Results 71 to 80 of about 91,818 (287)
Voltage‐dependent anion channel (
Genes to Cells, 2015 The Ras–MAP kinase signaling pathway plays important roles for the olfactory reception in olfactory neurons in Caenorhabditis elegans. However, given the absence of phosphorylation targets of MAPK in the olfactory neurons, the mechanism by which this pathway regulates olfactory function is unknown.
Takayuki, Uozumi +4 more
openaire +2 more sources
A novel regulator of selective autophagy: TNIP1/ABIN-1 modulates mitophagy
Autophagy Reports, 2023 TNIP1/ABIN-1 is a novel inhibitor of inflammation and cell death. In our study, we elucidated the MAP1LC3/LC3 (microtubule associated protein 1 light chain 3)-interacting region (LIR) 1 and 2 motifs of TNIP1-dependent direct binding to LC3B-II and ...
Rosetta Merline, Liliana Schaefer
doaj +1 more source
secCl is a cys-loop ion channel necessary for the chloride conductance that mediates hormone-induced fluid secretion in Drosophila [PDF]
, 2019 Organisms use circulating diuretic hormones to control water balance (osmolarity), thereby avoiding dehydration and managing excretion of waste products.
Dent, J. +6 more
core +2 more sources
Human erythroid differentiation requires VDAC1-mediated mitochondrial clearance
Haematologica, 2021 Erythroblast maturation in mammals is dependent on organelle clearance throughout terminal erythropoiesis. We studied the role of the outer mitochondrial membrane protein voltage-dependent anion channel-1 (VDAC1) in human terminal erythropoiesis.
Martina Moras +10 more
doaj +1 more source
Identification of Bax–voltage‐dependent anion channel 1 complexes in digitonin‐solubilized cerebellar granule neurons [PDF]
Journal of Neurochemistry, 2011 J. Neurochem. (2011) 119, 1137–1150.AbstractMitochondrial outer membrane Bax oligomers are critical for cytochrome c release, but the role of resident mitochondrial proteins in this process remains unclear. Membrane‐associated Bax has primarily been studied using 3‐[(3‐cholamidopropyl)dimethylammonio]‐1‐propanesulfonate (CHAPS) as the solubilizing ...
Dennis B, Huckabee, Mika B, Jekabsons
openaire +2 more sources
Journal of Enzyme Inhibition and Medicinal Chemistry, 2023 The mitochondrial voltage-dependent anion channel 1 (VDAC1) plays a central role in metabolism and apoptosis, which makes it a promising therapeutic target. Nevertheless, molecular mechanisms governing VDAC1 functioning remain unclear.
Hubert Gorny +5 more
doaj +1 more source
Osmotic Edema Rapidly Increases Neuronal Excitability Through Activation of NMDA Receptor-Dependent Slow Inward Currents in Juvenile and Adult Hippocampus. [PDF]
, 2015 Cellular edema (cell swelling) is a principal component of numerous brain disorders including ischemia, cortical spreading depression, hyponatremia, and epilepsy.
Binder, Devin K +5 more
core +3 more sources
Effects of aminoperimidine on electrolyte transport across amphibian skin [PDF]
, 1998 The effect of aminoperimidine (AP)on transepithelial Na+ transport and Cl- conductance (G(Cl)) of isolated amphibian skin (Bufo viridis and Rana esculenta) was analyzed using transepithelial and intracellular electrophysiological techniques.
Katz, U., Nagel, W., Shalitin, Y.
core +1 more source
PLoS Pathogens, 2023 Pneumonia is a worldwide threat, making discovery of novel means to combat lower respiratory tract infection an urgent need. Manipulating the lungs' intrinsic host defenses by therapeutic delivery of certain pathogen-associated molecular patterns ...
Yongxing Wang +14 more
doaj +1 more source
Neoplasia: An International Journal for Oncology Research, 2023 Voltage-dependent anion-selective channel protein 1 (VDAC1) is the most abundant protein in the mitochondrial outer membrane and plays a crucial role in the control of hepatocellular carcinoma (HCC) progress.
Jinxin Zhang +17 more
doaj +1 more source