Results 11 to 20 of about 19,754 (301)
Are volatile anesthetics neuroprotective or neurotoxic? [PDF]
Medical Gas Research, 2012 Volatile anesthetics are one class of the most commonly used drugs. However, the mechanisms for these drugs to induce anesthesia are not fully understood and have been under intensive investigation.
Zuo, Zhiyi
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Development of a simple method for differential delivery of volatile anesthetics to the spinal cord of the rabbit. [PDF]
PLoS ONE, 2020 Emulsified volatile anesthetic can be directly injected into the circulation and eliminated from blood through lungs. Taking advantage of the unique pharmacokinetics of the emulsified volatile anesthetics, we aimed to develop a less traumatic method to ...
Peng Zhang, Yao Li, Ting Xu
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Age-dependent cerebral vasodilation induced by volatile anesthetics is mediated by NG2+ vascular mural cells [PDF]
Communications BiologyAnesthesia can influence cerebral blood flow by altering vessel diameter. Using in vivo two-photon imaging, we examined the effects of volatile anesthetics, sevoflurane and isoflurane, on vessel diameter in young and adult mice.
Hang Zhou +4 more
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Volatile anesthetics as a neuroprotective agent [PDF]
Korean Journal of Anesthesiology, 2011 Pharmacologic protection of brain from ischemic insult has been intensively investigated since the early 1960s [1] and a considerable amount of work has been performed to show the effectiveness of various drugs. Among these studies, anesthetic agents, including intravenous and volatile drugs, were shown to be promising agents.
Sungsik Park
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Volatile anesthetics and ischemia-reperfusion injury [PDF]
Korean Journal of Anesthesiology, 2015 Ischemia-reperfusion (IR) injury can occur under various clinical conditions in which the restoration of blood and oxygen to ischemic tissues results in a massive release of oxygen free radicals. For example, cardiac surgery, stroke, tourniquet application for orthopedic surgery, organ transplantation, and restoration of shock can cause IR injury ...
Hong-Beom Bae
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PLoS ONE, 2020 We evaluated whether volatile anesthetics can improve the postoperative outcomes of non-cardiac surgery in patients with preoperative myocardial injury defined by the cardiac troponin elevation.
Jungchan Park +7 more
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Volatile Anesthetics and Immunity. [PDF]
Immunol Invest, 2017 Historically, volatile anesthetics have demonstrated interesting interactions with both the innate and adaptive immune systems. This review organizes these interactions into four phases: recognition, recruitment, response, and resolution. These phases represent a range of proinflammatory, inflammatory, and innate and adaptive immune regulatory ...
Sedghi S +3 more
europepmc +5 more sources
Age and Solubility of Volatile Anesthetics in Blood [PDF]
Anesthesiology, 1984 The more rapid rate of rise of alveolar anesthetic partial pressure in children compared with adults may be explained in part by an increasing solubility of volatile anesthetics in blood with age. To investigate this possibility, the authors measured the blood-gas partition coefficients of isoflurane, enflurane, halothane, and methoxyflurane in four ...
Jerrold Lerman +2 more
openalex +5 more sources
The Differential Effects of Anesthetics on Bacterial Behaviors. [PDF]
PLoS ONE, 2017 Volatile anesthetics have been in clinical use for a long period of time and are considered to be promiscuous by presumably interacting with several ion channels in the central nervous system to produce anesthesia. Because ion channels and their existing
Matthew Chamberlain +5 more
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Volatile anesthetics influence blood-brain barrier integrity by modulation of tight junction protein expression in traumatic brain injury. [PDF]
PLoS ONE, 2012 Disruption of the blood-brain barrier (BBB) results in cerebral edema formation, which is a major cause for high mortality after traumatic brain injury (TBI).
Serge C Thal +7 more
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