Results 41 to 50 of about 694,198 (334)
Hydrocarbon molar water solubility predicts NMDA vs. GABAA receptor modulation. [PDF]
, 2014 BackgroundMany anesthetics modulate 3-transmembrane (such as NMDA) and 4-transmembrane (such as GABAA) receptors. Clinical and experimental anesthetics exhibiting receptor family specificity often have low water solubility. We hypothesized that the molar
Brosnan, Robert J, Pham, Trung L
core +2 more sources
Volatile Anesthetics versus Total Intravenous Anesthesia for Cardiac Surgery
New England Journal of Medicine, 2019 BACKGROUND Volatile (inhaled) anesthetic agents have cardioprotective effects, which might improve clinical outcomes in patients undergoing coronary‐artery bypass grafting (CABG).
G. Landoni +45 more
semanticscholar +1 more source
Effects of Anesthetics on Barrier Tissue Function
Journal of Immunology Research, 2019 Anesthetics have long been proven to have additional effects other than anesthesia on different organs and tissues of the human body. Barrier tissues play critical roles in human health and diseases, yet the impacts of anesthetics on barrier tissues are ...
Fujing Wang +4 more
doaj +1 more source
SLO-2 is cytoprotective and contributes to mitochondrial potassium transport. [PDF]
PLoS ONE, 2011 Mitochondrial potassium channels are important mediators of cell protection against stress. The mitochondrial large-conductance "big" K(+) channel (mBK) mediates the evolutionarily-conserved process of anesthetic preconditioning (APC), wherein exposure ...
Andrew P Wojtovich +5 more
doaj +1 more source
Desflurane Selectively Suppresses Long-latency Cortical Neuronal Response to Flash in the Rat [PDF]
, 2009 Background—The effect of inhalational anesthetics on sensory-evoked unit activity in the cerebral cortex has been controversial. Desflurane has desirable properties for in vivo neurophysiologic studies but its effect on cortical neuronal activity and ...
Hudetz, Anthony G. +2 more
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Monosynaptic Functional Connectivity in Cerebral Cortex During Wakefulness and Under Graded Levels of Anesthesia [PDF]
, 2012 The balance between excitation and inhibition is considered to be of significant importance for neural computation and cognitive function. Excitatory and inhibitory functional connectivity in intact cortical neuronal networks in wakefulness and graded ...
Diba, Kamran +4 more
core +3 more sources
A Double-Edged Sword: Volatile Anesthetic Effects on the Neonatal Brain
Brain Sciences, 2014 The use of volatile anesthetics, a group of general anesthetics, is an exceedingly common practice. These anesthetics may have neuroprotective effects. Over the last decade, anesthetic induced neurotoxicity in pediatric populations has gained a certain ...
Sunny Chiao, Zhiyi Zuo
doaj +1 more source
PLoS ONE, 2021 PurposePatients undergo dilatation and evacuation for abortion or miscarriage. However, bleeding is sometimes problematic. Despite reports on the association between volatile anesthetics and increased bleeding during the procedure, firm evidence is ...
Hyun Ah Lee +4 more
doaj +1 more source
Total intravenous anesthesia for liver resections: anesthetic implications and safety [PDF]
Korean Journal of Anesthesiology, 2022 Inhalational anesthetics have been the default agents for general anesthesia maintenance for several decades. However, with advances in total intravenous anesthesia (TIVA) and a growing body of evidence on the potential benefits of TIVA ...
Selene Yan Ling Tan, Nian Chih Hwang
doaj +1 more source
The FASEB Journal, 2019 General anesthesia has been the requisite component of surgical procedures for over 150 yr. Although immunomodulatory effects of volatile anesthetics have been growingly appreciated, the molecular mechanism has not been understood.
T. Okuno +7 more
semanticscholar +1 more source