Results 81 to 90 of about 91,818 (287)

MAP3Kinase-dependent SnRK2-kinase activation is required for abscisic acid signal transduction and rapid osmotic stress response. [PDF]

, 2020
Abiotic stresses, including drought and salinity, trigger a complex osmotic-stress and abscisic acid (ABA) signal transduction network. The core ABA signalling components are snf1-related protein kinase2s (SnRK2s), which are activated by ABA-triggered ...
Ceciliato, Paulo HO, Dubeaux, Guillaume, Ge, Chennan, Hauser, Felix, Hsu, Po-Kai, Munemasa, Shintaro, Schroeder, Julian I, Takahashi, Yohei, Zhang, Jingbo, Zhang, Li, Zhao, Yunde   +10 more
core  

Theory of membrane capacitive deionization including the effect of the electrode pore space [PDF]

, 2011
Membrane capacitive deionization (MCDI) is a technology for water desalination based on applying an electrical field between two oppositely placed porous electrodes.
Biesheuvel, P.M., Porada, S., Wal, A., van der, Zhao, R.   +3 more
core   +2 more sources

The BH4 Domain of Anti-apoptotic Bcl-XL, but Not That of the Related Bcl-2, Limits the Voltage-dependent Anion Channel 1 (VDAC1)-mediated Transfer of Pro-apoptotic Ca2+ Signals to Mitochondria*

Journal of Biological Chemistry, 2015
Background: VDAC1 mediates the transfer of pro-apoptotic Ca2+ signals into mitochondria. Results: The BH4 domain of Bcl-XL, but not that of Bcl-2, targets VDAC1 and suppresses its pro-apoptotic Ca2+-flux properties.
G. Monaco, E. Decrock, Nir Arbel, A. V. van Vliet, R. L. La Rovere, H. de Smedt, J. Parys, P. Agostinis, L. Leybaert, V. Shoshan-Barmatz, G. Bultynck   +10 more
semanticscholar   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

The pathogen Moniliophthora perniciosa promotes differential proteomic modulation of cacao genotypes with contrasting resistance to witches´ broom disease [PDF]

, 2020
Background: Witches' broom disease (WBD) of cacao (Theobroma cacao L.), caused by Moniliophthora perniciosa, is the most important limiting factor for the cacao production in Brazil.
Correa, Stephany Cristiane, Cruz dos Santos, Everton, Gramacho, Karina Peres, Micheli, Fabienne, Pirovani, Carlos Priminho   +4 more
core   +1 more source

Peripheral benzodiazepine receptor regulates vascular endothelial activations via suppression of the voltage‐dependent anion channel‐1 [PDF]

FEBS Letters, 2012
Peripheral benzodiazepine receptor (PBR) is a multifunctional protein mainly found on the outer mitochondrial membrane. PBR expression is increased by tumor necrosis factor‐α (TNF‐α) in endothelial cells. Adenoviral overexpression of PBR inhibits monocyte adhesion, VCAM‐1, and ICAM‐1 expression in TNF‐α‐activated endothelial cells.
Joo, Hee Kyoung, Lee, Yu Ran, Lim, Sun Young, Lee, Eun Ji, Choi, Sunga, Cho, Eun Jung, Park, Myoung Soo, Ryoo, Sungwoo, Park, Jin Bong, Jeon, Byeong Hwa   +9 more
openaire   +2 more sources

Chameleon sequences reveal structural effects in proteins representing micelle‐like distribution of hydrophobicity

FEBS Open Bio, EarlyView.
Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman, Katarzyna Stapor, Leszek Konieczny, Krzysztof Gądek, Piotr Nowakowski   +4 more
wiley   +1 more source

Single-channel recordings from cultured human retinal pigment epithelial cells. [PDF]

, 1988
We have applied patch-clamp techniques to on-cell and excised-membrane patches from human retinal pigment epithelial cells in tissue culture. Single-channel currents from at least four ion channel types were observed: three or more potassium-selective ...
Fain, GL, Fox, JA, Pfeffer, BA
core  

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Ryanodine receptors are targeted by anti-apoptotic Bcl-X-L involving its BH4 domain and Lys87 from its BH3 domain [PDF]

, 2015
Anti-apoptotic B-cell lymphoma 2 (Bcl-2) family members target several intracellular Ca2+-transport systems. Bcl-2, via its N-terminal Bcl-2 homology (BH) 4 domain, inhibits both inositol 1,4,5-trisphosphate receptors (IP(3)Rs) and ryanodine receptors ...
Bultynck, Geert, De Smedt, Humbert, Decrock, Elke, Ivanova, Hristina, Kasri, Nael Nadif, Lemmens, Irma, Leybaert, Luc, Martens, Lennart, Missiaen, Ludwig, Monaco, Giovanni, Parys, Jan B, Sorrentino, Vincenzo, Tavernier, Jan, Vandermarliere, Elien, Vervliet, Tim   +14 more
core   +1 more source