Results 41 to 50 of about 19,426 (298)

General Anesthetics in Cancer Surgery: Can Anesthesiologists Help the Patient with More than a Safe Sleep

Medicina, 2022
Most patients suffering from neoplastic diseases will at some point during their illness be approached surgically. Surgery itself may be unfortunately responsible for tumor proliferation and metastatic spread.
John Michael Bonvini
doaj   +1 more source

SNARE proteins as molecular masters of interneuronal communication [PDF]

, 2010
In the beginning of the 20th century the groundbreaking work\ud of Ramon y Cajal firmly established the neuron doctrine, according to which neurons are the basic structural and functional units of the nervous system. Von Weldeyer coined the term “neuron”
Georgiev, Danko D., Glazebrook, James F.
core   +2 more sources

Sedating Mechanically Ventilated COVID-19 Patients with Volatile Anesthetics: Insights on the Last-Minute Potential Weapons

Scientia Pharmaceutica, 2021
Coronavirus Disease 2019 (COVID-19) has spread globally with the number of cases exceeding seventy million. Although trials on potential treatments of COVID-19 Acute Respiratory Distress Syndrome (ARDS) are promising, the introduction of an effective ...
Aiman Suleiman, Abdallah Barjas Qaswal, Mazen Alnouti, Moh’d Yousef, Bayan Suleiman, Mohammad El Jarbeh, Ghadeer Alshawabkeh, Isam Bsisu, Abeer Santarisi, Muaweih Ababneh   +9 more
doaj   +1 more source

Volatile anesthetics alter protein stability

Toxicology Letters, 1998
1. We have used differential scanning calorimetry to measure the halothane induced change in stability of five lipid-free proteins in aqueous solution. 2. The temperature at peak heat capacity (Tm) as the sample is heated provides a measure of stability. 3.
J W, Tanner, P A, Liebman, R G, Eckenhoff   +2 more
openaire   +2 more sources

Inhibition of firefly luciferase by general anesthetics: effect on in vitro and in vivo bioluminescence imaging. [PDF]

PLoS ONE, 2012
UNLABELLED: Bioluminescence imaging is routinely performed in anesthetized mice. Often isoflurane anesthesia is used because of its ease of use and fast induction/recovery.
Marleen Keyaerts, Isabel Remory, Vicky Caveliers, Karine Breckpot, Tomas J Bos, Jan Poelaert, Axel Bossuyt, Tony Lahoutte   +7 more
doaj   +1 more source

USE OF INHALANT ANESTHETICS IN THREE SNAKE SPECIES [PDF]

, 2000
Different snake species respond differently to various anesthetic agents. Hence, an anesthetic procedure developed for one species cannot necessarily be safely transferred to another species.
Blouin-Demers, Gabriel, Brown, Gregory P., Parent, Christopher E., Shilton, Catherine M., Weatherhead, Patrick J.   +4 more
core   +2 more sources

Sevoflurane Pre-conditioning Ameliorates Diabetic Myocardial Ischemia/Reperfusion Injury Via Differential Regulation of p38 and ERK. [PDF]

, 2020
Diabetes mellitus (DM) significantly increases myocardial ischemia/reperfusion (MI/R) injury. During DM, cardioprotection induced by conventional pre-conditioning (PreCon) is decreased due to impaired AMP-activated protein kinase (AMPK) signaling.
Cao, Jimin, Christopher, Theodore, Gao, Erhe, Guo, Rui, Jiao, Liyuan, Lau, Wayne Bond, Lopez, Bernard, Ma, Xin-Liang, Wang, Yajing, Xie, Dina, Zhang, Yanqing, Zhao, Jianli   +11 more
core   +1 more source

Perioperative Neurocognitive Disorder: State of the Preclinical Science. [PDF]

, 2020
The purpose of this article is to provide a succinct summary of the different experimental approaches that have been used in preclinical postoperative cognitive dysfunction research, and an overview of the knowledge that has accrued. This is not intended
Culley, Deborah J, Eckenhoff, Maryellen F, Eckenhoff, Roderic G, Goodlin, Sarah J, Maze, Mervyn, Orser, Beverley A, Terrando, Niccolò, Wei, Huafeng, Whittington, Robert A, Xie, Zhongcong, Zuo, Zhiyi   +10 more
core  

High-throughput screening in larval zebrafish identifies novel potent sedative-hypnotics [PDF]

, 2018
BACKGROUND: Many general anesthetics were discovered empirically, but primary screens to find new sedative-hypnotics in drug libraries have not used animals, limiting the types of drugs discovered.
Brown, Lauren E., Dai, Jennifer B., Daigle, Renee, Forman, Stuart A., Halpin, Elizabeth S., Jounaidi, Youssef, Marte-Oquendo, Francisco, Porco, John A., Schaus, Scott E., Trilles, Richard, Xu, Wenqing, Yang, Xiaoxuan, Yu, Buwei   +12 more
core   +1 more source

Enhanced Infection Resistance and Regenerative Healing of Titanium Implants via Peptide‐Loaded Biodegradable Coatings

Advanced Materials Technologies, EarlyView.
This study presents a new biodegradable coating for titanium implants using a natural antimicrobial peptide, caerin 1.9. Applied via solvent casting, the coating offers sustained antibacterial protection and promotes healing. Tested on 3D‐printed porous titanium scaffolds, it effectively prevented infection—including against resistant bacteria—while ...
Hejie Li, Tianfang Wang, Nicolas Soro, Guoying Ni, Meg Allom, D. İpek Kurtböke, Xiaosong Liu, Damon Kent   +7 more
wiley   +1 more source