Results 191 to 200 of about 13,998 (216)
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[Voltage-dependent anion channels (VDAC) on human sperm membrane].

Zhonghua nan ke xue = National journal of andrology, 2007
To further study gene expression and characterization of voltage-dependent anion channels (VDACs) on human spermatozoa.VDACs were cloned by PCR from the testis cDNA library. Recombinant human sperm VDACs were produced in E. coli system by molecular cloning technology.
Zeng-jun, Wang   +3 more
openaire   +1 more source

Mitochondrial voltage-dependent anion channels (VDACs) as novel pharmacological targets for anti-cancer agents

Journal of Bioenergetics and Biomembranes, 2008
Recently, it was demonstrated that some anti-cancer agents used mitochondrial voltage-dependent anion channels (VDAC1-3 isoforms) as their pharmacological target. VDACs are expressed more highly in cancer cells than normal cells; thus the VDAC-dependent cytotoxic agents can have cancer-selectivity. Furanonaphthoquinones (FNQs) induced caspase-dependent
Eriko, Simamura   +3 more
openaire   +2 more sources

The Voltage-Dependent Anion Channel (VDAC): Function in Intracellular Signalling, Cell Life and Cell Death

Current Pharmaceutical Design, 2006
Research over the last decade has extended the prevailing view of mitochondria to include functions well beyond the critical bioenergetics role in supplying ATP. It is now recognized that mitochondria play a crucial role in cell signaling events, inter-organelle communication, aging, many diseases, cell proliferation and cell death.
V, Shoshan-Barmatz   +3 more
openaire   +2 more sources

Multiple cDNAs of wheat voltage-dependent anion channels (VDAC): Isolation, differential expression, mapping and evolution

Plant Molecular Biology, 1995
The mitochondrial outer membrane of eukaryotic cells contains voltage-dependent anion channels (VDAC) also termed porins. Three cDNAs from wheat (Triticum aestivum) were isolated and sequenced (Tavdac 1-3). They share 65% similarity of their amino acid sequences, and therefore they probably represent isoforms.
Elkeles, A.   +4 more
openaire   +3 more sources

Intracellular localization and isoform expression of the voltage-dependent anion channel (VDAC) in normal and dystrophic skeletal muscle.

Journal of muscle research and cell motility, 2000
Voltage-dependent anion channels (VDACs) are a family of pore-forming proteins encoded by different genes, with at least three protein products expressed in mammalian tissues. The major recognized functional role of VDACs is to permit the almost free permeability of the outer mitochondrial membrane (OMM).
MASSA, ROBERTO   +7 more
openaire   +5 more sources

New functions of an old protein: the eukaryotic porin or voltage dependent anion selective channel (VDAC).

The Italian journal of biochemistry, 2003
Mitochondrial porin or VDAC (Voltage Dependent Anion selective Channels) was identified for the first time in 1976, on the basis of the evolutionary similarity between the gram negative and mitochondrial outer membranes. Since this achievement VDAC has been extensively investigated: its functional features have been sharply defined upon reconstitution ...
Vito, De Pinto   +13 more
openaire   +2 more sources

Establishing the role of the mitochondrial voltage-dependent anion channel (VDAC) in Trypanosoma cruzi

Biophysical Journal, 2023
Sebastian Mesones Mancilla   +2 more
openaire   +1 more source

The Voltage-Dependant Anion Channel (VDAC) is SGlutathionylated in Ins2Akita Derived Β-Cells

Free Radical Biology and Medicine, 2013
Michelle S. Johnson   +8 more
openaire   +1 more source

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