaran University of Medical Sciences, 2017
Background and purpose: Gastric cancer is the most common cancer associated with high mortality worldwide. One of the genes that is down-regulated in gastric cancer, is the SIRT3 that encodes the histone deacetylase enzyme.
Saghar Mohammadi, Parisa Mohamadynejad, Mehdi Moghanibashi   +2 more
doaj  

Genomic Survey of Pathogenicity Determinants and VNTR Markers in the Cassava Bacterial Pathogen Xanthomonas axonopodis pv. Manihotis Strain CIO151

PLoS ONE, 2013
Xanthomonas axonopodis pv. manihotis (Xam) is the causal agent of bacterial blight of cassava, which is among the main components of human diet in Africa and South America.
Mario L. Arrieta-Ortiz, L. Rodriguez-R., Alvaro L Perez Quintero, L. Poulin, A. C. Díaz, Nathalia Arias Rojas, César A. Trujillo, Mariana Restrepo Benavides, R. Bart, J. Boch, Tristan Boureau, A. Darrasse, Perrine David, Thomas Dugé de Bernonville, P. Fontanilla, L. Gagnevin, F. Guérin, M. Jacques, E. Lauber, P. Lefeuvre, C. Medina, E. Medina, N. Montenegro, Alejandra Muñoz Bodnar, L. Noël, Juan F. Ortiz Quiñones, D. Osorio, C. Pardo, P. Patil, S. Poussier, O. Pruvost, I. Robène-Soustrade, R. Ryan, J. Tabima, Oscar Urrego Morales, C. Vernière, S. Carrère, V. Verdier, B. Szurek, S. Restrepo, Camilo A. López, R. Koebnik, A. Bernal   +42 more
semanticscholar   +1 more source

A quantitative and efficient approach to select MIRU–VNTR loci based on accumulation of the percentage differences of strains for discriminating divergent Mycobacterium tuberculosis sublineages

Emerging Microbes and Infections, 2017
Although several optimal mycobacterial interspersed repetitive units–variable number tandem repeat (MIRU–VNTR) loci have been suggested for genotyping homogenous Mycobacterium tuberculosis, including the Beijing genotype, a more efficient and convenient ...
Xin-Ling Pan, Chun-Lei Zhang, Chie Nakajima, Jin Fu, Chang-Xia Shao, Li-Na Zhao, Jia-Yi Cui, Na Jiao, Chang-Long Fan, Yasuhiko Suzuki, Toshio Hattori, Di Li, Hong Ling   +12 more
doaj   +1 more source